Published Application/Species/Sample/Dilution | Reference |
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- flow cytometry; mouse; loading ...; fig 4
| Kim K, Lee J, Ahn S, Won R, Kim S, Jeong S, et al. The methanol extract of Guettarda speciosa Linn. Ameliorates acute lung injury in mice. BMC Complement Med Ther. 2020;20:40 pubmed publisher
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| Smith K, Filbey K, Reynolds L, Hewitson J, Harcus Y, Boon L, et al. Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths. Mucosal Immunol. 2016;9:428-43 pubmed publisher
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- flow cytometry; mouse; fig 5
- ELISA; mouse
| Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher
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- flow cytometry; mouse; fig 2
| Zhang Y, Wu B, Metelli A, Thaxton J, Hong F, Rachidi S, et al. GP96 is a GARP chaperone and controls regulatory T cell functions. J Clin Invest. 2015;125:859-69 pubmed publisher
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- flow cytometry; mouse; fig 1
| Mehta P, Nuotio Antar A, Smith C. γδ T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice. J Leukoc Biol. 2015;97:121-34 pubmed publisher
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- flow cytometry; mouse; fig 1
| Lu M, Varley A, Munford R. Persistently active microbial molecules prolong innate immune tolerance in vivo. PLoS Pathog. 2013;9:e1003339 pubmed publisher
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| Hemmers S, Teijaro J, Arandjelovic S, Mowen K. PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection. PLoS ONE. 2011;6:e22043 pubmed publisher
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| Nijnik A, Madera L, Ma S, Waldbrook M, Elliott M, Easton D, et al. Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J Immunol. 2010;184:2539-50 pubmed publisher
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- flow cytometry; mouse; fig 4A
| Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed
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| Li D, Huang L, Kan R, Meng X, Wang S, Zou H, et al. LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis. Nat Commun. 2023;14:4436 pubmed publisher
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| Long F, Bhatti M, Kellenberger A, Sun W, Modica S, H xf6 ring M, et al. A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice. Mol Metab. 2023;69:101675 pubmed publisher
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| Cheng N, Kim K, Lau L. Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2. JCI Insight. 2022;7: pubmed publisher
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| Chen D, Jia G, Zhang Y, Mao H, Zhao L, Li W, et al. Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis. J Neuroinflammation. 2022;19:59 pubmed publisher
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| Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, et al. Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression. Nat Commun. 2022;13:897 pubmed publisher
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| Luo Y, Guo J, Jia W, Wu M, Yin F, Niu G, et al. TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization. Oxid Med Cell Longev. 2021;2021:3877617 pubmed publisher
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| Lee G, Liao T, Wu J, Wu K, Kuo C. Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE-/- mice fed high fat diet. J Biomed Sci. 2021;28:74 pubmed publisher
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| Zhou Z, Choi J, Shin J, Kim D, Kweon B, Oh H, et al. Betulinic Acid Ameliorates the Severity of Acute Pancreatitis via Inhibition of the NF-κB Signaling Pathway in Mice. Int J Mol Sci. 2021;22: pubmed publisher
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| Rupert J, Narasimhan A, Jengelley D, Jiang Y, Liu J, Au E, et al. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia. J Exp Med. 2021;218: pubmed publisher
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| Alford M, Choi K, Trimble M, Masoudi H, Kalsi P, Pletzer D, et al. Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies. Front Cell Infect Microbiol. 2021;11:621081 pubmed publisher
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| Ghergurovich J, García Cañaveras J, Wang J, Schmidt E, Zhang Z, Teslaa T, et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020;16:731-739 pubmed publisher
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| Bottek J, Soun C, Lill J, Dixit A, Thiebes S, Beerlage A, et al. Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder. Mucosal Immunol. 2020;13:702-714 pubmed publisher
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| Yeh C, Wu J, Lee G, Wen H, Lin P, Kuo C. Vanadium Derivative Exposure Promotes Functional Alterations of VSMCs and Consequent Atherosclerosis via ROS/p38/NF-κB-Mediated IL-6 Production. Int J Mol Sci. 2019;20: pubmed publisher
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| Mielke L, Liao Y, Clemens E, Firth M, Duckworth B, Huang Q, et al. TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis. J Exp Med. 2019;: pubmed publisher
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| Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed publisher
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| Mora Cartín R, Gutiérrez Jiménez C, Alfaro Alarcón A, Chaves Olarte E, Chacón Díaz C, Barquero Calvo E, et al. Neutrophils Dampen Adaptive Immunity in Brucellosis. Infect Immun. 2019;87: pubmed publisher
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| Düsedau H, Kleveman J, Figueiredo C, Biswas A, Steffen J, Kliche S, et al. p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation. Glia. 2019;67:193-211 pubmed publisher
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| Gubernatorova E, Gorshkova E, Namakanova O, Zvartsev R, Hidalgo J, Drutskaya M, et al. Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation. Front Immunol. 2018;9:2718 pubmed publisher
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| Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed publisher
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| Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, et al. Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation. J Allergy Clin Immunol. 2018;142:1894-1908.e7 pubmed publisher
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| Meier L, Auger J, Engelson B, Cowan H, Breed E, Gonzalez Torres M, et al. CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis. Circulation. 2018;137:2478-2493 pubmed publisher
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| Sheng L, Jena P, Hu Y, Liu H, Nagar N, Kalanetra K, et al. Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation. J Pathol. 2017;243:431-441 pubmed publisher
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| Jin W, Shi S, Li Z, Li M, Wood K, Gonzales R, et al. Depletion of microglia exacerbates postischemic inflammation and brain injury. J Cereb Blood Flow Metab. 2017;37:2224-2236 pubmed publisher
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| Zamarron B, Mergian T, Cho K, Martinez Santibañez G, Luan D, Singer K, et al. Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice. Diabetes. 2017;66:392-406 pubmed publisher
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| Pangrazzi L, Meryk A, Naismith E, Koziel R, Lair J, Krismer M, et al. "Inflamm-aging" influences immune cell survival factors in human bone marrow. Eur J Immunol. 2017;47:481-492 pubmed publisher
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| Nagashima H, Okuyama Y, Hayashi T, Ishii N, So T. TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development. J Immunol. 2016;196:4082-9 pubmed publisher
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| Nullens S, Staessens M, Peleman C, Plaeke P, Malhotra Kumar S, Francque S, et al. Beneficial Effects of Anti-Interleukin-6 Antibodies on Impaired Gastrointestinal Motility, Inflammation and Increased Colonic Permeability in a Murine Model of Sepsis Are Most Pronounced When Administered in a Preventive Setup. PLoS ONE. 2016;11:e0152914 pubmed publisher
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| Han Y, Choi J, Uyangaa E, Kim S, Kim J, Kim B, et al. Distinct dictation of Japanese encephalitis virus-induced neuroinflammation and lethality via triggering TLR3 and TLR4 signal pathways. PLoS Pathog. 2014;10:e1004319 pubmed publisher
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| Samuelson E, Laird R, Papillion A, Tatum A, Princiotta M, Hayes S. Reduced B lymphoid kinase (Blk) expression enhances proinflammatory cytokine production and induces nephrosis in C57BL/6-lpr/lpr mice. PLoS ONE. 2014;9:e92054 pubmed publisher
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| Macia A, Vaquero M, Gou Fabregas M, Castelblanco E, Valdivielso J, Anerillas C, et al. Sprouty1 induces a senescence-associated secretory phenotype by regulating NF?B activity: implications for tumorigenesis. Cell Death Differ. 2014;21:333-43 pubmed publisher
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| Namjoshi D, Martin G, Donkin J, Wilkinson A, Stukas S, Fan J, et al. The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. PLoS ONE. 2013;8:e53529 pubmed publisher
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| Yee N, Hamerman J. ?(2) integrins inhibit TLR responses by regulating NF-?B pathway and p38 MAPK activation. Eur J Immunol. 2013;43:779-92 pubmed publisher
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| Tang G, Zhou H, Xu J, Xu J, Ji M, Wu H, et al. Schistosoma japonicum soluble egg antigens attenuate IFN-?-induced MHC class II expression in RAW 264.7 macrophages. PLoS ONE. 2012;7:e49234 pubmed publisher
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| Osterbur J, Sprague L, Muccioli M, Pate M, Mansfield K, McGinty J, et al. Adhesion to substrates induces dendritic cell endothelization and decreases immunological response. Immunobiology. 2013;218:64-75 pubmed publisher
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| Huang G, Wang Y, Shi L, Kanneganti T, Chi H. Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates. Immunity. 2011;35:45-58 pubmed publisher
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| Lal G, Yin N, Xu J, Lin M, Schroppel S, Ding Y, et al. Distinct inflammatory signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function. Am J Transplant. 2011;11:203-14 pubmed publisher
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| Levy D, Kuo A, Chang Y, Schaefer U, Kitson C, Cheung P, et al. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol. 2011;12:29-36 pubmed publisher
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| Wu Y, El Shikh M, El Sayed R, Best A, Szakal A, Tew J. IL-6 produced by immune complex-activated follicular dendritic cells promotes germinal center reactions, IgG responses and somatic hypermutation. Int Immunol. 2009;21:745-56 pubmed publisher
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| Maynard C, Hatton R, Helms W, Oliver J, Stephensen C, Weaver C. Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells. J Exp Med. 2009;206:343-57 pubmed publisher
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| Kielar M, John R, Bennett M, Richardson J, Shelton J, Chen L, et al. Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol. 2005;16:3315-25 pubmed
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