product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD105 (Endoglin) Monoclonal Antibody (SN6), Functional Grade, eBioscience
catalog :
16-1057-82
quantity :
100 µg
price :
US 284
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SN6
reactivity :
baboons, human, cat
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 67
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:500; loading ...; fig 2e
Shao Q, Esseltine J, Huang T, Novielli Kuntz N, Ching J, SAMPSON J, et al. Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. Biomolecules. 2019;9: pubmed publisher
  • flow cytometry; human; fig s1a
Vernot J, Bonilla X, Rodriguez Pardo V, Vanegas N. Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment. Int J Mol Sci. 2017;18: pubmed publisher
  • flow cytometry; human; loading ...; tbl 1
Monsuur H, Weijers E, Niessen F, Gefen A, Koolwijk P, Gibbs S, et al. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering. PLoS ONE. 2016;11:e0167056 pubmed publisher
  • flow cytometry; cat; fig 2
Arzi B, Mills Ko E, Verstraete F, Kol A, Walker N, Badgley M, et al. Therapeutic Efficacy of Fresh, Autologous Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats. Stem Cells Transl Med. 2016;5:75-86 pubmed publisher
  • immunocytochemistry; human; fig 2
Ali H, Al Yatama M, Abu Farha M, Behbehani K, Al Madhoun A. Multi-lineage differentiation of human umbilical cord Wharton's Jelly Mesenchymal Stromal Cells mediates changes in the expression profile of stemness markers. PLoS ONE. 2015;10:e0122465 pubmed publisher
  • flow cytometry; baboons
Shi Q, Hodara V, Meng Q, Voruganti V, Rice K, Michalek J, et al. Early endothelial damage detected by circulating particles in baboons fed a diet high in simple carbohydrates in conjunction with saturated or unsaturated fat. Am J Cardiovasc Dis. 2014;4:123-32 pubmed
  • flow cytometry; human; fig 3
Rogacev K, Zawada A, Hundsdorfer J, Achenbach M, Held G, Fliser D, et al. Immunosuppression and monocyte subsets. Nephrol Dial Transplant. 2015;30:143-53 pubmed publisher
Liu P, Zhang Q, Mi J, Wang S, Xu Q, Zhuang D, et al. Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246. Stem Cell Res Ther. 2022;13:89 pubmed publisher
Park H, Choi J, Nam M, Seo Y. Induced Neurodifferentiation of hBM-MSCs through Activation of the ERK/CREB Pathway via Pulsed Electromagnetic Fields and Physical Stimulation Promotes Neurogenesis in Cerebral Ischemic Models. Int J Mol Sci. 2022;23: pubmed publisher
Azandeh S, Moghadam M, Rashno M, Zargar M, Zadeh P. The Effect of Different Doses of Melatonin on in Vitro Maturation of Human Follicular Fluid-Derived Oocyte-Like Cells. JBRA Assist Reprod. 2022;26:288-298 pubmed publisher
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R. TRPA1 triggers hyperalgesia and inflammation after tooth bleaching. Sci Rep. 2021;11:17418 pubmed publisher
Gao Y, Li W, Bu X, Xu Y, Cai S, Zhong J, et al. Human Amniotic Mesenchymal Stem Cells Inhibit aGVHD by Regulating Balance of Treg and T Effector Cells. J Inflamm Res. 2021;14:3985-3999 pubmed publisher
Li Y, Shi G, Han Y, Shang H, Li H, Liang W, et al. Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model. Stem Cell Res Ther. 2021;12:407 pubmed publisher
Güney Esken G, Erol Ö, Pervin B, Gürhan Sevinç G, Onder T, Bilgiç E, et al. Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells. Stem Cell Res Ther. 2021;12:287 pubmed publisher
Liu J, Qiu X, Lv Y, Zheng C, Dong Y, Dou G, et al. Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages. Stem Cell Res Ther. 2020;11:507 pubmed publisher
Gasiūnienė M, Valatkaitė E, Navakauskaitė A, Navakauskiene R. The Effect of Angiotensin II, Retinoic Acid, EGCG, and Vitamin C on the Cardiomyogenic Differentiation Induction of Human Amniotic Fluid-Derived Mesenchymal Stem Cells. Int J Mol Sci. 2020;21: pubmed publisher
Luzuriaga J, Irurzun J, Irastorza I, Unda F, Ibarretxe G, Pineda J. Vasculogenesis from Human Dental Pulp Stem Cells Grown in Matrigel with Fully Defined Serum-Free Culture Media. Biomedicines. 2020;8: pubmed publisher
Zhao A, Shah K, Freitag J, Cromer B, Sumer H. Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia. Stem Cells Int. 2020;2020:8898221 pubmed publisher
Sun L, Zhu W, Zhao P, Zhang J, Lu Y, Zhu Y, et al. Down-Regulated Exosomal MicroRNA-221 - 3p Derived From Senescent Mesenchymal Stem Cells Impairs Heart Repair. Front Cell Dev Biol. 2020;8:263 pubmed publisher
Hu H, Ji Q, Song M, Ren J, Liu Z, Wang Z, et al. ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. Nucleic Acids Res. 2020;48:6001-6018 pubmed publisher
Deng Q, Huang S, Wen J, Jiao Y, Su X, Shi G, et al. PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice. Stem Cell Res Ther. 2020;11:143 pubmed publisher
Yuan J, Wang X, Ma D, Gao H, Zheng D, Zhang J. Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway. Mol Med Rep. 2020;21:2085-2094 pubmed publisher
Rim Y, Nam Y, Park N, Jung H, Lee K, Lee J, et al. Chondrogenic Differentiation from Induced Pluripotent Stem Cells Using Non-Viral Minicircle Vectors. Cells. 2020;9: pubmed publisher
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, et al. Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro. Stem Cells Int. 2019;2019:8035076 pubmed publisher
Huang J, Wang Y, Lo S, Tseng L, Chen D, Wu Y, et al. Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer. Cancers (Basel). 2019;12: pubmed publisher
Fan C, Ji Q, Zhang C, Xu S, Sun H, Li Z. TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production. Mol Med Rep. 2019;20:3123-3130 pubmed publisher
Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, et al. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. Nat Commun. 2019;10:3329 pubmed publisher
Wang S, Min Z, Ji Q, Geng L, Su Y, Liu Z, et al. Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction. Protein Cell. 2019;: pubmed publisher
Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu F, et al. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis. PLoS Biol. 2019;17:e3000201 pubmed publisher
Zhang X, Liu Z, Liu X, Wang S, Zhang Y, He X, et al. Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis. Protein Cell. 2019;: pubmed publisher
Blackshear C, Borrelli M, Shen E, Ransom R, Chung N, Vistnes S, et al. Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue. Tissue Eng Part C Methods. 2018;: pubmed publisher
Geng L, Liu Z, Zhang W, Li W, Wu Z, Wang W, et al. Chemical screen identifies a geroprotective role of quercetin in premature aging. Protein Cell. 2019;10:417-435 pubmed publisher
Madhav A, Andres A, Duong F, Mishra R, Haldar S, Liu Z, et al. Antagonizing CD105 enhances radiation sensitivity in prostate cancer. Oncogene. 2018;37:4385-4397 pubmed publisher
Wu Z, Zhang W, Song M, Wang W, Wei G, Li W, et al. Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome. Protein Cell. 2018;9:333-350 pubmed publisher
Wang S, Hu B, Ding Z, Dang Y, Wu J, Li D, et al. ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Cell Discov. 2018;4:2 pubmed publisher
Yuan C, Pu L, He Z, Wang J. BNIP3/Bcl-2-mediated apoptosis induced by cyclic tensile stretch in human cartilage endplate-derived stem cells. Exp Ther Med. 2018;15:235-241 pubmed publisher
Jin Y, Muhl L, Burmakin M, Wang Y, Duchez A, Betsholtz C, et al. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling. Nat Cell Biol. 2017;19:639-652 pubmed publisher
Clark K, Fierro F, Ko E, Walker N, Arzi B, Tepper C, et al. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome. Stem Cell Res Ther. 2017;8:69 pubmed publisher
Li J, Mao Q, He J, She H, Zhang Z, Yin C. Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism. Stem Cell Res Ther. 2017;8:55 pubmed publisher
Webber B, Osborn M, McElroy A, Twaroski K, Lonetree C, Defeo A, et al. CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa. NPJ Regen Med. 2016;1: pubmed publisher
Park N, Rim Y, Jung H, Kim J, Yi H, Kim Y, et al. Etanercept-Synthesising Mesenchymal Stem Cells Efficiently Ameliorate Collagen-Induced Arthritis. Sci Rep. 2017;7:39593 pubmed publisher
Siavashi V, Asadian S, Taheri Asl M, Babaei H, Keshavarz S, Bazaei M, et al. The Improvement of Respiratory Performance After Phototherapy-Induced EPC Mobilization in Preterm Infants With RDS. J Cell Biochem. 2017;118:594-604 pubmed publisher
Yao Y, Deng Q, Song W, Zhang H, Li Y, Yang Y, et al. MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia. Stem Cell Reports. 2016;7:249-62 pubmed publisher
Siavashi V, Asadian S, Sharifi A, Esmaeilivand M, Norouzinia R, Azadbakht M, et al. Circulation Enrichment of Functional Endothelial Progenitor Cells by Infantile Phototherapy. J Cell Biochem. 2017;118:330-340 pubmed publisher
Agarwal S, Loder S, Sorkin M, Li S, Shrestha S, Zhao B, et al. Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification. Stem Cells. 2016;34:1692-701 pubmed publisher
Zou L, Chen Q, Quanbeck Z, Bechtold J, Kaufman D. Angiogenic activity mediates bone repair from human pluripotent stem cell-derived osteogenic cells. Sci Rep. 2016;6:22868 pubmed publisher
Nakamura T, Hosoyama T, Kawamura D, Takeuchi Y, Tanaka Y, Samura M, et al. Influence of aging on the quantity and quality of human cardiac stem cells. Sci Rep. 2016;6:22781 pubmed publisher
Zhu N, Wang H, Wang B, Wei J, Shan W, Feng J, et al. A Member of the Nuclear Receptor Superfamily, Designated as NR2F2, Supports the Self-Renewal Capacity and Pluripotency of Human Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells Int. 2016;2016:5687589 pubmed publisher
Loder S, Agarwal S, Sorkin M, Breuler C, Li J, Peterson J, et al. Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification. Ann Surg. 2016;264:1174-1180 pubmed
Pan H, Guan D, Liu X, Li J, Wang L, Wu J, et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res. 2016;26:190-205 pubmed publisher
Parys M, Nelson N, Koehl K, Miller R, Kaneene J, Kruger J, et al. Safety of Intraperitoneal Injection of Adipose Tissue-Derived Autologous Mesenchymal Stem Cells in Cats. J Vet Intern Med. 2016;30:157-63 pubmed publisher
Umezaki Y, Hashimoto Y, Nishishita N, Kawamata S, Baba S. Human Gingival Integration-Free iPSCs; a Source for MSC-Like Cells. Int J Mol Sci. 2015;16:13633-48 pubmed publisher
Nemeth K, Wilson T, Ren J, Sabatino M, Stroncek D, Krepuska M, et al. Impaired function of bone marrow stromal cells in systemic mastocytosis. Stem Cell Res. 2015;15:42-53 pubmed publisher
Zhou F, Gao S, Wang L, Sun C, Chen L, Yuan P, et al. Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model. Stem Cell Res Ther. 2015;6:92 pubmed publisher
Lee D, Su J, Kim H, Chang B, Papatsenko D, Zhao R, et al. Modeling familial cancer with induced pluripotent stem cells. Cell. 2015;161:240-54 pubmed publisher
Feng Y, Zhu M, Dangelmajer S, Lee Y, Wijesekera O, Castellanos C, et al. Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility, and tropism to brain cancer. Cell Death Dis. 2014;5:e1567 pubmed publisher
Shen K, Luk S, Hicks D, Elman J, Bohr S, Iwamoto Y, et al. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014;5:5662 pubmed publisher
Wheway J, Latham S, Combes V, Grau G. Endothelial microparticles interact with and support the proliferation of T cells. J Immunol. 2014;193:3378-87 pubmed publisher
Masuda H, Tanaka R, Fujimura S, Ishikawa M, Akimaru H, Shizuno T, et al. Vasculogenic conditioning of peripheral blood mononuclear cells promotes endothelial progenitor cell expansion and phenotype transition of anti-inflammatory macrophage and T lymphocyte to cells with regenerative potential. J Am Heart Assoc. 2014;3:e000743 pubmed publisher
Ahmed N, Iu J, Brown C, Taylor D, Kandel R. Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction. Tissue Eng Part A. 2014;20:2224-33 pubmed publisher
Mendez J, Ghaedi M, Steinbacher D, Niklason L. Epithelial cell differentiation of human mesenchymal stromal cells in decellularized lung scaffolds. Tissue Eng Part A. 2014;20:1735-46 pubmed publisher
Guijarro Muñoz I, Compte M, Álvarez Cienfuegos A, Alvarez Vallina L, Sanz L. Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-?B signaling pathway and proinflammatory response in human pericytes. J Biol Chem. 2014;289:2457-68 pubmed publisher
Nolan Stevaux O, Zhong W, Culp S, Shaffer K, Hoover J, Wickramasinghe D, et al. Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies. PLoS ONE. 2012;7:e50920 pubmed publisher
Carvalho P, Gimble J, Dias I, Gomes M, Reis R. Xenofree enzymatic products for the isolation of human adipose-derived stromal/stem cells. Tissue Eng Part C Methods. 2013;19:473-8 pubmed publisher
Payne N, Dantanarayana A, Sun G, Moussa L, Caine S, McDonald C, et al. Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in experimental autoimmune demyelination. Cell Adh Migr. 2012;6:179-89 pubmed publisher
Frei C, Opitz I, Soltermann A, Fischer B, Moura U, Rehrauer H, et al. Pleural mesothelioma side populations have a precursor phenotype. Carcinogenesis. 2011;32:1324-32 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD105 (Endoglin) Monoclonal Antibody (SN6), Functional Grade, eBioscience
Catalog # :
16-1057-82
Quantity :
100 µg
Price :
US 284
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Functional Assay: Assay-Dependent
Species :
Human
Clone :
SN6
Isotype :
IgG1, kappa
Storage :
4° C
Description :
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Format :
Liquid
Applications w/Dilutions :
Functional Assay: Assay-Dependent
Aliases :
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA