IL-13 Monoclonal Antibody (eBio1316H), Functional Grade, eBioscience | Invitrogen 16-7135-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-13 Monoclonal Antibody (eBio1316H), Functional Grade, eBioscience

catalog :

16-7135-025

quantity :

25 mg

price :

US 9310.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBio1316H

reactivity :

mouse

application :

neutralization

citations: 13

Reference
Donlan A, Sutherland T, Marie C, Preissner S, Bradley B, Carpenter R, et al. IL-13 is a driver of COVID-19 severity. JCI Insight. 2021;6: pubmed publisher
Donlan A, Sutherland T, Marie C, Preissner S, Bradley B, Carpenter R, et al. IL-13 is a driver of COVID-19 severity. medRxiv. 2021;: pubmed publisher
Radhakrishnan R, Thandi R, Tripathi D, Paidipally P, McAllister M, Mulik S, et al. BCG vaccination reduces the mortality of Mycobacterium tuberculosis-infected type 2 diabetes mellitus mice. JCI Insight. 2020;5: pubmed publisher
Dalmas E, Lehmann F, Dror E, Wueest S, Thienel C, Borsigova M, et al. Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production. Immunity. 2017;47:928-942.e7 pubmed publisher
Johnson R, Yu H, Strank N, Karunakaran K, Zhu Y, Brunham R. B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4?13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters. Infect Immun. 2018;86: pubmed publisher
Vicari A, Schoepfer A, Meresse B, Goffin L, Leger O, Josserand S, et al. Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. MAbs. 2017;9:927-944 pubmed publisher
Braune J, Weyer U, Hobusch C, Mauer J, Bruning J, Bechmann I, et al. IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity. J Immunol. 2017;198:2927-2934 pubmed publisher
de Kleer I, Kool M, de Bruijn M, Willart M, van Moorleghem J, Schuijs M, et al. Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung. Immunity. 2016;45:1285-1298 pubmed publisher
Drake L, Iijima K, Bartemes K, Kita H. Group 2 Innate Lymphoid Cells Promote an Early Antibody Response to a Respiratory Antigen in Mice. J Immunol. 2016;197:1335-42 pubmed publisher
Park S, Chen W, Esmaeil N, Lucas B, Marsh L, Reibman J, et al. Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution. Pulm Circ. 2014;4:654-68 pubmed publisher
Dahdah A, Gautier G, Attout T, Fiore F, Lebourdais E, Msallam R, et al. Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis. J Clin Invest. 2014;124:4577-89 pubmed publisher
Mahlios J, Zhuang Y. Contribution of IL-13 to early exocrinopathy in Id3-/- mice. Mol Immunol. 2011;49:227-33 pubmed publisher
Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, et al. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2. Am J Pathol. 2011;179:302-14 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-13 Monoclonal Antibody (eBio1316H), Functional Grade, eBioscience

Catalog # :

16-7135-025

Quantity :

25 mg

Price :

US 9310.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Functional Assay: Assay-Dependent, Immunostaining: Assay-dependent, Neutralization: Assay-Dependent

Species :

Mouse

Clone :

eBio1316H

Isotype :

IgG1, kappa

Storage :

4 C

Description :

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

Format :

Liquid

Applications w/Dilutions :

Functional Assay: Assay-Dependent, Immunostaining: Assay-dependent, Neutralization: Assay-Dependent

Aliases :

ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600