CD226 (DNAM-1) Monoclonal Antibody (10E5), Functional Grade, eBioscience™ | Invitrogen 16-2261-85 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD226 (DNAM-1) Monoclonal Antibody (10E5), Functional Grade, eBioscience™

catalog :

16-2261-85

quantity :

500 µg

price :

US 485

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

10E5

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2	Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed publisher
flow cytometry; mouse; 1:150; fig s4	Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
	Li Z, Morman R, Hegermiller E, Sun M, Bartom E, Maienschein Cline M, et al. The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude. J Exp Med. 2021;218: pubmed publisher
	Akkaya B, Oya Y, Akkaya M, Al Souz J, Holstein A, Kamenyeva O, et al. Regulatory T cells mediate specific suppression by depleting peptide-MHC class II from dendritic cells. Nat Immunol. 2019;20:218-231 pubmed publisher
	Liu T, Zhang D, Zhang Y, Xu X, Zhou B, Fang L, et al. Blocking CD226 Promotes Allogeneic Transplant Immune Tolerance and Improves Skin Graft Survival by Increasing the Frequency of Regulatory T Cells in a Murine Model. Cell Physiol Biochem. 2018;45:2338-2350 pubmed publisher
	Shifrin N, Kissiov D, Ardolino M, Joncker N, Raulet D. Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness. J Immunol. 2016;197:4127-4136 pubmed publisher
	Tang M, Khan M, Croxford J, Tan K, Angeli V, Gasser S. The DNA damage response induces antigen presenting cell-like functions in fibroblasts. Eur J Immunol. 2014;44:1108-18 pubmed publisher
	Mizutani T, Neugebauer N, Putz E, Moritz N, Simma O, Zebedin Brandl E, et al. Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance. Oncoimmunology. 2012;1:1027-1037 pubmed
	Zhu J, Huang X, Yang Y. NKG2D is required for NK cell activation and function in response to E1-deleted adenovirus. J Immunol. 2010;185:7480-6 pubmed publisher
	Brady J, Carotta S, Thong R, Chan C, Hayakawa Y, Smyth M, et al. The interactions of multiple cytokines control NK cell maturation. J Immunol. 2010;185:6679-88 pubmed publisher
	Dardalhon V, Schubart A, Reddy J, Meyers J, Monney L, Sabatos C, et al. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. J Immunol. 2005;175:1558-65 pubmed

product information

Product Type :

Antibody

Product Name :

CD226 (DNAM-1) Monoclonal Antibody (10E5), Functional Grade, eBioscience™

Catalog # :

16-2261-85

Quantity :

500 µg

Price :

US 485

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Species :

Mouse

Clone :

10E5

Isotype :

IgG2b, kappa

Storage :

4° C

Description :

DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Aliases :

adhesion glycoprotein; BC051526; Cd226; CD226 antigen; CD226 molecule; DNAM 1; DNAM1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; platelet and T-cell activation antigen 1; Pta1; T lineage-specific activation antigen 1 antigen; TLiSA1

more info or order :

Invitrogen product webpage