KLRG1 Monoclonal Antibody (13F12F2), Functional Grade, eBioscience | Invitrogen 16-9488-85 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KLRG1 Monoclonal Antibody (13F12F2), Functional Grade, eBioscience

catalog :

16-9488-85

quantity :

500 µg

price :

US 448.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13F12F2

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:33; loading ...; fig 6d	Karimzadeh H, Kiraithe M, Oberhardt V, Salimi Alizei E, Bockmann J, Schulze zur Wiesch J, et al. Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level. Gastroenterology. 2019;156:1820-1833 pubmed publisher
	Rouers A, Chng M, Lee B, Rajapakse M, Kaur K, Toh Y, et al. Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection. Cell Rep Med. 2021;2:100278 pubmed publisher
	Corgnac S, Lecluse Y, Mami Chouaib F. Isolation of tumor-resident CD8+ T cells from human lung tumors. STAR Protoc. 2021;2:100267 pubmed publisher
	Rha M, Jeong H, Ko J, Choi S, Seo I, Lee J, et al. PD-1-Expressing SARS-CoV-2-Specific CD8+ T Cells Are Not Exhausted, but Functional in Patients with COVID-19. Immunity. 2021;54:44-52.e3 pubmed publisher
	Golebski K, Ros X, Nagasawa M, van Tol S, Heesters B, Aglmous H, et al. IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation. Nat Commun. 2019;10:2162 pubmed publisher
	Rosental B, Kowarsky M, Seita J, Corey D, Ishizuka K, Palmeri K, et al. Complex mammalian-like haematopoietic system found in a colonial chordate. Nature. 2018;564:425-429 pubmed publisher
	Chockley P, Chen J, Chen G, Beer D, Standiford T, Keshamouni V. Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer. J Clin Invest. 2018;128:1384-1396 pubmed publisher
	Shi L, Wang J, Ren J, Cheng Y, Ying R, Wu X, et al. KLRG1 impairs CD4+ T cell responses via p16ink4a and p27kip1 pathways: role in hepatitis B vaccine failure in individuals with hepatitis C virus infection. J Immunol. 2014;192:649-57 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KLRG1 Monoclonal Antibody (13F12F2), Functional Grade, eBioscience

Catalog # :

16-9488-85

Quantity :

500 µg

Price :

US 448.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Species :

Human

Clone :

13F12F2

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Aliases :

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

more info or order :

Invitrogen product webpage