CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Functional Grade, eBioscience | Invitrogen 16-0719-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Functional Grade, eBioscience

catalog :

16-0719-81

quantity :

50 µg

price :

US 125

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OKT9 (OKT-9)

reactivity :

human, dogs

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 28

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 6d, 6e	Chen J, Cao X, Li B, Zhao Z, Chen S, Lai S, et al. Warburg Effect Is a Cancer Immune Evasion Mechanism Against Macrophage Immunosurveillance. Front Immunol. 2020;11:621757 pubmed publisher
flow cytometry; human; loading ...; fig s11d	Canver M, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern E, et al. Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. Nat Genet. 2017;49:625-634 pubmed publisher
flow cytometry; human; loading ...; fig 9h	Goodier M, Rodríguez Galán A, Lusa C, Nielsen C, Darboe A, Moldoveanu A, et al. Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection. J Immunol. 2016;197:313-25 pubmed publisher
flow cytometry; human; fig 1e	Jobin C, Cloutier M, Simard C, NÃ©ron S. Heterogeneity of in vitro-cultured CD34+ cells isolated from peripheral blood. Cytotherapy. 2015;17:1472-84 pubmed publisher
western blot; human	Fromm J, Tagliente D, Shaver A, Neppalli V, Craig F. Case study interpretation: Report from the ICCS Annual Meeting, Seattle, 2014. Cytometry B Clin Cytom. 2015;88:413-24 pubmed publisher
flow cytometry; human	Badarau A, Rouha H, Malafa S, Logan D, HÃ¥kansson M, Stulik L, et al. Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH. J Biol Chem. 2015;290:142-56 pubmed publisher
immunocytochemistry; dogs; fig 3A	Fields I, Shteyn E, Pypaert M, Proux Gillardeaux V, Kang R, Galli T, et al. v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells. J Cell Biol. 2007;177:477-88 pubmed
	Nandakumar S, McFarland S, Mateyka L, Lareau C, Ulirsch J, Ludwig L, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. elife. 2019;8: pubmed publisher
	Dimitrov V, Bouttier M, Boukhaled G, Salehi Tabar R, Avramescu R, Memari B, et al. Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice. J Biol Chem. 2017;292:20657-20668 pubmed publisher
	Huang N, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun. 2017;8:423 pubmed publisher
	Kim A, Ulirsch J, Wilmes S, Unal E, Moraga I, Karakukcu M, et al. Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 2017;168:1053-1064.e15 pubmed publisher
	Yang C, Ma R, Axton R, Jackson M, Taylor A, Fidanza A, et al. Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells. Stem Cells. 2017;35:886-897 pubmed publisher
	Jackson M, Ma R, Taylor A, Axton R, Easterbrook J, Kydonaki M, et al. Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells. Stem Cells Transl Med. 2016;5:981-90 pubmed publisher
	Giani F, Fiorini C, Wakabayashi A, Ludwig L, Salem R, Jobaliya C, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. 2016;18:73-78 pubmed publisher
	Aparicio Prat E, Arnan C, Sala I, Bosch N, GuigÃ³ R, Johnson R. DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. BMC Genomics. 2015;16:846 pubmed publisher
	Lee H, Gao X, Barrasa M, Li H, Elmes R, Peters L, et al. PPAR-Î± and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 2015;522:474-7 pubmed publisher
	HÃ¤nggi P, Telezhkin V, Kemp P, Schmugge M, Gassmann M, Goede J, et al. Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. Am J Physiol Cell Physiol. 2015;308:C993-C1007 pubmed publisher
	Ma Y, Wang B, Jiang F, Wang D, Liu H, Yan Y, et al. A feedback loop consisting of microRNA 23a/27a and the ?-like globin suppressors KLF3 and SP1 regulates globin gene expression. Mol Cell Biol. 2013;33:3994-4007 pubmed publisher
	Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
	Sasaki H, Toda T, Furukawa T, Mawatari Y, Takaesu R, Shimizu M, et al. ?-1,6-Fucosyltransferase (FUT8) inhibits hemoglobin production during differentiation of murine and K562 human erythroleukemia cells. J Biol Chem. 2013;288:16839-47 pubmed publisher
	Zhang X, Cruz F, Terry M, Remotti F, Matushansky I. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene. 2013;32:2249-60, 2260.e1-21 pubmed publisher
	Woo A, Kim J, Xu J, Huang H, Cantor A. Role of ZBP-89 in human globin gene regulation and erythroid differentiation. Blood. 2011;118:3684-93 pubmed publisher
	Alvares C, Schenk T, Hulkki S, Min T, Vijayaraghavan G, Yeung J, et al. Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations. Br J Haematol. 2011;154:457-65 pubmed publisher
	Adams W, Gujer C, McInerney G, Gall J, Petrovas C, Karlsson Hedestam G, et al. Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation. Proc Natl Acad Sci U S A. 2011;108:7499-504 pubmed publisher
	Muranyi A, Dedhar S, Hogge D. Targeting integrin linked kinase and FMS-like tyrosine kinase-3 is cytotoxic to acute myeloid leukemia stem cells but spares normal progenitors. Leuk Res. 2010;34:1358-65 pubmed publisher
	Fukuchi K, Steiniger S, Deryugina E, Liu Y, Lowery C, Gloeckner C, et al. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Mol Pharm. 2010;7:245-53 pubmed publisher
	Terng H, Gessner R, Fuchs H, Stahl U, Lang C. Human transferrin receptor is active and plasma membrane-targeted in yeast. FEMS Microbiol Lett. 1998;160:61-7 pubmed
	Franco A, Paroli M, Testa U, Benvenuto R, Peschle C, Balsano F, et al. Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes. J Exp Med. 1992;175:1195-205 pubmed

product information

Product Type :

Antibody

Product Name :

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Functional Grade, eBioscience

Catalog # :

16-0719-81

Quantity :

50 µg

Price :

US 125

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Control: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Species :

Human

Clone :

OKT9 (OKT-9)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

more info or order :

Invitrogen product webpage