LAP (Latency Associated peptide) Monoclonal Antibody (VB3A9), Functional Grade, eBioscience | Invitrogen 16-9823-82 product information

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product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LAP (Latency Associated peptide) Monoclonal Antibody (VB3A9), Functional Grade, eBioscience

catalog :

16-9823-82

quantity :

100 ug

price :

US 228.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

VB3A9

reactivity :

human

application :

western blot, immunoprecipitation

citations: 1

Reference
Annes J, Chen Y, Munger J, Rifkin D. Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1. J Cell Biol. 2004;165:723-34 pubmed

product information

Product Type :

Antibody

Product Name :

LAP (Latency Associated peptide) Monoclonal Antibody (VB3A9), Functional Grade, eBioscience

Catalog # :

16-9823-82

Quantity :

100 ug

Price :

US 228.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunoprecipitation: Assay-Dependent, Western Blot: 5 ug/mL

Species :

Human

Clone :

VB3A9

Isotype :

IgG1

Storage :

4 C

Description :

TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay-Dependent, Western Blot: 5 ug/mL

Aliases :

CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1