CD336 (NKp44) Monoclonal Antibody (44.189), Functional Grade, eBioscience | Invitrogen 16-3369-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD336 (NKp44) Monoclonal Antibody (44.189), Functional Grade, eBioscience

catalog :

16-3369-82

quantity :

100 ug

price :

US 255.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

44.189

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Yu H, Wang X, Li J, Ye Y, Wang D, Fang W, et al. Addition of BTK inhibitor orelabrutinib to rituximab improved anti-tumor effects in B cell lymphoma. Mol Ther Oncolytics. 2021;21:158-170 pubmed publisher
Cella M, Gamini R, Sécca C, Collins P, Zhao S, Peng V, et al. Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues. Nat Immunol. 2019;: pubmed publisher
Muller Durovic B, Grählert J, Devine O, Akbar A, Hess C. CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. Aging (Albany NY). 2019;11:724-740 pubmed publisher
Collins P, Cella M, Porter S, Li S, Gurewitz G, Hong H, et al. Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells. Cell. 2019;176:348-360.e12 pubmed publisher
Zaiatz Bittencourt V, Finlay D, Gardiner C. Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism. J Immunol. 2018;200:3934-3941 pubmed publisher
Cantoni C, Bottino C, Vitale M, Pessino A, Augugliaro R, Malaspina A, et al. NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily. J Exp Med. 1999;189:787-96 pubmed

product information

Product Type :

Antibody

Product Name :

CD336 (NKp44) Monoclonal Antibody (44.189), Functional Grade, eBioscience

Catalog # :

16-3369-82

Quantity :

100 ug

Price :

US 255.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 ug/test, Functional Assay: Assay-Dependent

Species :

Human

Clone :

44.189

Isotype :

IgG2b, kappa

Storage :

4 C

Description :

CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test, Functional Assay: Assay-Dependent

Aliases :

CD336; CD336 antigen; dJ149M18.1; LY95; lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; natural killer cell receptor; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKP44; NK-p44; NK-p44dJ149M18.1