CD154 (CD40 Ligand) Monoclonal Antibody (24-31), Functional Grade, eBioscience™ | Invitrogen 16-1548-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD154 (CD40 Ligand) Monoclonal Antibody (24-31), Functional Grade, eBioscience™

catalog :

16-1548-025

quantity :

25 mg

price :

US 7500.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

24-31

reactivity :

crab eating macaque, human

application :

neutralization, flow cytometry

citations: 6

Reference
Zhang F, Zhu Y, Fan G, Hu S. Photodynamic therapy reduces the inhibitory effect of osteosarcoma cells on dendritic cells by upregulating HSP70. Oncol Lett. 2018;16:5034-5040 pubmed publisher
Trotta L, Weigt K, Schinnerling K, Geelhaar Karsch A, Oelkers G, Biagi F, et al. Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease. Infect Immun. 2017;85: pubmed publisher
Shaw P, Weidinger C, Vaeth M, Luethy K, Kaech S, Feske S. CD4âº and CD8âº T cell-dependent antiviral immunity requires STIM1 and STIM2. J Clin Invest. 2014;124:4549-63 pubmed publisher
Clarke E, Williams N, Findlow J, Borrow R, Heyderman R, Finn A. Polysaccharide-specific memory B cells generated by conjugate vaccines in humans conform to the CD27+IgG+ isotype-switched memory B Cell phenotype and require contact-dependent signals from bystander T cells activated by bacterial proteins to differe. J Immunol. 2013;191:6071-83 pubmed publisher
Os A, Burgler S, Ribes A, Funderud A, Wang D, Thompson K, et al. Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013;4:566-77 pubmed publisher
Barchet W, Price J, Cella M, Colonna M, MacMillan S, Cobb J, et al. Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation. Blood. 2006;107:1497-504 pubmed

product information

Product Type :

Antibody

Product Name :

CD154 (CD40 Ligand) Monoclonal Antibody (24-31), Functional Grade, eBioscience™

Catalog # :

16-1548-025

Quantity :

25 mg

Price :

US 7500.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Cynomolgus Monkey, Human

Applications :

Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent

Species :

Cynomolgus Monkey, Human

Clone :

24-31

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; Cd40l; CD40-L; CD40LG; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; Tnfsf5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5