CD147 Monoclonal Antibody (RL73), Functional Grade, eBioscience | Invitrogen 16-1471-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD147 Monoclonal Antibody (RL73), Functional Grade, eBioscience

catalog :

16-1471-82

quantity :

100 µg

price :

US 207

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RL73

reactivity :

mouse

application :

immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 3c	Patrizz A, Doran S, Chauhan A, Ahnstedt H, Roy O Reilly M, Lai Y, et al. EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke. Aging (Albany NY). 2020;12:5121-5139 pubmed publisher
	Nguyen Y, Fujisawa M, Nguyen T, Suehara Y, Sakamoto T, Matsuoka R, et al. Tet2 deficiency in immune cells exacerbates tumor progression by increasing angiogenesis in a lung cancer model. Cancer Sci. 2021;112:4931-4943 pubmed publisher
	Luan J, Zhao Y, Zhang Y, Miao J, Li J, Chen Z, et al. CD147 blockade as a potential and novel treatment of graft rejection. Mol Med Rep. 2017;16:4593-4602 pubmed publisher
	Byrne S, Ortiz L, Mali P, Aach J, Church G. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Res. 2015;43:e21 pubmed publisher
	Liu H, Yang L, Guo R, Zhu G, Shi Y, Wang X, et al. Functional blockage of EMMPRIN ameliorates atherosclerosis in apolipoprotein E-deficient mice. Int J Cardiol. 2013;168:3248-53 pubmed publisher
	Agrawal S, Silva C, Wang J, Tong J, Yong V. A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis. J Neuroinflammation. 2012;9:64 pubmed publisher
	Kasler H, Young B, Mottet D, Lim H, Collins A, Olson E, et al. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J Immunol. 2011;186:4782-93 pubmed publisher
	Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD147 Monoclonal Antibody (RL73), Functional Grade, eBioscience

Catalog # :

16-1471-82

Quantity :

100 µg

Price :

US 207

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Control: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Mouse

Clone :

RL73

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383

more info or order :

Invitrogen product webpage