CD5 Monoclonal Antibody (53-7.3), APC, eBioscience™ | Invitrogen 17-0051-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD5 Monoclonal Antibody (53-7.3), APC, eBioscience™

catalog :

17-0051-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

53-7.3

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 1d	Kreuk L, Koch M, Slayden L, Lind N, Chu S, Savage H, et al. B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota. elife. 2019;8: pubmed publisher
	Gal Oz S, Maier B, Yoshida H, Seddu K, Elbaz N, Czysz C, et al. ImmGen report: sexual dimorphism in the immune system transcriptome. Nat Commun. 2019;10:4295 pubmed publisher
	Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
	Niemeyer B, Oko L, Medina E, Oldenburg D, White D, Cool C, et al. Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis. J Virol. 2018;92: pubmed publisher
	Märklin M, Heitmann J, Fuchs A, Truckenmüller F, Gutknecht M, Bugl S, et al. NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia. Nat Commun. 2017;8:755 pubmed publisher
	Ren G, Jin W, Cui K, Rodrigez J, Hu G, Zhang Z, et al. CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression. Mol Cell. 2017;67:1049-1058.e6 pubmed publisher
	Schwartz C, Khan A, Floudas A, Saunders S, Hams E, Rodewald H, et al. ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control. J Exp Med. 2017;214:2507-2521 pubmed publisher
	Freitas C, Hamblin G, Raymond C, Weber K. Naïve helper T cells with high CD5 expression have increased calcium signaling. PLoS ONE. 2017;12:e0178799 pubmed publisher
	Fenouille N, Bassil C, Ben Sahra I, Benajiba L, Alexe G, Ramos A, et al. The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. Nat Med. 2017;23:301-313 pubmed publisher
	Alrefai H, Muhammad K, Rudolf R, Pham D, Klein Hessling S, Patra A, et al. NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. Nat Commun. 2016;7:11724 pubmed publisher
	Srikakulapu P, Hu D, Yin C, Mohanta S, Bontha S, Peng L, et al. Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice. Arterioscler Thromb Vasc Biol. 2016;36:1174-85 pubmed publisher
	Fiala G, Janowska I, Prutek F, Hobeika E, Satapathy A, Sprenger A, et al. Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation. J Exp Med. 2015;212:1693-708 pubmed publisher
	Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed publisher
	Reynolds A, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. J Immunol. 2015;194:231-42 pubmed publisher
	Singer K, Delproposto J, Morris D, Zamarron B, Mergian T, Maley N, et al. Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells. Mol Metab. 2014;3:664-75 pubmed publisher
	Honjo K, Kubagawa Y, Suzuki Y, Takagi M, Ohno H, Bucy R, et al. Enhanced auto-antibody production and Mott cell formation in Fc?R-deficient autoimmune mice. Int Immunol. 2014;26:659-72 pubmed publisher
	Kasler H, Lim H, Mottet D, Collins A, Lee I, Verdin E. Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance. EMBO J. 2012;31:4453-65 pubmed publisher
	Szczepanek S, McNamara J, Secor E, Natarajan P, Guernsey L, Miller L, et al. Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease. Am J Pathol. 2012;181:1725-34 pubmed publisher
	Rutemark C, Alicot E, Bergman A, Ma M, Getahun A, Ellmerich S, et al. Requirement for complement in antibody responses is not explained by the classic pathway activator IgM. Proc Natl Acad Sci U S A. 2011;108:E934-42 pubmed publisher
	Gibb D, El Shikh M, Kang D, Rowe W, El Sayed R, Cichy J, et al. ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. J Exp Med. 2010;207:623-35 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD5 Monoclonal Antibody (53-7.3), APC, eBioscience™

Catalog # :

17-0051-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

53-7.3

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly-12; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product

more info or order :

Invitrogen product webpage