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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MICA/B Monoclonal Antibody (6D4), Functional Grade, eBioscience™
catalog :
16-5788-85
quantity :
500 µg
price :
427 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6D4
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
  • immunohistochemistry; human
Ikeshita S, Miyatake Y, Otsuka N, Kasahara M. MICA/B expression in macrophage foam cells infiltrating atherosclerotic plaques. Exp Mol Pathol. 2014;97:171-5 pubmed publisher
Shimizu T, Tomogane M, Miyashita M, Ukimura O, Ashihara E. Low dose gemcitabine increases the cytotoxicity of human Vγ9Vδ2 T cells in bladder cancer cells in vitro and in an orthotopic xenograft model. Oncoimmunology. 2018;7:e1424671 pubmed publisher
Yin X, Lu X, Xiuwen Z, Min Z, Xiao R, Mao Z, et al. Role of NKG2D in cytokine-induced killer cells against lung cancer. Oncol Lett. 2017;13:3139-3143 pubmed publisher
Miyatake Y, Oliveira A, Jarboui M, Ota S, Tomaru U, Teshima T, et al. Protective roles of epithelial cells in the survival of adult T-cell leukemia/lymphoma cells. Am J Pathol. 2013;182:1832-42 pubmed publisher
Uzunel M, Kasimu H, Joshi M, Ge X, Liu J, Xu B, et al. Evidence for no relevance of anti-major histocompatibility complex class I-related chain a antibodies in liver transplantation. Liver Transpl. 2008;14:1793-802 pubmed publisher
product information
Product Type :
Antibody
Product Name :
MICA/B Monoclonal Antibody (6D4), Functional Grade, eBioscience™
Catalog # :
16-5788-85
Quantity :
500 µg
Price :
427 USD
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
Species :
Human
Clone :
6D4
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
Aliases :
HLA class I antigen; MHC class I chain-related protein A; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence B; MHC class I related sequence A; MHC class I-like molecule PERB11.2-IMX; MICA; MIC-A; MICB; MIC-B; PERB11.1; PERB11.2; sMICA; sMICB; soluble MICA; soluble MICB; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA