CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), Functional Grade, eBioscience™ | Invitrogen 16-0519-38 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), Functional Grade, eBioscience™

catalog :

16-0519-38

quantity :

5 mg

price :

US 2500

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

23C6

reactivity :

human

application :

immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

citations: 2

Reference
Chen W, Cao Z, Sugaya S, Lopez M, Sendra V, Laver N, et al. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nat Commun. 2016;7:11302 pubmed publisher
Lescarbeau R, Seib F, Prewitz M, Werner C, Kaplan D. In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors. PLoS ONE. 2012;7:e40372 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), Functional Grade, eBioscience™

Catalog # :

16-0519-38

Quantity :

5 mg

Price :

US 2500

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Neutralization: Assay-Dependent

Species :

Human

Clone :

23C6

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Neutralization: Assay-Dependent

Aliases :

antigen CD61; antigen identified by monoclonal antibody L230; BDPLT16; BDPLT2; CD51; CD61; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; GT; integrin; integrin alpha V; integrin alpha-5 beta-3; Integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin beta 3; integrin beta 3 (Cd61); Integrin beta-3; integrin subunit alpha V; integrin subunit beta 3; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGAV; Itgb3; MSK8; Platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha subunit; Vitronectin receptor subunit alpha; VNRA; VTNR