Asialo GM1 Polyclonal Antibody, Functional Grade, eBioscience | Invitrogen 16-6507-39 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Asialo GM1 Polyclonal Antibody, Functional Grade, eBioscience

catalog :

16-6507-39

quantity :

1 mg

price :

US 666.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

immunocytochemistry, flow cytometry

citations: 5

Reference
Cheng C, Zhang Q, Li Y, Jiang J, Xie L, Shen H, et al. Interplay Between Liver Type 1 Innate Lymphoid Cells and NK Cells Drives the Development of Alcoholic Steatohepatitis. Cell Mol Gastroenterol Hepatol. 2023;15:261-274 pubmed publisher
Ong L, Lee W, Ma S, Oguz G, Niu Z, Bao Y, et al. IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer. Proc Natl Acad Sci U S A. 2022;119:e2201376119 pubmed publisher
Qadir A, Guegan J, Ginestier C, Chaibi A, Bessede A, Charafe Jauffret E, et al. CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells. iScience. 2021;24:103348 pubmed publisher
Mingozzi F, Spreafico R, Gorletta T, Cigni C, Di Gioia M, Caccia M, et al. Prolonged contact with dendritic cells turns lymph node-resident NK cells into anti-tumor effectors. EMBO Mol Med. 2016;8:1039-51 pubmed publisher
Tuohy V, Jaini R, Johnson J, Loya M, Wilk D, Downs Kelly E, et al. Targeted Vaccination against Human ?-Lactalbumin for Immunotherapy and Primary Immunoprevention of Triple Negative Breast Cancer. Cancers (Basel). 2016;8: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Asialo GM1 Polyclonal Antibody, Functional Grade, eBioscience

Catalog # :

16-6507-39

Quantity :

1 mg

Price :

US 666.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Rabbit

Reactivity :

Bovine, Hamster, Human, Mouse, Rat

Applications :

Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: Assay-Dependent

Species :

Bovine, Hamster, Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C

Description :

Asialo ganglio-N-tetraosylceramide (asialo-GM1) is a glycolipid on human, mouse, rat, bovine and hamster cells. Glycolipids such as this sialyated version are defined by the specific transferases that modify the lipid. Glycolipids are targets of immune cell response. Auto-antibodies have also been identified. Additionally these glycolipids can act as co-receptors for pathogens. Asialo-GM1 is present on both NK cells and a subset of monocyte/macrophages from the mouse spleen. Expression is also found on rat and bovine brain, fetal liver and on fetal immature thymocytes. Expression has also been shown to increase with tumor progression.

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: Assay-Dependent

Aliases :

AsialoGM1