This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD85k (Gp49b) Monoclonal Antibody (H1.1), Functional Grade, eBioscience
catalog :
16-5784-85
quantity :
500 ug
price :
US 395.00
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
H1.1

The same clone is also sold as:
reactivity :
mouse
application :
neutralization
citations: 3
Reference
Harakal J, Rival C, Qiao H, Tung K. Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis. J Immunol. 2016;197:27-41 pubmed publisher
Gu X, Laouar A, Wan J, Daheshia M, Lieberman J, Yokoyama W, et al. The gp49B1 inhibitory receptor regulates the IFN-gamma responses of T cells and NK cells. J Immunol. 2003;170:4095-101 pubmed
Wang L, Chu D, Dokun A, Yokoyama W. Inducible expression of the gp49B inhibitory receptor on NK cells. J Immunol. 2000;164:5215-20 pubmed
product information
Product Type :
Antibody
Product Name :
CD85k (Gp49b) Monoclonal Antibody (H1.1), Functional Grade, eBioscience
Catalog # :
16-5784-85
Quantity :
500 ug
Price :
US 395.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Armenian Hamster
Reactivity :
Mouse
Applications :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
Species :
Mouse
Clone :
H1.1
Isotype :
IgG
Storage :
4 C
Description :
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Format :
Liquid
Applications w/Dilutions :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
CD85 antigen-like family member K; CD85K; glycoprotein 49 B; glycoprotein 49b; gp49; Gp49b; GP49B2; HM18; ILT3; ILT-3; Immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; leukocyte immunoglobulin like receptor B4; leukocyte immunoglobulin-like receptor 5; Leukocyte immunoglobulin-like receptor subfamily B member 4; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; leukocyte immunoglobulin-like receptor, subfamily B, member 4; leukocyte surface receptor; Lilrb4; LIR5; LIR-5; mast cell surface glycoprotein Gp49B; Monocyte inhibitory receptor HM18
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA