CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Functional Grade, eBioscience™ | Invitrogen 16-0719-38 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Functional Grade, eBioscience™

catalog :

16-0719-38

quantity :

5 mg

price :

US 2500

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OKT9 (OKT-9)

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Reference
Huang N, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun. 2017;8:423 pubmed publisher
Jackson M, Ma R, Taylor A, Axton R, Easterbrook J, Kydonaki M, et al. Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells. Stem Cells Transl Med. 2016;5:981-90 pubmed publisher
Giani F, Fiorini C, Wakabayashi A, Ludwig L, Salem R, Jobaliya C, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. 2016;18:73-78 pubmed publisher
Aparicio Prat E, Arnan C, Sala I, Bosch N, GuigÃ³ R, Johnson R. DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. BMC Genomics. 2015;16:846 pubmed publisher
Lee H, Gao X, Barrasa M, Li H, Elmes R, Peters L, et al. PPAR-Î± and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 2015;522:474-7 pubmed publisher
HÃ¤nggi P, Telezhkin V, Kemp P, Schmugge M, Gassmann M, Goede J, et al. Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. Am J Physiol Cell Physiol. 2015;308:C993-C1007 pubmed publisher
Ma Y, Wang B, Jiang F, Wang D, Liu H, Yan Y, et al. A feedback loop consisting of microRNA 23a/27a and the ?-like globin suppressors KLF3 and SP1 regulates globin gene expression. Mol Cell Biol. 2013;33:3994-4007 pubmed publisher
Sasaki H, Toda T, Furukawa T, Mawatari Y, Takaesu R, Shimizu M, et al. ?-1,6-Fucosyltransferase (FUT8) inhibits hemoglobin production during differentiation of murine and K562 human erythroleukemia cells. J Biol Chem. 2013;288:16839-47 pubmed publisher
Zhang X, Cruz F, Terry M, Remotti F, Matushansky I. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene. 2013;32:2249-60, 2260.e1-21 pubmed publisher
Woo A, Kim J, Xu J, Huang H, Cantor A. Role of ZBP-89 in human globin gene regulation and erythroid differentiation. Blood. 2011;118:3684-93 pubmed publisher
Adams W, Gujer C, McInerney G, Gall J, Petrovas C, Karlsson Hedestam G, et al. Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation. Proc Natl Acad Sci U S A. 2011;108:7499-504 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Functional Grade, eBioscience™

Catalog # :

16-0719-38

Quantity :

5 mg

Price :

US 2500

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Control: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Species :

Human

Clone :

OKT9 (OKT-9)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; TFR1; Tfrc; TR; transferrin receptor; transferrin receptor (p90, CD71); Transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

more info or order :

Invitrogen product webpage