CD273 (B7-DC) Monoclonal Antibody (MIH18), Functional Grade, eBioscience™ | Invitrogen 16-5888-38 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD273 (B7-DC) Monoclonal Antibody (MIH18), Functional Grade, eBioscience™

catalog :

16-5888-38

quantity :

5 mg

price :

US 3100

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MIH18

reactivity :

human

application :

flow cytometry

citations: 7

Reference
Zheng B, Ren T, Huang Y, Sun K, Wang S, Bao X, et al. PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse. J Hematol Oncol. 2018;11:16 pubmed publisher
De Waele J, Marcq E, Van Audenaerde J, Van Loenhout J, Deben C, Zwaenepoel K, et al. Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade. Oncoimmunology. 2018;7:e1407899 pubmed publisher
Gulati N, SuÃ¡rez FariÃ±as M, Correa Da Rosa J, Krueger J. Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions. F1000Res. 2015;4:149 pubmed publisher
Braun N, Celada L, Herazo Maya J, Abraham S, Shaginurova G, Sevin C, et al. Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity. Am J Respir Crit Care Med. 2014;190:560-71 pubmed publisher
Bankey P, Banerjee S, Zucchiatti A, De M, Sleem R, Lin C, et al. Cytokine induced expression of programmed death ligands in human neutrophils. Immunol Lett. 2010;129:100-7 pubmed publisher
Fourcade J, Kudela P, Sun Z, Shen H, Land S, Lenzner D, et al. PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients. J Immunol. 2009;182:5240-9 pubmed publisher
Yang W, Li H, Chen P, Alizadeh H, He Y, Hogan R, et al. PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation. Invest Ophthalmol Vis Sci. 2009;50:273-80 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD273 (B7-DC) Monoclonal Antibody (MIH18), Functional Grade, eBioscience™

Catalog # :

16-5888-38

Quantity :

5 mg

Price :

US 3100

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Species :

Human

Clone :

MIH18

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [UniProt]

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Aliases :

B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; PDCD1LG2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2