CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), Functional Grade, eBioscience™ | Invitrogen 16-0629-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), Functional Grade, eBioscience™

catalog :

16-0629-025

quantity :

25 mg

price :

US 7500.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DREG-56 (DREG56)

reactivity :

human

application :

neutralization, flow cytometry

citations: 13

Reference
Yang C, Siebert J, Burns R, Gerbec Z, Bonacci B, Rymaszewski A, et al. Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome. Nat Commun. 2019;10:3931 pubmed publisher
Wu B, Wang L, Jiang L, Dong L, Xu F, Lu Y, et al. n-butanol extract from Folium isatidis inhibits the lipopolysaccharide-induced downregulation of CXCR1 and CXCR2 on human neutrophils. Mol Med Rep. 2017;: pubmed publisher
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, et al. Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans. J Clin Invest. 2017;127:169-182 pubmed publisher
Abrahimi P, Qin L, Chang W, Bothwell A, Tellides G, Saltzman W, et al. Blocking MHC class II on human endothelium mitigates acute rejection. JCI Insight. 2016;1: pubmed
Till S, Raynsford E, Reynolds C, Quigley K, Grzybowska Kowalczyk A, Saggar L, et al. Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation. Thorax. 2014;69:335-45 pubmed publisher
Stemberger C, Dreher S, Tschulik C, Piossek C, Bet J, Yamamoto T, et al. Novel serial positive enrichment technology enables clinical multiparameter cell sorting. PLoS ONE. 2012;7:e35798 pubmed publisher
Norling L, Dalli J, Flower R, Serhan C, Perretti M. Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol. 2012;32:1970-8 pubmed publisher
Gaborski T, Sealander M, Ehrenberg M, Waugh R, McGrath J. Image correlation microscopy for uniform illumination. J Microsc. 2010;237:39-50 pubmed publisher
Ingersoll M, Spanbroek R, Lottaz C, Gautier E, Frankenberger M, Hoffmann R, et al. Comparison of gene expression profiles between human and mouse monocyte subsets. Blood. 2010;115:e10-9 pubmed publisher
Gaborski T, Clark A, Waugh R, McGrath J. Membrane mobility of beta2 integrins and rolling associated adhesion molecules in resting neutrophils. Biophys J. 2008;95:4934-47 pubmed publisher
Huarte E, Cubillos Ruiz J, Nesbeth Y, Scarlett U, Martinez D, Engle X, et al. PILAR is a novel modulator of human T-cell expansion. Blood. 2008;112:1259-68 pubmed publisher
Chen W, Evans E, McEver R, Zhu C. Monitoring receptor-ligand interactions between surfaces by thermal fluctuations. Biophys J. 2008;94:694-701 pubmed
Humblet Baron S, Sather B, Anover S, Becker Herman S, Kasprowicz D, Khim S, et al. Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis. J Clin Invest. 2007;117:407-18 pubmed

product information

Product Type :

Antibody

Product Name :

CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), Functional Grade, eBioscience™

Catalog # :

16-0629-025

Quantity :

25 mg

Price :

US 7500.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent

Species :

Human

Clone :

DREG-56 (DREG56)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

A.11; AI528707; CD62 antigen-like family member L; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LECAM1; LECAM-1; LEU8; Leu-8; Leukocyte adhesion molecule 1; leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lnhr; LSEL; L-selectin; Ly22; Ly-22; Lyam1; Lyam-1; Ly-m22; Lymph node homing receptor; lymphocyte adhesion molecule 1; lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; pln homing receptor; PLNHR; SELE; selectin E (endothelial adhesion molecule 1); selectin L; selectin L (lymphocyte adhesion molecule 1); selectin, lymphocyte; Sell; TQ1