Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience | Invitrogen 16-5671-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience

catalog :

16-5671-025

quantity :

25 mg

price :

US 8250

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBio3C8 (3C8)

reactivity :

mouse

application :

flow cytometry

citations: 9

Reference
Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, et al. Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses. Commun Biol. 2020;3:163 pubmed publisher
Piao W, Xiong Y, Li L, Saxena V, Smith K, Hippen K, et al. Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration. Cell Rep. 2020;30:1052-1062.e5 pubmed publisher
Lopes N, Charaix J, Cedile O, Serge A, Irla M. Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells. Nat Commun. 2018;9:1262 pubmed publisher
Lopes N, Vachon H, Marie J, Irla M. Administration of RANKL boosts thymic regeneration upon bone marrow transplantation. EMBO Mol Med. 2017;9:835-851 pubmed publisher
Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed publisher
Xia X, Liu S, Xiao Z, Zhu F, Song N, Zhou M, et al. An IKKÎ±-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity. Cell Rep. 2013;5:1243-55 pubmed publisher
Haybaeck J, Zeller N, Wolf M, Weber A, Wagner U, Kurrer M, et al. A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell. 2009;16:295-308 pubmed publisher
Basak S, Kim H, Kearns J, Tergaonkar V, O Dea E, Werner S, et al. A fourth IkappaB protein within the NF-kappaB signaling module. Cell. 2007;128:369-81 pubmed
Hamaguchi I, Morisada T, Azuma M, Murakami K, Kuramitsu M, Mizukami T, et al. Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival. Blood. 2006;107:1207-13 pubmed

product information

Product Type :

Antibody

Product Name :

Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience

Catalog # :

16-5671-025

Quantity :

25 mg

Price :

US 8250

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Species :

Mouse

Clone :

eBio3C8 (3C8)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent

Aliases :

AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; Tnfrsf3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III