This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TGF beta-1,2,3 Monoclonal Antibody (1D11.16.8), Functional Grade, eBioscience
catalog :
16-9243-85
quantity :
500 ug
price :
US 558.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1D11.16.8

The same clone is also sold as:
reactivity :
Chinese hamsters, human, mouse, rat, dogs, rhesus macaque
application :
immunohistochemistry, neutralization, immunohistochemistry - paraffin section
citations: 13
Reference
Xing Y, Ren Z, Jin R, Liu L, Pei J, Yu K. Therapeutic efficacy and mechanism of CD73-TGFβ dual-blockade in a mouse model of triple-negative breast cancer. Acta Pharmacol Sin. 2022;43:2410-2418 pubmed publisher
Tang J, Li Y, Liu B, Liang W, Hu S, Shi M, et al. Uncovering a Key Role of ETS1 on Vascular Abnormality in Glioblastoma. Pathol Oncol Res. 2021;27:1609997 pubmed publisher
Le B, Podszywalow Bartnicka P, Maifrede S, Sullivan Reed K, Nieborowska Skorska M, Golovine K, et al. TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment. Cell Rep. 2020;33:108221 pubmed publisher
Imura Y, Ando M, Kondo T, Ito M, Yoshimura A. CD19-targeted CAR regulatory T cells suppress B cell pathology without GvHD. JCI Insight. 2020;5: pubmed publisher
Wang Z, Zhao M, Yin J, Liu L, Hu L, Huang Y, et al. E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases. J Clin Invest. 2020;130:3717-3733 pubmed publisher
Wang K, Shi Y, Song Z, Wu B, Zhou C, Liu W, et al. Regulatory effect of rat bone marrow mesenchymal stem cells on Treg/Th17 immune balance in vitro. Mol Med Rep. 2020;21:2123-2130 pubmed publisher
Penny H, Sieow J, Adriani G, Yeap W, See Chi Ee P, San Luis B, et al. Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma. Oncoimmunology. 2016;5:e1191731 pubmed publisher
Kang J, Lee J, Chang J. Cholera Toxin Promotes Th17 Cell Differentiation by Modulating Expression of Polarizing Cytokines and the Antigen-Presenting Potential of Dendritic Cells. PLoS ONE. 2016;11:e0157015 pubmed publisher
Hirota K, Hashimoto M, Yoshitomi H, Tanaka S, Nomura T, Yamaguchi T, et al. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J Exp Med. 2007;204:41-7 pubmed
Anscher M, Thrasher B, Rabbani Z, Teicher B, Vujaskovic Z. Antitransforming growth factor-beta antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation. Int J Radiat Oncol Biol Phys. 2006;65:876-81 pubmed
Hojo M, Morimoto T, Maluccio M, Asano T, Morimoto K, Lagman M, et al. Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature. 1999;397:530-4 pubmed
Pankewycz O, Miao L, Isaacs R, Guan J, Pruett T, Haussmann G, et al. Increased renal tubular expression of transforming growth factor beta in human allografts correlates with cyclosporine toxicity. Kidney Int. 1996;50:1634-40 pubmed
Dasch J, Pace D, Waegell W, Inenaga D, Ellingsworth L. Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification. J Immunol. 1989;142:1536-41 pubmed
product information
Product Type :
Antibody
Product Name :
TGF beta-1,2,3 Monoclonal Antibody (1D11.16.8), Functional Grade, eBioscience
Catalog # :
16-9243-85
Quantity :
500 ug
Price :
US 558.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Canine, Hamster, Human, Mouse, Non-human primate, Rat, Rhesus Monkey
Applications :
Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Neutralization: Assay-Dependent
Species :
Canine, Hamster, Human, Mouse, Non-human primate, Rat, Rhesus Monkey
Clone :
1D11.16.8
Isotype :
IgG1
Storage :
4 C
Description :
TGF-beta1, -2, and -3 are a closely related group of proteins (70-80% sequence homology) that are produced by many cell types and function as growth and differentiation factors. The active forms of TGF-beta1, -2, and -3 are disulfide-linked homodimers.
Format :
Liquid
Applications w/Dilutions :
Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; tgf beta 1; tgf beta 3; tgf beta1; TGFB; Tgfb1; Tgfb-1; TGFB4; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; TGF-beta4; tissue growth factor-beta4; Transforming growth factor; transforming growth factor beta 1; transforming growth factor beta 4; transforming growth factor beta 4 precursor; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta-1 precursor
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA