product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Functional Grade, eBioscience
catalog :
16-5931-82
quantity :
100 µg
price :
US 177.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RB6-8C5
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 749
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:50; fig 4b
Kumagai Y, Futoh Y, Miyato H, Ohzawa H, Yamaguchi H, Saito S, et al. Effect of Systemic or Intraperitoneal Administration of Anti-PD-1 Antibody for Peritoneal Metastases from Gastric Cancer. In Vivo. 2022;36:1126-1135 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Flamini S, Sergeev P, Viana de Barros Z, Mello T, Biagioli M, Paglialunga M, et al. Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment. Cell Death Dis. 2021;12:421 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4e
Cervantes P, Martorelli Di Genova B, Erazo Flores B, Knoll L. RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection. Infect Immun. 2021;89: pubmed publisher
  • flow cytometry; mouse
Park B, Shin M, Kim J, Park G, Ryu Y, Lee J, et al. Ectopic Expression of Human Thymosin β4 Confers Resistance to Legionella pneumophila during Pulmonary and Systemic Infection in Mice. Infect Immun. 2021;89: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Ricci B, Tycksen E, Celik H, Belle J, Fontana F, Civitelli R, et al. Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 3c
Azcutia V, Kelm M, Luissint A, Boerner K, Flemming S, Quirós M, et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Mei Y, Wang Z, Zhang Y, Wan T, Xue J, He W, et al. FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Ameliorates DSS-Induced Colitis Against Oxidative Stress by Activating Nrf2/HO-1 Pathway. Front Immunol. 2019;10:2969 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig e1a, e1c
Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s19c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher
  • flow cytometry; mouse; 1:1000; loading ...; fig e2j, 4g
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4f
Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Gubernatorova E, Gorshkova E, Namakanova O, Zvartsev R, Hidalgo J, Drutskaya M, et al. Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation. Front Immunol. 2018;9:2718 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Humblet Baron S, Barber J, Roca C, Lenaerts A, Koni P, Liston A. Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells. Blood. 2018;: pubmed publisher
  • flow cytometry; mouse; 1:75; loading ...; fig 3a
Kiang L, Ross B, Yao J, Shanmugam S, Andrews C, Hansen S, et al. Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci. 2018;59:3767-3778 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
Kim Y, Lee M, Gu H, Kim J, Jeong S, Yeo S, et al. HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Dis Model Mech. 2018;11: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1e
Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Takamori A, Nambu A, Sato K, Yamaguchi S, Matsuda K, Numata T, et al. IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity. Sci Rep. 2018;8:6639 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 8b
Westhorpe C, Norman M, Hall P, Snelgrove S, Finsterbusch M, Li A, et al. Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes. Nat Commun. 2018;9:747 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Supramaniam A, Liu X, Ferro V, Herrero L. Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice. Antimicrob Agents Chemother. 2018;62: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed publisher
  • blocking or activating experiments; mouse; fig s2
Hoggatt J, Singh P, Tate T, Chou B, Datari S, Fukuda S, et al. Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell. Cell. 2018;172:191-204.e10 pubmed publisher
  • flow cytometry; human; loading ...; fig s26e
Gopalakrishnan V, Spencer C, Nezi L, Reuben A, Andrews M, Karpinets T, et al. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science. 2018;359:97-103 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 4b
Larabee C, Desai S, Agasing A, Georgescu C, Wren J, Axtell R, et al. Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis. Mol Vis. 2016;22:1503-1513 pubmed
  • flow cytometry; mouse; loading ...; fig s3
  • immunohistochemistry; mouse; loading ...; fig 5a
Sharif S, Nakatani Y, Wise L, Corbett M, Real N, Stuart G, et al. A Broad-Spectrum Chemokine-Binding Protein of Bovine Papular Stomatitis Virus Inhibits Neutrophil and Monocyte Infiltration in Inflammatory and Wound Models of Mouse Skin. PLoS ONE. 2016;11:e0168007 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
  • flow cytometry; mouse
Bieber K, Witte M, Sun S, Hundt J, Kalies K, Dräger S, et al. T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita. Sci Rep. 2016;6:38357 pubmed publisher
  • flow cytometry; mouse; fig 6d
Stein S, Mack E, Rome K, Pajcini K, Ohtani T, Xu L, et al. Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL. PLoS ONE. 2016;11:e0155408 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3c
Song Z, Li Z, Li D, Fang W, Liu H, Yang D, et al. Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway. Sci Rep. 2016;6:25118 pubmed publisher
  • blocking or activating experiments; mouse; fig 7
Kocijancic D, Felgner S, Frahm M, Komoll R, Iljazovic A, Pawar V, et al. Therapy of solid tumors using probiotic Symbioflor-2: restraints and potential. Oncotarget. 2016;7:22605-22 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, et al. The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis. Nat Commun. 2016;7:10761 pubmed publisher
  • flow cytometry; mouse; loading ...
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
  • flow cytometry; mouse; fig 6
Gallego Ortega D, Ledger A, Roden D, Law A, Magenau A, Kikhtyak Z, et al. ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS Biol. 2015;13:e1002330 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Van Helden M, Goossens S, Daussy C, Mathieu A, Faure F, Marçais A, et al. Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection. J Exp Med. 2015;212:2015-25 pubmed publisher
  • flow cytometry; mouse; fig s2e
Alam M, Gaida M, Bergmann F, Lasitschka F, Giese T, Giese N, et al. Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression. Nat Med. 2015;21:1337-43 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
Hanot Mambres D, Machelart A, Vanderwinden J, De Trez C, Ryffel B, Letesson J, et al. In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice. PLoS ONE. 2015;10:e0137835 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2
Guo L, Huang Y, Chen X, Hu Li J, Urban J, Paul W. Innate immunological function of TH2 cells in vivo. Nat Immunol. 2015;16:1051-9 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed publisher
  • flow cytometry; mouse
Xu G, Wu H, Zhang J, Li D, Wang Y, Wang Y, et al. Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radic Biol Med. 2015;87:15-25 pubmed publisher
  • flow cytometry; mouse
Jacque E, Schweighoffer E, Tybulewicz V, Ley S. BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival. J Exp Med. 2015;212:883-92 pubmed publisher
  • flow cytometry; mouse
Berent Maoz B, Montecino Rodriguez E, Fice M, Casero D, Seet C, Crooks G, et al. The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS ONE. 2015;10:e0125414 pubmed publisher
  • flow cytometry; mouse; fig s1
Napier R, Norris B, Swimm A, Giver C, Harris W, Laval J, et al. Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity. PLoS Pathog. 2015;11:e1004770 pubmed publisher
  • flow cytometry; mouse; fig 3
Dal Secco D, Wang J, Zeng Z, Kolaczkowska E, Wong C, Petri B, et al. A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury. J Exp Med. 2015;212:447-56 pubmed publisher
  • flow cytometry; mouse; fig 3
Povinelli B, Kokolus K, Eng J, Dougher C, Curtin L, Capitano M, et al. Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells. PLoS ONE. 2015;10:e0120078 pubmed publisher
  • flow cytometry; mouse; fig 4e
Hu Lieskovan S, Mok S, Homet Moreno B, Tsoi J, Robert L, Goedert L, et al. Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma. Sci Transl Med. 2015;7:279ra41 pubmed publisher
  • flow cytometry; mouse; fig s2
Wiesner D, Specht C, Lee C, Smith K, Mukaremera L, Lee S, et al. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015;11:e1004701 pubmed publisher
  • flow cytometry; mouse; fig 2
Wensveen F, Jelenčić V, Valentić S, Šestan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher
  • flow cytometry; mouse; tbl s3
Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher
  • flow cytometry; mouse; fig 1
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • flow cytometry; mouse
Peng H, Li C, Kadow S, Henry B, Steinmann J, Becker K, et al. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. J Mol Med (Berl). 2015;93:675-89 pubmed publisher
  • blocking or activating experiments; mouse; fig 3b
  • flow cytometry; mouse
Du J, Shen X, Hu X, Sun B, Guan W, Li S, et al. Wip1-deficient neutrophils significantly promote intestinal ischemia/reperfusion injury in mice. Curr Mol Med. 2015;15:100-8 pubmed
  • flow cytometry; mouse; 0.4 ug/ml
Bergot A, Monnet N, Le Tran S, Mittal D, Al Kouba J, Steptoe R, et al. HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions. Immunol Cell Biol. 2015;93:540-7 pubmed publisher
  • flow cytometry; mouse; fig s2
Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
  • flow cytometry; mouse; fig 2
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed publisher
  • flow cytometry; mouse; fig s1
van Blijswijk J, Schraml B, Rogers N, Whitney P, Zelenay S, Acton S, et al. Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells. J Immunol. 2015;194:307-15 pubmed publisher
  • flow cytometry; mouse
McDonnell A, Lesterhuis W, Khong A, Nowak A, Lake R, Currie A, et al. Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy. Eur J Immunol. 2015;45:49-59 pubmed publisher
  • flow cytometry; mouse
Jacque E, Schweighoffer E, Visekruna A, Papoutsopoulou S, Janzen J, Zillwood R, et al. IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen. J Exp Med. 2014;211:2085-101 pubmed publisher
  • flow cytometry; mouse
Franklin B, Bossaller L, De Nardo D, Ratter J, Stutz A, Engels G, et al. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nat Immunol. 2014;15:727-37 pubmed publisher
  • flow cytometry; mouse
Geem D, Medina Contreras O, McBride M, Newberry R, Koni P, Denning T. Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes. J Immunol. 2014;193:431-8 pubmed publisher
  • flow cytometry; mouse; tbl 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  • flow cytometry; mouse
Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, et al. TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS Pathog. 2014;10:e1003900 pubmed publisher
  • flow cytometry; mouse
Gujar S, Clements D, Dielschneider R, Helson E, Marcato P, Lee P. Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms. Br J Cancer. 2014;110:83-93 pubmed publisher
  • flow cytometry; mouse; fig s6a
Redecke V, Wu R, Zhou J, Finkelstein D, Chaturvedi V, High A, et al. Hematopoietic progenitor cell lines with myeloid and lymphoid potential. Nat Methods. 2013;10:795-803 pubmed publisher
  • immunocytochemistry; mouse; 0.5 ug/ml
  • immunohistochemistry; mouse; 0.5 ug/ml
Martinod K, Demers M, Fuchs T, Wong S, Brill A, Gallant M, et al. Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice. Proc Natl Acad Sci U S A. 2013;110:8674-9 pubmed publisher
  • flow cytometry; mouse
Gerber S, Sedlacek A, Cron K, Murphy S, Frelinger J, Lord E. IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumor. Am J Pathol. 2013;182:2345-54 pubmed publisher
  • flow cytometry; mouse; tbl 1
Vink P, Smout W, Driessen Engels L, de Bruin A, Delsing D, Krajnc Franken M, et al. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation. PLoS ONE. 2013;8:e57348 pubmed publisher
  • flow cytometry; mouse
Koning J, Kooij G, de Vries H, Nolte M, Mebius R. Mesenchymal stem cells are mobilized from the bone marrow during inflammation. Front Immunol. 2013;4:49 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 7j
Kobayashi A, Donaldson D, Erridge C, Kanaya T, Williams I, Ohno H, et al. The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice. Mucosal Immunol. 2013;6:1027-37 pubmed publisher
  • flow cytometry; mouse
Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed publisher
  • flow cytometry; mouse
Qian B, Li J, Zhang H, Kitamura T, Zhang J, Campion L, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475:222-5 pubmed publisher
  • flow cytometry; mouse; tbl 1
Zavitz C, Bauer C, Gaschler G, Fraser K, Strieter R, Hogaboam C, et al. Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza. J Immunol. 2010;184:2001-13 pubmed publisher
  • flow cytometry; mouse; fig 9
Fahl S, Crittenden R, Allman D, Bender T. c-Myb is required for pro-B cell differentiation. J Immunol. 2009;183:5582-92 pubmed publisher
  • flow cytometry; mouse; fig 1
Guibal F, Alberich Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, et al. Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia. Blood. 2009;114:5415-25 pubmed publisher
  • flow cytometry; mouse
Zumsteg A, Baeriswyl V, Imaizumi N, Schwendener R, Ruegg C, Christofori G. Myeloid cells contribute to tumor lymphangiogenesis. PLoS ONE. 2009;4:e7067 pubmed publisher
  • flow cytometry; mouse; fig 1
Waskow C, Liu K, Darrasse Jèze G, Guermonprez P, Ginhoux F, Merad M, et al. The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat Immunol. 2008;9:676-83 pubmed publisher
  • flow cytometry; mouse
Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111:142-9 pubmed
  • flow cytometry; mouse; fig 3
Laurie K, Blundell M, Baxendale H, Howe S, Sinclair J, Qasim W, et al. Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector. Gene Ther. 2007;14:1623-31 pubmed
  • flow cytometry; mouse
van der Marel A, Samsom J, Greuter M, van Berkel L, O Toole T, Kraal G, et al. Blockade of IDO inhibits nasal tolerance induction. J Immunol. 2007;179:894-900 pubmed
  • flow cytometry; mouse; fig 2
Huang B, Zhao J, Shen S, Li H, He K, Shen G, et al. Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. Cancer Res. 2007;67:4346-52 pubmed
  • blocking or activating experiments; mouse
Fan J, Li Y, Vodovotz Y, Billiar T, Wilson M. Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2006;290:L738-L746 pubmed
Eislmayr K, Bestehorn A, Morelli L, Borroni M, Walle L, Lamkanfi M, et al. Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection. Sci Adv. 2022;8:eabj7293 pubmed publisher
Zheng Z, Li Y, Jia S, Zhu M, Cao L, Tao M, et al. Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3. Nat Commun. 2021;12:6202 pubmed publisher
Lewis E, Tulina N, Anton L, Brown A, Porrett P, Elovitz M. IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation. Front Immunol. 2021;12:741518 pubmed publisher
Abu El Maaty M, Grelet E, Keime C, Rerra A, Gantzer J, Emprou C, et al. Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions. Sci Adv. 2021;7: pubmed publisher
Manriquez V, Nivoit P, Urbina T, Echenique Rivera H, Melican K, Fernandez gerlinger M, et al. Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils. Nat Commun. 2021;12:4547 pubmed publisher
Sangaletti S, Botti L, Gulino A, Lecis D, Bassani B, Portararo P, et al. SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis. iScience. 2021;24:102510 pubmed publisher
Heindl S, Ricci A, Carofiglio O, Zhou Q, Arzberger T, Lénárt N, et al. Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies. J Exp Med. 2021;218: pubmed publisher
Glassman C, Su L, Majri Morrison S, Winkelmann H, Mo F, Li P, et al. Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist. elife. 2021;10: pubmed publisher
Lou Q, Zhao M, Xu Q, Xie S, Liang Y, Chen J, et al. Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma. Front Cell Dev Biol. 2021;9:658757 pubmed publisher
Trenevska I, Anderson A, Bentley C, Hassanali T, Wiblin S, Maguire S, et al. Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201. PLoS ONE. 2021;16:e0249967 pubmed publisher
Cohen A, Yang Z, Gnanapragasam P, Ou S, Dam K, Wang H, et al. Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers. PLoS ONE. 2021;16:e0247963 pubmed publisher
Cao Q, Huang Q, Wang Y, Li C. Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1. Theranostics. 2021;11:3527-3539 pubmed publisher
Bollenbach M, Nemska S, Wagner P, Camelin G, Daubeuf F, Obrecht A, et al. Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model. Molecules. 2021;26: pubmed publisher
Latif A, Newcombe A, Li S, Gilroy K, Robertson N, Lei X, et al. BRD4-mediated repression of p53 is a target for combination therapy in AML. Nat Commun. 2021;12:241 pubmed publisher
Kornstädt L, Pierre S, Weigert A, Ebersberger S, Schäufele T, Kolbinger A, et al. Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells. Front Immunol. 2020;11:607048 pubmed publisher
Lou F, Sun Y, Wang H. Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model. STAR Protoc. 2020;1:100115 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Functional Grade, eBioscience
Catalog # :
16-5931-82
Quantity :
100 µg
Price :
US 177.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent
Species :
Mouse
Clone :
RB6-8C5
Isotype :
IgG2b, kappa
Storage :
4° C
Description :
Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent
Aliases :
AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA