FR4 Monoclonal Antibody (eBioTH6), Functional Grade, eBioscience | Invitrogen 16-5446-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FR4 Monoclonal Antibody (eBioTH6), Functional Grade, eBioscience

catalog :

16-5446-025

quantity :

25 mg

price :

US 8250

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

eBioTH6

reactivity :

mouse

application :

immunoprecipitation, flow cytometry

citations: 1

Reference
Paul Heng M, Leong M, Cunningham E, Bunker D, Bremner K, Wang Z, et al. Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction. JCI Insight. 2018;3: pubmed publisher

product information

Product Type :

Antibody

Product Name :

FR4 Monoclonal Antibody (eBioTH6), Functional Grade, eBioscience

Catalog # :

16-5446-025

Quantity :

25 mg

Price :

US 8250

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Mouse

Clone :

eBioTH6

Isotype :

IgG2b, kappa

Storage :

4° C

Description :

FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

0910001L11Rik; C86255; Folate receptor 4; folate receptor 4 (delta); folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); folate receptor delta; Folate-binding protein 3; Folbp3; Folr4; FR-delta; IZUMO1 receptor protein JUNO; IZUMO1 receptor, JUNO; Izumo1r; Juno; probable folate receptor delta; sperm-egg fusion protein Juno