HLA-BC Monoclonal Antibody (B1.23.2), Functional Grade, eBioscience | Invitrogen 16-5935-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HLA-BC Monoclonal Antibody (B1.23.2), Functional Grade, eBioscience

catalog :

16-5935-82

quantity :

100 µg

price :

US 91.5

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B1.23.2

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Chiou S, Tseng D, Reuben A, Mallajosyula V, Molina I, Conley S, et al. Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery. Immunity. 2021;54:586-602.e8 pubmed publisher
	Ma Y, Liu F, Li B, Peng K, Zhou H, Xu Y, et al. Identification and assessment of TCR-T cells targeting an epitope conserved in SARS-CoV-2 variants for the treatment of COVID-19. Int Immunopharmacol. 2022;112:109283 pubmed publisher
	van der Ploeg K, Chang C, Ivarsson M, Moffett A, Wills M, Trowsdale J. Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells. Front Immunol. 2017;8:298 pubmed publisher
	O Connor G, Vivian J, Widjaja J, Bridgeman J, Gostick E, Lafont B, et al. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. J Immunol. 2014;192:2875-84 pubmed publisher
	Desfrançois J, Moreau Aubry A, Vignard V, Godet Y, Khammari A, Dreno B, et al. Double positive CD4CD8 alphabeta T cells: a new tumor-reactive population in human melanomas. PLoS ONE. 2010;5:e8437 pubmed publisher
	Achdout H, Manaster I, Mandelboim O. Influenza virus infection augments NK cell inhibition through reorganization of major histocompatibility complex class I proteins. J Virol. 2008;82:8030-7 pubmed publisher
	Rebai N, Malissen B. Structural and genetic analyses of HLA class I molecules using monoclonal xenoantibodies. Tissue Antigens. 1983;22:107-17 pubmed
	Srivastava R, Duceman B, Biro P, Sood A, Weissman S. Molecular organization of the class I genes of human major histocompatibility complex. Immunol Rev. 1985;84:93-121 pubmed

product information

Product Type :

Antibody

Product Name :

HLA-BC Monoclonal Antibody (B1.23.2), Functional Grade, eBioscience

Catalog # :

16-5935-82

Quantity :

100 µg

Price :

US 91.5

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Species :

Human

Clone :

B1.23.2

Isotype :

IgG2b, kappa

Storage :

4° C

Description :

HLA-class I antigens are widely distributed on human nucleated cells. The intensity of HLA-ABC maybe altered in pathological states e.g. malignant cells may lose HLA-ABC, whereas hepatocytes in alcoholic hepatitis, biliary cirrhosis and chronic active hepatitis may show enhanced expression of HLA-ABC. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Aliases :

AS; B-4901; B-5001; Bw-47; Bw-50; class I MHC, HLA-B antigen; epididymis secretory protein Li 83; HEL-S-83; histocompatibility antigen; HLA -B; HLA B-40011; HLA B44; HLA class I antigen HLA-B; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, B-47 alpha chain; HLA class I histocompatibility antigen, B-50 alpha chain; HLA class I histocompatibility antigen, B-82 alpha chain; HLA locus; HLA molecule; HLAB; HLA-B; HLA-B alpha chain; HLA-B alpha chain (B*2706); HLA-B alpha chain (B*5002); HLA-B alpha-chain; HLA-B*45ZJ; HLA-B15; HLA-B35; HLA-B35 antigen; HLA-B-3506; HLA-B39; HLA-B-3905; HLA-B49; HLA-B50; HLA-B55; HLA-B-5502; HLA-B-5602; HLA-B59; HLA-B61; HLA-Bw50 antigen; HLA-Cw; HLA-DRB1; hypothetical protein; lecocyte antigen B; Leukocyte Antigen; leukocyte antigen class I-B; Leukoocyte Antigen; lymphocyte antigen; major histocompatability complex B antigen; major histocompatibility complex, class I, B; MHC antigen; MHC class 1 antigen; MHC class I alpha chain; MHC class I anitgen; MHC class I antigen B*47; MHC class I antigen B*50; MHC class I antigen B*82; MHC class I antigen GN00104; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen SHCHA; MHC class I antigene; MHC class I human leukocyte antigen; MHC class I molecule; MHC class I protein; MHC class II antigen; MHC class l antigen; MHC classI antigen; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B27d; MHC HLA-B27-HS; MHC HLA-B39N; SPDA1; truncated class I antigen; truncated MHC class I antigen

more info or order :

Invitrogen product webpage