CD275 (B7-H2) Monoclonal Antibody (HK5.3), Functional Grade, eBioscience | Invitrogen 16-5985-85 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD275 (B7-H2) Monoclonal Antibody (HK5.3), Functional Grade, eBioscience

catalog :

16-5985-85

quantity :

500 µg

price :

US 490

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

HK5.3

reactivity :

human, mouse

application :

neutralization, flow cytometry

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s6	Cortes J, Ambesi Impiombato A, Couronné L, Quinn S, Kim C, da Silva Almeida A, et al. RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cancer Cell. 2018;33:259-273.e7 pubmed publisher
flow cytometry; mouse; loading ...; fig 5a	Inoue T, Shinnakasu R, Ise W, Kawai C, Egawa T, Kurosaki T. The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help. J Exp Med. 2017;214:1181-1198 pubmed publisher
flow cytometry; mouse; fig 2	Pizzolla A, Oh D, Luong S, Prickett S, Henstridge D, Febbraio M, et al. High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance. PLoS ONE. 2016;11:e0160407 pubmed publisher
flow cytometry; mouse; fig 2c	Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed publisher
flow cytometry; human; fig 3	Hannani D, VÃ©tizou M, Enot D, Rusakiewicz S, Chaput N, Klatzmann D, et al. Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25. Cell Res. 2015;25:208-24 pubmed publisher
flow cytometry; mouse; fig 5b	Kanzato H, Fujiwara S, Ise W, Kaminogawa S, Sato R, Hachimura S. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function. Immunobiology. 2008;213:399-408 pubmed publisher
flow cytometry; mouse; fig 1	Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed
flow cytometry; mouse	Smith P, Walsh C, Mangan N, Fallon R, Sayers J, McKenzie A, et al. Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol. 2004;173:1240-8 pubmed
	Oseledchyk A, Ricca J, Gigoux M, Ko B, Redelman Sidi G, Walther T, et al. Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus. Oncotarget. 2018;9:28702-28716 pubmed publisher
	Zamarin D, Ricca J, Sadekova S, Oseledchyk A, Yu Y, Blumenschein W, et al. PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy. J Clin Invest. 2018;128:1413-1428 pubmed publisher
	Uto T, Takagi H, Fukaya T, Nasu J, Fukui T, Miyanaga N, et al. Critical role of plasmacytoid dendritic cells in induction of oral tolerance. J Allergy Clin Immunol. 2018;141:2156-2167.e9 pubmed publisher
	Li Y, Liu X, Duan W, Tian H, Zhu G, He H, et al. Batf3-dependent CD8?+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages. EBioMedicine. 2017;18:188-198 pubmed publisher
	Shao L, Lie A, Zhang Y, Wong C, Kwong Y. Aberrant germinal center formation, follicular T-helper cells, and germinal center B-cells were involved in chronic graft-versus-host disease. Ann Hematol. 2015;94:1493-504 pubmed publisher
	Gao X, Zhao L, Wang S, Yang J, Yang X. Enhanced inducible costimulator ligand (ICOS-L) expression on dendritic cells in interleukin-10 deficiency and its impact on T-cell subsets in respiratory tract infection. Mol Med. 2013;19:346-56 pubmed publisher
	Hausl C, Ahmad R, Schwarz H, Muchitsch E, Turecek P, Dorner F, et al. Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders. Blood. 2004;104:115-22 pubmed

product information

Product Type :

Antibody

Product Name :

CD275 (B7-H2) Monoclonal Antibody (HK5.3), Functional Grade, eBioscience

Catalog # :

16-5985-85

Quantity :

500 µg

Price :

US 490

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent

Species :

Mouse

Clone :

HK5.3

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand

more info or order :

Invitrogen product webpage