product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD24 Monoclonal Antibody (M1/69), Functional Grade, eBioscience™
catalog :
16-0242-85
quantity :
500 µg
price :
US 358
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M1/69
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 73
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:250; loading ...
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Datta M, Staszewski O. Hdac1 and Hdac2 are essential for physiological maturation of a Cx3cr1 expressing subset of T-lymphocytes. BMC Res Notes. 2021;14:135 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Steer C, Mathä L, Shim H, Takei F. Lung group 2 innate lymphoid cells are trained by endogenous IL-33 in the neonatal period. JCI Insight. 2020;5: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Zhou S, Wu W, Wang Z, Wang Z, Su Q, Li X, et al. RelB regulates the homeostatic proliferation but not the function of Tregs. BMC Immunol. 2020;21:37 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig 3s1d
Stebegg M, Bignon A, Hill D, Silva Cayetano A, Krueger C, Vanderleyden I, et al. Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Joshi N, Watanabe S, Verma R, Jablonski R, Chen C, Cheresh P, et al. A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages. Eur Respir J. 2020;55: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 8e
He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, et al. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018;9:4870 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; fig s2
Zhao D, Kim Y, Jeong S, Greenson J, Chaudhry M, Hoepting M, et al. Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease. J Clin Invest. 2018;128:4970-4979 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Xing S, Shao P, Li F, Zhao X, Seo W, Wheat J, et al. Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity. J Exp Med. 2018;215:2211-2226 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3d
Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5c
Bröker K, Figge J, Magnusen A, Manz R, Köhl J, Karsten C. A Novel Role for C5a in B-1 Cell Homeostasis. Front Immunol. 2018;9:258 pubmed publisher
  • flow cytometry; mouse; fig 1c
Anderson D, Grajales Reyes G, Satpathy A, Vasquez Hueichucura C, Murphy T, Murphy K. Revisiting the specificity of the MHC class?II transactivator CIITA in classical murine dendritic cells in vivo. Eur J Immunol. 2017;47:1317-1323 pubmed publisher
  • flow cytometry; mouse; 1:200; fig 6
Swamy M, Pathak S, Grzes K, Damerow S, Sinclair L, van Aalten D, et al. Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. Nat Immunol. 2016;17:712-20 pubmed publisher
  • flow cytometry; mouse; fig 2
Kaplan J, Marshall M, C McSkimming C, Harmon D, Garmey J, Oldham S, et al. Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue. Mol Metab. 2015;4:779-94 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Van Helden M, Goossens S, Daussy C, Mathieu A, Faure F, Marçais A, et al. Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection. J Exp Med. 2015;212:2015-25 pubmed publisher
  • flow cytometry; mouse; fig 2
Richardson G, Lannigan J, Macara I. Does FACS perturb gene expression?. Cytometry A. 2015;87:166-75 pubmed publisher
  • flow cytometry; mouse; fig 4
Guo X, Tanaka Y, Kondo M. Thymic precursors of TCRαβ(+)CD8αα(+) intraepithelial lymphocytes are negative for CD103. Immunol Lett. 2015;163:40-8 pubmed publisher
  • flow cytometry; mouse; fig 1
  • immunohistochemistry; human; fig 2
Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh A, et al. p53? is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proc Natl Acad Sci U S A. 2014;111:E3287-96 pubmed publisher
  • flow cytometry; mouse; fig s8a
Redecke V, Wu R, Zhou J, Finkelstein D, Chaturvedi V, High A, et al. Hematopoietic progenitor cell lines with myeloid and lymphoid potential. Nat Methods. 2013;10:795-803 pubmed publisher
  • flow cytometry; mouse
Mathew R, Seiler M, Scanlon S, Mao A, Constantinides M, Bertozzi Villa C, et al. BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature. 2012;491:618-21 pubmed publisher
  • flow cytometry; mouse; fig 1
Sadri N, Lu J, Badura M, Schneider R. AUF1 is involved in splenic follicular B cell maintenance. BMC Immunol. 2010;11:1 pubmed publisher
  • flow cytometry; mouse
Hale J, Boursalian T, Turk G, Fink P. Thymic output in aged mice. Proc Natl Acad Sci U S A. 2006;103:8447-52 pubmed
Chiang H, Lu H, Sudhakar J, Chen Y, Shih N, Weng Y, et al. IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence. Nat Commun. 2022;13:874 pubmed publisher
Habowski A, Flesher J, Bates J, Tsai C, Martin K, Zhao R, et al. Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt. Commun Biol. 2020;3:453 pubmed publisher
Gagniac L, Rusidzé M, Boudou F, Cagnet S, Adlanmerini M, Jeannot P, et al. Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium. Development. 2020;147: pubmed publisher
Hillyer L, Kang J, Ma D. Lifelong n-3 Polyunsaturated Fatty Acid Exposure Modulates Size of Mammary Epithelial Cell Populations and Expression of Caveolae Resident Proteins in Fat-1 Mice. Nutrients. 2019;11: pubmed publisher
Bagadia P, Huang X, Liu T, Durai V, Grajales Reyes G, Nitschké M, et al. An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. Nat Immunol. 2019;20:1174-1185 pubmed publisher
Glal D, Sudhakar J, Lu H, Liu M, Chiang H, Liu Y, et al. ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. Front Immunol. 2018;9:2522 pubmed publisher
Hrckulak D, Janeckova L, Lanikova L, Kriz V, Horazna M, Babosova O, et al. Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells. Genes (Basel). 2018;9: pubmed publisher
Zwick R, Rudolph M, Shook B, Holtrup B, Roth E, Lei V, et al. Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation. Nat Commun. 2018;9:3592 pubmed publisher
Robles Valero J, Lorenzo Martín L, Menacho Márquez M, Fernández Pisonero I, Abad A, Camos M, et al. A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2017;32:608-623.e9 pubmed publisher
Ayre D, Chute I, Joy A, Barnett D, Hogan A, Grüll M, et al. CD24 induces changes to the surface receptors of B cell microvesicles with variable effects on their RNA and protein cargo. Sci Rep. 2017;7:8642 pubmed publisher
Belogortseva N, Krezalek M, Guyton K, Labno C, Poroyko V, Zaborina O, et al. Media from macrophages co-incubated with Enterococcus faecalis induces epithelial cell monolayer reassembly and altered cell morphology. PLoS ONE. 2017;12:e0182825 pubmed publisher
Stengel K, Barnett K, Wang J, Liu Q, Hodges E, Hiebert S, et al. Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development. Proc Natl Acad Sci U S A. 2017;114:8608-8613 pubmed publisher
Havas K, Milchevskaya V, Radic K, Alladin A, Kafkia E, Garcia M, et al. Metabolic shifts in residual breast cancer drive tumor recurrence. J Clin Invest. 2017;127:2091-2105 pubmed publisher
Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher
Briseño C, Gargaro M, Durai V, Davidson J, Theisen D, Anderson D, et al. Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms. Proc Natl Acad Sci U S A. 2017;114:3957-3962 pubmed publisher
Ambrosi T, Scialdone A, Graja A, Gohlke S, Jank A, Bocian C, et al. Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration. Cell Stem Cell. 2017;20:771-784.e6 pubmed publisher
van Nieuwenhuijze A, Dooley J, Humblet Baron S, Sreenivasan J, Koenders M, Schlenner S, et al. Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice. Cell Mol Life Sci. 2017;74:2095-2106 pubmed publisher
Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher
Connor L, Tang S, Cognard E, Ochiai S, Hilligan K, Old S, et al. Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles. J Exp Med. 2017;214:125-142 pubmed publisher
Forster M, Farrington K, Petrov J, Belle J, Mindt B, Witalis M, et al. MYSM1-dependent checkpoints in B cell lineage differentiation and B cell-mediated immune response. J Leukoc Biol. 2017;101:643-654 pubmed publisher
Wilson G, Hewit K, Pallas K, Cairney C, Lee K, Hansell C, et al. Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland. Development. 2017;144:74-82 pubmed publisher
Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed publisher
Kugler D, Flomerfelt F, Costa D, Laky K, Kamenyeva O, Mittelstadt P, et al. Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes. J Exp Med. 2016;213:3041-3056 pubmed
Wu X, Briseño C, Durai V, Albring J, Haldar M, Bagadia P, et al. Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells. J Exp Med. 2016;213:2553-2565 pubmed
Rivera Gonzalez G, Shook B, Andrae J, Holtrup B, Bollag K, Betsholtz C, et al. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis. Cell Stem Cell. 2016;19:738-751 pubmed publisher
Alves da Costa T, Di Gangi R, Thomé R, Barreto Felisbino M, Pires Bonfanti A, Lumi Watanabe Ishikawa L, et al. Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis. PLoS ONE. 2016;11:e0164745 pubmed publisher
Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
Drennan M, Govindarajan S, Verheugen E, Coquet J, Staal J, McGuire C, et al. NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20. J Exp Med. 2016;213:1973-81 pubmed publisher
Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, et al. Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator. J Exp Med. 2016;213:1441-58 pubmed publisher
Monteiro M, Agua Doce A, Almeida C, Fonseca Pereira D, Veiga Fernandes H, Graca L. IL-9 Expression by Invariant NKT Cells Is Not Imprinted during Thymic Development. J Immunol. 2015;195:3463-71 pubmed publisher
Ayre D, Elstner M, Smith N, Moores E, Hogan A, Christian S. Dynamic regulation of CD24 expression and release of CD24-containing microvesicles in immature B cells in response to CD24 engagement. Immunology. 2015;146:217-33 pubmed publisher
Kishimoto M, Matsuda T, Yanase S, Katsumi A, Suzuki N, Ikejiri M, et al. Rhof promotes murine marginal zone B cell development. Nagoya J Med Sci. 2014;76:293-305 pubmed
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher
Matsuda T, Yanase S, Takaoka A, Maruyama M. The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. Immun Ageing. 2015;12:1 pubmed publisher
Khaled W, Choon Lee S, Stingl J, Chen X, Raza Ali H, Rueda O, et al. BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells. Nat Commun. 2015;6:5987 pubmed publisher
Shahi P, Slorach E, Wang C, Chou J, Lu A, Ruderisch A, et al. The Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion. J Biol Chem. 2015;290:3803-13 pubmed publisher
Habbeddine M, Verbeke P, Karaz S, Bobé P, Kanellopoulos Langevin C. Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface. PLoS ONE. 2014;9:e107267 pubmed publisher
Prater M, Petit V, Alasdair Russell I, Giraddi R, Shehata M, Menon S, et al. Mammary stem cells have myoepithelial cell properties. Nat Cell Biol. 2014;16:942-50, 1-7 pubmed publisher
Zhang X, Martinez D, Koledova Z, Qiao G, Streuli C, Lu P. FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis. Development. 2014;141:3352-62 pubmed publisher
Mich J, Signer R, Nakada D, Pineda A, Burgess R, Vue T, et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. elife. 2014;3:e02669 pubmed publisher
Kaanta A, Virtanen C, Selfors L, Brugge J, Neel B. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Res. 2013;15:R65 pubmed
Mead A, Kharazi S, Atkinson D, Macaulay I, Pecquet C, Loughran S, et al. FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors. Cell Rep. 2013;3:1766-76 pubmed publisher
Wang F, Scoville D, He X, Mahé M, Box A, Perry J, et al. Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay. Gastroenterology. 2013;145:383-95.e1-21 pubmed publisher
Berry R, Rodeheffer M. Characterization of the adipocyte cellular lineage in vivo. Nat Cell Biol. 2013;15:302-8 pubmed publisher
Chou J, Lin J, Brenot A, Kim J, Provot S, Werb Z. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol. 2013;15:201-13 pubmed publisher
Jia Y, Sakabe I, Matsuda T, Hayakawa T, Maruyama M. Restricted expression of new guanine nucleotide exchange factor Zizimin2 in aged acquired immune system. Nagoya J Med Sci. 2012;74:303-11 pubmed
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product information
Product Type :
Antibody
Product Name :
CD24 Monoclonal Antibody (M1/69), Functional Grade, eBioscience™
Catalog # :
16-0242-85
Quantity :
500 µg
Price :
US 358
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 µg/test, Functional assay: Assay-Dependent
Species :
Mouse
Clone :
M1/69
Isotype :
IgG2b, kappa
Storage :
4° C
Description :
CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test, Functional assay: Assay-Dependent
Aliases :
Cd24; CD24 antigen; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 molecule; Cd24a; CD24a antigen; cluster of differentiation 24; FLJ22950; FLJ43543; heat stable antigen; heat-stable antigen; HSA; Ly-52; Lymphocyte antigen 52; M1/69-J11D heat stable antigen; MGC75043; Nectadrin; nectadrin heat stable antigen; R13-Ag; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; X62 heat stable antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA