product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IFN beta Monoclonal Antibody (A1 (IFNb)), Functional Grade, eBioscience
catalog :
16-9978-81
quantity :
50 µg
price :
US 225
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A1 (IFNb)
reactivity :
human
application :
neutralization, blocking or activating experiments
more info or order :
Invitrogen product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; loading ...; fig 5a
Decalf J, Desdouits M, Rodrigues V, Gobert F, Gentili M, Marques Ladeira S, et al. Sensing of HIV-1 Entry Triggers a Type I Interferon Response in Human Primary Macrophages. J Virol. 2017;91: pubmed publisher
Coelho L, Magno de Freitas Almeida G, Mennechet F, Blangy A, Uze G. Interferon-alpha and -beta differentially regulate osteoclastogenesis: role of differential induction of chemokine CXCL11 expression. Proc Natl Acad Sci U S A. 2005;102:11917-22 pubmed
product information
Product Type :
Antibody
Product Name :
IFN beta Monoclonal Antibody (A1 (IFNb)), Functional Grade, eBioscience
Catalog # :
16-9978-81
Quantity :
50 µg
Price :
US 225
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
Species :
Human
Clone :
A1 (IFNb)
Isotype :
IgG1, kappa
Storage :
4° C
Description :
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Format :
Liquid
Applications w/Dilutions :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
Fibroblast interferon; Ifb; IFF; IFN b; IFN ß; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNß; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA