CD314 (NKG2D) Monoclonal Antibody (1D11), Functional Grade, eBioscience | Invitrogen 16-5878-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD314 (NKG2D) Monoclonal Antibody (1D11), Functional Grade, eBioscience

catalog :

16-5878-050

quantity :

50 mg

price :

US 13750

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D11

reactivity :

human

application :

neutralization, flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...	Hood S, Cosma G, Foulds G, Johnson C, Reeder S, McArdle S, et al. Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data. elife. 2020;9: pubmed publisher
	Tang S, Fu H, Xu Q, Zhou Y. miR-20a regulates sensitivity of colorectal cancer cells to NK cells by targeting MICA. Biosci Rep. 2019;: pubmed publisher
	Groh V, Bruhl A, El Gabalawy H, Nelson J, Spies T. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2003;100:9452-7 pubmed

product information

Product Type :

Antibody

Product Name :

CD314 (NKG2D) Monoclonal Antibody (1D11), Functional Grade, eBioscience

Catalog # :

16-5878-050

Quantity :

50 mg

Price :

US 13750

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.06 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent

Species :

Human

Clone :

1D11

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.06 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D