Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience™ | Invitrogen 16-5671-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience™

catalog :

16-5671-82

quantity :

100 µg

price :

330 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBio3C8 (3C8)

reactivity :

mouse

application :

flow cytometry, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; 1 ug/ml; loading ...; fig 7c	Chia J, Zhu T, Chyou S, Dasoveanu D, Carballo C, Tian S, et al. Dendritic cells maintain dermal adipose-derived stromal cells in skin fibrosis. J Clin Invest. 2016;126:4331-4345 pubmed publisher
	Lopes N, Charaix J, Cedile O, Serge A, Irla M. Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells. Nat Commun. 2018;9:1262 pubmed publisher
	Lopes N, Vachon H, Marie J, Irla M. Administration of RANKL boosts thymic regeneration upon bone marrow transplantation. EMBO Mol Med. 2017;9:835-851 pubmed publisher
	Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed publisher
	Xia X, Liu S, Xiao Z, Zhu F, Song N, Zhou M, et al. An IKKÎ±-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity. Cell Rep. 2013;5:1243-55 pubmed publisher
	Röhrl J, Huber B, Koehl G, Geissler E, Hehlgans T. Mouse ?-defensin 14 (Defb14) promotes tumor growth by inducing angiogenesis in a CCR6-dependent manner. J Immunol. 2012;188:4931-9 pubmed publisher
	Haybaeck J, Zeller N, Wolf M, Weber A, Wagner U, Kurrer M, et al. A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell. 2009;16:295-308 pubmed publisher
	Basak S, Kim H, Kearns J, Tergaonkar V, O Dea E, Werner S, et al. A fourth IkappaB protein within the NF-kappaB signaling module. Cell. 2007;128:369-81 pubmed
	Chin R, Lo J, Kim O, Blink S, Christiansen P, Peterson P, et al. Lymphotoxin pathway directs thymic Aire expression. Nat Immunol. 2003;4:1121-7 pubmed
	Nakamura T, Tashiro K, Nazarea M, Nakano T, Sasayama S, Honjo T. The murine lymphotoxin-beta receptor cDNA: isolation by the signal sequence trap and chromosomal mapping. Genomics. 1995;30:312-9 pubmed
	Crowe P, VanArsdale T, Walter B, Ware C, Hession C, Ehrenfels B, et al. A lymphotoxin-beta-specific receptor. Science. 1994;264:707-10 pubmed

product information

Product Type :

Antibody

Product Name :

Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience™

Catalog # :

16-5671-82

Quantity :

100 µg

Price :

330 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Species :

Mouse

Clone :

eBio3C8 (3C8)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Aliases :

AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; TNFRSF3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III

more info or order :

Invitrogen product webpage