CD200 Receptor Monoclonal Antibody (OX108), Functional Grade, eBioscience | Invitrogen 16-9201-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD200 Receptor Monoclonal Antibody (OX108), Functional Grade, eBioscience

catalog :

16-9201-82

quantity :

100 µg

price :

US 99.75

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OX108

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Caserta S, Nausch N, Sawtell A, Drummond R, Barr T, MacDonald A, et al. Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells. PLoS ONE. 2012;7:e35466 pubmed publisher
	Timmerman L, de Graaf J, Satravelas N, Kesmir x, Meyaard L, van der Vlist M. Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function. PLoS ONE. 2021;16:e0244770 pubmed publisher
	Li W, Katz B, Spinola S. Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages. Infect Immun. 2012;80:4426-34 pubmed publisher
	Ambarus C, Noordenbos T, de Hair M, Tak P, Baeten D. Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis. Arthritis Res Ther. 2012;14:R74 pubmed publisher
	Letarte M, Voulgaraki D, Hatherley D, Foster Cuevas M, Saunders N, Barclay A. Analysis of leukocyte membrane protein interactions using protein microarrays. BMC Biochem. 2005;6:2 pubmed
	Foster Cuevas M, Wright G, Puklavec M, Brown M, Barclay A. Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor. J Virol. 2004;78:7667-76 pubmed

product information

Product Type :

Antibody

Product Name :

CD200 Receptor Monoclonal Antibody (OX108), Functional Grade, eBioscience

Catalog # :

16-9201-82

Quantity :

100 µg

Price :

US 99.75

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Species :

Human

Clone :

OX108

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Aliases :

antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; CD200 R1; CD200 receptor 1; CD200R; Cd200r1; Cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; Orexin receptor 2; OX102 antigen; OX2 receptor; OX2R; UNQ2522/PRO6015

more info or order :

Invitrogen product webpage