CD268 (BAFF Receptor) Monoclonal Antibody (8A7), Functional Grade, eBioscience | Invitrogen 16-9117-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD268 (BAFF Receptor) Monoclonal Antibody (8A7), Functional Grade, eBioscience

catalog :

16-9117-82

quantity :

100 µg

price :

US 372

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8A7

reactivity :

human

application :

flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...	Li R, Rezk A, Miyazaki Y, Hilgenberg E, Touil H, Shen P, et al. Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy. Sci Transl Med. 2015;7:310ra166 pubmed publisher
immunohistochemistry - frozen section; human; 1:150; fig 3a-f	Di Niro R, Snir O, Kaukinen K, Yaari G, Lundin K, Gupta N, et al. Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease. Mucosal Immunol. 2016;9:254-64 pubmed publisher
flow cytometry; human; fig 2	Lehnhardt A, Strecker M, Eiermann T, Marget M, Thaiss F, Nashan B, et al. High B-cell activating factor is not associated with worse 3-year graft outcome in blood group-incompatible kidney transplantation with rituximab induction. Clin Transplant. 2015;29:359-64 pubmed publisher
	Wang X, Huang J, Zhang A, Fang C, Ma Q, Jiang P. Altered expression profile of BAFF receptors on peripheral blood B lymphocytes in Graves' disease. BMC Endocr Disord. 2021;21:88 pubmed publisher
	Hijano D, Siefker D, Shrestha B, Jaligama S, Vu L, Tillman H, et al. Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy. Sci Rep. 2018;8:11034 pubmed publisher
	Imbrechts M, De Samblancx K, Fierens K, Brisse E, Vandenhaute J, Mitera T, et al. IFN-γ stimulates CpG-induced IL-10 production in B cells via p38 and JNK signalling pathways. Eur J Immunol. 2018;48:1506-1521 pubmed publisher
	Lundell A, Nordström I, Andersson K, Lundqvist C, Telemo E, Nava S, et al. IFN type I and II induce BAFF secretion from human decidual stromal cells. Sci Rep. 2017;7:39904 pubmed publisher
	Zheng N, Wang D, Ming H, Zhang H, Yu X. BAFF promotes proliferation of human mesangial cells through interaction with BAFF-R. BMC Nephrol. 2015;16:72 pubmed publisher
	Bornacelly A, Mercado D, Acevedo N, Caraballo L. The strength of the antibody response to the nematode Ascaris lumbricoides inversely correlates with levels of B-Cell Activating Factor (BAFF). BMC Immunol. 2014;15:22 pubmed publisher
	Parameswaran R, MUSCHEN M, Kim Y, Groffen J, Heisterkamp N. A functional receptor for B-cell-activating factor is expressed on human acute lymphoblastic leukemias. Cancer Res. 2010;70:4346-56 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD268 (BAFF Receptor) Monoclonal Antibody (8A7), Functional Grade, eBioscience

Catalog # :

16-9117-82

Quantity :

100 µg

Price :

US 372

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent

Species :

Human

Clone :

8A7

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13. 1-q13. 31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent

Aliases :

2010006P15Rik; B cell-activating factor receptor; BAFF receptor; BAFFR; BAFF-R; B-cell maturation defect; B-cell maturation defect 1; B-cell-activating factor receptor; Bcmd; Bcmd1; Bcmd-1; BLyS receptor 3; BR3; BROMIX; CD268; CVID4; Lvis22; prolixin; RGD1560810; TNF receptor superfamily member 13C; Tnfrsf13c; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13C

more info or order :

Invitrogen product webpage