CD314 (NKG2D) Monoclonal Antibody (MI-6 (MI6)), Functional Grade, eBioscience™ | Invitrogen 16-5880-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD314 (NKG2D) Monoclonal Antibody (MI-6 (MI6)), Functional Grade, eBioscience™

catalog :

16-5880-82

quantity :

100 µg

price :

199 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MI-6 (MI6)

reactivity :

mouse

application :

neutralization, flow cytometry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 2	Matsuda J, Zhang Q, Ndonye R, Richardson S, Howell A, Gapin L. T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood. 2006;107:2797-805 pubmed
	Sheppard S, Triulzi C, Ardolino M, Serna D, Zhang L, Raulet D, et al. Characterization of a novel NKG2D and NKp46 double-mutant mouse reveals subtle variations in the NK cell repertoire. Blood. 2013;121:5025-33 pubmed publisher
	Van Belle T, Ling E, Haase C, Bresson D, Ursø B, Von Herrath M. NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes. J Autoimmun. 2013;40:66-73 pubmed publisher
	Aust J, Gays F, Mickiewicz K, Buchanan E, Brooks C. The expression and function of the NKRP1 receptor family in C57BL/6 mice. J Immunol. 2009;183:106-16 pubmed publisher
	Whang M, Guerra N, Raulet D. Costimulation of dendritic epidermal gammadelta T cells by a new NKG2D ligand expressed specifically in the skin. J Immunol. 2009;182:4557-64 pubmed publisher
	Arina A, Murillo O, Dubrot J, Azpilikueta A, Gabari I, Perez Gracia J, et al. Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells. Gene Ther. 2008;15:473-83 pubmed publisher
	Walsh K, Lodoen M, Edwards R, Lanier L, Lane T. Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease. J Virol. 2008;82:3021-30 pubmed
	Arina A, Murillo O, Hervas Stubbs S, Azpilikueta A, Dubrot J, Tirapu I, et al. The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma. Int J Cancer. 2007;121:1282-95 pubmed
	Jamieson A, Diefenbach A, McMahon C, Xiong N, Carlyle J, Raulet D. The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity. 2002;17:19-29 pubmed

product information

Product Type :

Antibody

Product Name :

CD314 (NKG2D) Monoclonal Antibody (MI-6 (MI6)), Functional Grade, eBioscience™

Catalog # :

16-5880-82

Quantity :

100 µg

Price :

199 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent

Species :

Mouse

Clone :

MI-6 (MI6)

Isotype :

IgG2a, lambda

Storage :

4° C

Description :

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D

more info or order :

Invitrogen product webpage