Published Application/Species/Sample/Dilution | Reference |
---|
- blocking or activating experiments; human; 0.25 ug/ml; loading ...; fig 5d
| Pinkert J, Boehm H, Trautwein M, Doecke W, Wessel F, Ge Y, et al. T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction. Oncoimmunology. 2022;11:2008110 pubmed publisher
|
- blocking or activating experiments; human; 2 ug/ml; loading ...; fig 4b
| Thakkar D, Paliwal S, Dharmadhikari B, Guan S, Liu L, Kar S, et al. Rationally targeted anti-VISTA antibody that blockades the C-C' loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner. J Immunother Cancer. 2022;10: pubmed publisher
|
- blocking or activating experiments; human; 2 ug/ml; loading ...; fig 4a
| Han L, Hu J, Ma B, Wen D, Zhang T, Lu Z, et al. IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto's thyroiditis. Diagn Pathol. 2019;14:52 pubmed publisher
|
- flow cytometry; human; loading ...; fig 1a
| Banki Z, Krabbendam L, Klaver D, Leng T, Kruis S, Mehta H, et al. Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism. Immunol Cell Biol. 2019;97:538-551 pubmed publisher
|
- flow cytometry; human; loading ...; fig 1b
| Pizzolla A, Nguyen T, Sant S, Jaffar J, Loudovaris T, Mannering S, et al. Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles. J Clin Invest. 2018;128:721-733 pubmed publisher
|
- flow cytometry; human; fig 2c
| Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
|
- blocking or activating experiments; human; 1 ug/ml; loading ...; fig 6d
| Kruglova N, Meshkova T, Kopylov A, Mazurov D, Filatov A. Constitutive and activation-dependent phosphorylation of lymphocyte phosphatase-associated phosphoprotein (LPAP). PLoS ONE. 2017;12:e0182468 pubmed publisher
|
- blocking or activating experiments; human; loading ...; tbl 1
| Zheng C, Zheng L, Yoo J, Guo H, Zhang Y, Guo X, et al. Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing. Cell. 2017;169:1342-1356.e16 pubmed publisher
|
- flow cytometry; human; loading ...; fig 3a
| Szabo P, Goswami A, Mazzuca D, Kim K, O Gorman D, Hess D, et al. Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology. J Immunol. 2017;198:2805-2818 pubmed publisher
|
- flow cytometry; human; loading ...; fig 2a
| Su S, Zou Z, Chen F, Ding N, Du J, Shao J, et al. CRISPR-Cas9-mediated disruption of PD-1 on human T cells for adoptive cellular therapies of EBV positive gastric cancer. Oncoimmunology. 2017;6:e1249558 pubmed publisher
|
- flow cytometry; human; loading ...; fig 1
| Zhen A, Rezek V, Youn C, Lam B, Chang N, Rick J, et al. Targeting type I interferon-mediated activation restores immune function in chronic HIV infection. J Clin Invest. 2017;127:260-268 pubmed publisher
|
- flow cytometry; human; loading ...; fig 2c
| Tomic A, Varanasi P, Golemac M, Malic S, Riese P, Borst E, et al. Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand. PLoS Pathog. 2016;12:e1006015 pubmed publisher
|
- blocking or activating experiments; human; 2.5 ug/ml; loading ...; fig 7d
| Guillou L, Babataheri A, Saitakis M, Bohineust A, Dogniaux S, Hivroz C, et al. T-lymphocyte passive deformation is controlled by unfolding of membrane surface reservoirs. Mol Biol Cell. 2016;27:3574-3582 pubmed
|
- blocking or activating experiments; human; fig 6a
| Pageon S, Nicovich P, Mollazade M, Tabarin T, Gaus K. Clus-DoC: a combined cluster detection and colocalization analysis for single-molecule localization microscopy data. Mol Biol Cell. 2016;27:3627-3636 pubmed
|
- blocking or activating experiments; human; fig 1
| Pageon S, Tabarin T, Yamamoto Y, Ma Y, Nicovich P, Bridgeman J, et al. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proc Natl Acad Sci U S A. 2016;113:E5454-63 pubmed publisher
|
| Sullivan K, Lewis H, Hill A, Pandey A, Jackson L, Cabral J, et al. Trisomy 21 consistently activates the interferon response. elife. 2016;5: pubmed publisher
|
- blocking or activating experiments; human; fig 1
| Hahn S, Neuhoff A, Landsberg J, Schupp J, Eberts D, Leukel P, et al. A key role of GARP in the immune suppressive tumor microenvironment. Oncotarget. 2016;7:42996-43009 pubmed publisher
|
- blocking or activating experiments; human; fig 8
| Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
|
- flow cytometry; human; fig 4
| Su S, Hu B, Shao J, Shen B, Du J, Du Y, et al. CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients. Sci Rep. 2016;6:20070 pubmed publisher
|
- blocking or activating experiments; human; fig 2
| Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
|
- flow cytometry; human; loading ...; fig s1a
| Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher
|
- blocking or activating experiments; human; fig 1
| Silacci M, Lembke W, Woods R, Attinger Toller I, Baenziger Tobler N, Batey S, et al. Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases. MAbs. 2016;8:141-9 pubmed publisher
|
- blocking or activating experiments; human; 1 ug/ml; fig 6c
| Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, et al. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol. 2015;16:1077-84 pubmed publisher
|
- flow cytometry; human; fig 1
| Japp A, Kursunel M, Meier S, Mälzer J, Li X, Rahman N, et al. Dysfunction of PSA-specific CD8+ T cells in prostate cancer patients correlates with CD38 and Tim-3 expression. Cancer Immunol Immunother. 2015;64:1487-94 pubmed publisher
|
- blocking or activating experiments; human; fig s5
| Klammt C, Novotná L, Li D, Wolf M, Blount A, Zhang K, et al. T cell receptor dwell times control the kinase activity of Zap70. Nat Immunol. 2015;16:961-9 pubmed publisher
|
- flow cytometry; human; fig 1b
| Wang Y, Zhong H, Xie X, Chen C, Huang D, Shen L, et al. Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection. Proc Natl Acad Sci U S A. 2015;112:E3883-92 pubmed publisher
|
- flow cytometry; human; fig s3
| Mende N, Kuchen E, Lesche M, Grinenko T, Kokkaliaris K, Hanenberg H, et al. CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo. J Exp Med. 2015;212:1171-83 pubmed publisher
|
- blocking or activating experiments; human; 0.01 ug/ml; fig 1
| Tsai P, Chang Y, Lee Y, Ko Y, Yang Y, Lin C, et al. Differentiation of blood T cells: Reprogramming human induced pluripotent stem cells into neuronal cells. J Chin Med Assoc. 2015;78:353-9 pubmed publisher
|
- blocking or activating experiments; human; 5 ug/ml
| Vassena L, Giuliani E, Koppensteiner H, Bolduan S, Schindler M, Doria M. HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes. J Virol. 2015;89:5687-700 pubmed publisher
|
- blocking or activating experiments; human; fig 3
| Severson J, Serracino H, Mateescu V, Raeburn C, McIntyre R, Sams S, et al. PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer. Cancer Immunol Res. 2015;3:620-30 pubmed publisher
|
- blocking or activating experiments; human; 0.5 ug/ml
| Chauhan A, Chen C, Moore T, DiPaolo R. Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset. J Biol Chem. 2015;290:5127-40 pubmed publisher
|
- blocking or activating experiments; human
| Caramalho I, Nunes Silva V, Pires A, Mota C, Pinto A, Nunes Cabaço H, et al. Human regulatory T-cell development is dictated by Interleukin-2 and -15 expressed in a non-overlapping pattern in the thymus. J Autoimmun. 2015;56:98-110 pubmed publisher
|
| Lim D, Yawata N, Selva K, Li N, Tsai C, Yeong L, et al. The combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus. J Immunol. 2014;193:5065-75 pubmed publisher
|
- blocking or activating experiments; human; 2 ug/ml
| O Regan N, Steinfelder S, Venugopal G, Rao G, Lucius R, Srikantam A, et al. Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses. PLoS Negl Trop Dis. 2014;8:e3206 pubmed publisher
|
- flow cytometry; human; 0.05 ug/ml
| Ramirez L, Arango T, Thompson E, Naji M, Tebas P, Boyer J. High IP-10 levels decrease T cell function in HIV-1-infected individuals on ART. J Leukoc Biol. 2014;96:1055-63 pubmed publisher
|
- blocking or activating experiments; human
| Kreiser S, Eckhardt J, Kuhnt C, Stein M, Krzyzak L, Seitz C, et al. Murine CD83-positive T cells mediate suppressor functions in vitro and in vivo. Immunobiology. 2015;220:270-9 pubmed publisher
|
| Tarbox J, Keppel M, Topcagic N, Mackin C, Ben Abdallah M, Baszis K, et al. Elevated double negative T cells in pediatric autoimmunity. J Clin Immunol. 2014;34:594-9 pubmed publisher
|
| Mao C, Mou X, Zhou Y, Yuan G, Xu C, Liu H, et al. Tumor-activated TCR??? T cells from gastric cancer patients induce the antitumor immune response of TCR??? T cells via their antigen-presenting cell-like effects. J Immunol Res. 2014;2014:593562 pubmed publisher
|
- blocking or activating experiments; human; 3 ug/ml
| Yang C, Li J, Chiu L, Lan J, Chen D, Chuang H, et al. Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation. J Immunol. 2014;192:1547-57 pubmed publisher
|
- blocking or activating experiments; human
| Zouk H, d Hennezel E, Du X, Ounissi Benkalha H, Piccirillo C, Polychronakos C. Functional evaluation of the role of C-type lectin domain family 16A at the chromosome 16p13 locus. Clin Exp Immunol. 2014;175:485-97 pubmed publisher
|
- blocking or activating experiments; human; 2.5 ug/ml
| Magrini E, Szabo I, Doni A, Cibella J, Viola A. Serotonin-mediated tuning of human helper T cell responsiveness to the chemokine CXCL12. PLoS ONE. 2011;6:e22482 pubmed publisher
|
- flow cytometry; human; fig 2
| Correia M, Costa A, Uhrberg M, Cardoso E, Arosa F. IL-15 induces CD8+ T cells to acquire functional NK receptors capable of modulating cytotoxicity and cytokine secretion. Immunobiology. 2011;216:604-12 pubmed publisher
|
- flow cytometry; human; fig 4
- flow cytometry; rhesus macaque; fig 4
| Richardson M, Carroll R, Stremlau M, Korokhov N, Humeau L, Silvestri G, et al. Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha. J Virol. 2008;82:11117-28 pubmed publisher
|
- blocking or activating experiments; human
| Kueng H, Leb V, Haiderer D, Raposo G, Thery C, Derdak S, et al. General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol. 2007;81:8666-76 pubmed
|
- blocking or activating experiments; human; 0.5 ug/ml
| Clarke S, Betts G, Plant A, Wright K, El Shanawany T, Harrop R, et al. CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. PLoS ONE. 2006;1:e129 pubmed
|
- blocking or activating experiments; human
| Hoves S, Krause S, Schutz C, Halbritter D, Scholmerich J, Herfarth H, et al. Monocyte-derived human macrophages mediate anergy in allogeneic T cells and induce regulatory T cells. J Immunol. 2006;177:2691-8 pubmed
|
| Quiroga M, Pasquinelli V, Martinez G, Jurado J, Zorrilla L, Musella R, et al. Inducible costimulator: a modulator of IFN-gamma production in human tuberculosis. J Immunol. 2006;176:5965-74 pubmed
|
| Lin M, Bhakdi S, Tan D, Lee J, Tai D, Pavesi A, et al. Lytic efficiency of immunosuppressive drug-resistant armoured T cells against circulating HBV-related HCC in whole blood. Immunother Adv. 2023;3:ltad015 pubmed publisher
|
| Jaeger H, Davis D, Nair A, Shrestha P, Stream A, Yaparla A, et al. Mechanism and therapeutic implications of pomalidomide-induced immune surface marker upregulation in EBV-positive lymphomas. Sci Rep. 2023;13:11596 pubmed publisher
|
| Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, et al. HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway. J Exp Clin Cancer Res. 2023;42:38 pubmed publisher
|
| Kong F, Ye Q, Xiong Y. Comprehensive analysis of prognosis and immune function of CD70-CD27 signaling axis in pan-cancer. Funct Integr Genomics. 2023;23:48 pubmed publisher
|
| Rode A, Buus T, Mraz V, Al Jaberi F, Lopez D, Ford S, et al. Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor. Cells. 2022;11: pubmed publisher
|
| Banerjee A, Li D, Guo Y, Mei Z, Lau C, Chen K, et al. A reengineered common chain cytokine augments CD8+ T cell-dependent immunotherapy. JCI Insight. 2022;7: pubmed publisher
|
| Jensen L, Hoh T, Williamson D, Griffi xe9 J, Sage D, Rubin Delanchy P, et al. Correction of multiple-blinking artifacts in photoactivated localization microscopy. Nat Methods. 2022;19:594-602 pubmed publisher
|
| Saveljeva S, Sewell G, Ramshorn K, Cader M, West J, Clare S, et al. A purine metabolic checkpoint that prevents autoimmunity and autoinflammation. Cell Metab. 2022;34:106-124.e10 pubmed publisher
|
| Siegemund M, Oak P, Hansbauer E, Allersdorfer A, Utschick K, Winter A, et al. Pharmacokinetic Engineering of OX40-Blocking Anticalin Proteins Using Monomeric Plasma Half-Life Extension Domains. Front Pharmacol. 2021;12:759337 pubmed publisher
|
| Geuijen C, Tacken P, Wang L, Klooster R, Van Loo P, Zhou J, et al. A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade. Nat Commun. 2021;12:4445 pubmed publisher
|
| Puertas M, Bayón Gil Á, Garcia Guerrero M, Salgado M, Urrea V, Morón López S, et al. VIP-SPOT: an Innovative Assay To Quantify the Productive HIV-1 Reservoir in the Monitoring of Cure Strategies. MBio. 2021;12:e0056021 pubmed publisher
|
| Xun X, Zhang C, Wang S, Hu S, Xiang X, Cheng Q, et al. Cyclooxygenase-2 expressed hepatocellular carcinoma induces cytotoxic T lymphocytes exhaustion through M2 macrophage polarization. Am J Transl Res. 2021;13:4360-4375 pubmed
|
| Szanto C, Cornel A, Tamminga S, Delemarre E, de Koning C, van den Beemt D, et al. Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma. Cancers (Basel). 2021;13: pubmed publisher
|
| Feldman T, Bercovich A, Moskovitz Y, Chapal Ilani N, Mitchell A, Medeiros J, et al. Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining. Nat Commun. 2021;12:2455 pubmed publisher
|
| Rubio Perez C, Planas Rigol E, Trincado J, Bonfill Teixidor E, Arias A, Marchese D, et al. Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment. Nat Commun. 2021;12:1503 pubmed publisher
|
| Zehravi M, Wahid M, Ashraf J. Episomal reprogramming of Duchenne muscular dystrophy patients derived CD3+ T cells towards induced pluripotent stem cells. Pak J Med Sci. 2021;37:432-438 pubmed publisher
|
| Bost P, De Sanctis F, Cane S, Ugel S, Donadello K, Castellucci M, et al. Deciphering the state of immune silence in fatal COVID-19 patients. Nat Commun. 2021;12:1428 pubmed publisher
|
| Li H, Kuang X, Liang L, Ye Y, Zhang Y, Li J, et al. The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1. Adv Sci (Weinh). 2021;8:2001596 pubmed publisher
|
| Liu B, Xie Y, Mei X, Sun Y, Shi W, Wu Z. Reciprocal regulation of interleukin-17A and interleukin-22 secretion through aryl hydrocarbon receptor activation in CD4+ T cells of patients with vitiligo. Exp Ther Med. 2021;21:158 pubmed publisher
|
| Wang T, Zhou Q, Shang Y. Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma. J Innate Immun. 2021;13:38-48 pubmed publisher
|
| Podojil J, Ifergan I, Chiang M, Meeks J, Miller S. Methodology for in vitro Assessment of Human T Cell Activation and Blockade. Bio Protoc. 2020;10:e3644 pubmed publisher
|
| Lund M, Howard C, Thurecht K, Campbell D, Mahler S, Walsh B. A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer. 2020;20:1214 pubmed publisher
|
| Renavikar P, Sinha S, Brate A, Borcherding N, Crawford M, Steward Tharp S, et al. IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation. Front Immunol. 2020;11:568630 pubmed publisher
|
| Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai C, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. 2020;183:1479-1495.e20 pubmed publisher
|
| Ferretti A, Kula T, Wang Y, Nguyen D, Weinheimer A, Dunlap G, et al. Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein. Immunity. 2020;53:1095-1107.e3 pubmed publisher
|
| Yang J, Zhang J, Lu R, Tan Y, Du G, Zhou G. T cell-derived exosomes induced macrophage inflammatory protein-1α/β drive the trafficking of CD8+ T cells in oral lichen planus. J Cell Mol Med. 2020;24:14086-14098 pubmed publisher
|
| Biemann R, Roomp K, Noor F, Krishnan S, Li Z, Shahzad K, et al. Gene expression profile of CD14+ blood monocytes following lifestyle-induced weight loss in individuals with metabolic syndrome. Sci Rep. 2020;10:17855 pubmed publisher
|
| Lee J, Sheen J, Lim O, Lee Y, Ryu J, Shin D, et al. Abrogation of HLA surface expression using CRISPR/Cas9 genome editing: a step toward universal T cell therapy. Sci Rep. 2020;10:17753 pubmed publisher
|
| Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, et al. Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1. Genome Med. 2020;12:83 pubmed publisher
|
| Sadik A, Somarribas Patterson L, Oztürk S, Mohapatra S, Panitz V, Secker P, et al. IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression. Cell. 2020;182:1252-1270.e34 pubmed publisher
|
| Kuehn H, Bernasconi A, Niemela J, Almejún M, Gallego W, Goel S, et al. A Nonsense N -Terminus NFKB2 Mutation Leading to Haploinsufficiency in a Patient with a Predominantly Antibody Deficiency. J Clin Immunol. 2020;40:1093-1101 pubmed publisher
|
| Boshuizen J, Vredevoogd D, Krijgsman O, Ligtenberg M, Blankenstein S, de Bruijn B, et al. Reversal of pre-existing NGFR-driven tumor and immune therapy resistance. Nat Commun. 2020;11:3946 pubmed publisher
|
| Crawford M, Sinha S, Renavikar P, Borcherding N, Karandikar N. CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression. Proc Natl Acad Sci U S A. 2020;117:19408-19414 pubmed publisher
|
| Ferrara M, Chialli G, Ferreira L, Ruggieri E, Careccia G, Preti A, et al. Oxidation of HMGB1 Is a Dynamically Regulated Process in Physiological and Pathological Conditions. Front Immunol. 2020;11:1122 pubmed publisher
|
| Sahin M, Sahin E. Prostaglandin E2 Reverses the Effects of DNA Methyltransferase Inhibitor and TGFB1 on the Conversion of Naive T Cells to iTregs. Transfus Med Hemother. 2020;47:244-253 pubmed publisher
|
| Wragg K, Tan H, Kristensen A, Nguyen Robertson C, Kelleher A, Parsons M, et al. High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile. Cell Rep. 2020;31:107773 pubmed publisher
|
| Rollins M, Spartz E, Stromnes I. T Cell Receptor Engineered Lymphocytes for Cancer Therapy. Curr Protoc Immunol. 2020;129:e97 pubmed publisher
|
| Hu J, Lei B, Wen D, Ma B, Zhang T, Lu Z, et al. IL-2 enhanced MHC class I expression in papillary thyroid cancer with Hashimoto's thyroiditis overcomes immune escape in vitro. J Cancer. 2020;11:4250-4260 pubmed publisher
|
| Lu Z, Hu J, Liu W, Wen D, Wei W, Wang Y, et al. IL-10 Restores MHC Class I Expression and Interferes With Immunity in Papillary Thyroid Cancer With Hashimoto Thyroiditis. Endocrinology. 2020;161: pubmed publisher
|
| Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, et al. JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Cell Death Differ. 2020;: pubmed publisher
|
| Ma Y, Yang Q, Fan M, Zhang L, Gu Y, Jia W, et al. Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation. Cell Prolif. 2020;53:e12802 pubmed publisher
|
| Salazar Y, Zheng X, Brunn D, Raifer H, Picard F, Zhang Y, et al. Microenvironmental Th9- and Th17- lymphocytes induce metastatic spreading in lung cancer. J Clin Invest. 2020;: pubmed publisher
|
| Ko J, Kim H, Jeong H, Lee H, Oh J. Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis. Cell Rep. 2020;30:3806-3820.e6 pubmed publisher
|
| Li W, Aryal M, Shu S, Smithgall T. HIV-1 Nef dimers short-circuit immune receptor signaling by activating Tec-family kinases at the host cell membrane. J Biol Chem. 2020;295:5163-5174 pubmed publisher
|
| Chang Z, Hou A, Chen Y. Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands. Nat Protoc. 2020;15:1507-1524 pubmed publisher
|
| Janssen A, Villacorta Hidalgo J, Beringer D, van Dooremalen S, Fernando F, van Diest E, et al. γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity. Cancer Immunol Res. 2020;8:530-543 pubmed publisher
|
| Kwon M, Kim C, Lee H, Cho H, Kim Y, Lee E, et al. PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors. Clin Cancer Res. 2020;26:1644-1655 pubmed publisher
|
| Wang W, Cohen J, Wallrapp A, Trieu K, Barrios J, Shao F, et al. Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung. Immunity. 2019;51:1102-1118.e7 pubmed publisher
|
| Levring T, Kongsbak Wismann M, Rode A, Al Jaberi F, Lopez D, Met O, et al. Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells. Sci Rep. 2019;9:16725 pubmed publisher
|
| Davies S, Reynolds G, Wilkinson A, Li X, Rose R, Leekha M, et al. Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process. Cell Rep. 2019;29:1610-1620.e4 pubmed publisher
|
| Rossatti P, Ziegler L, Schregle R, Betzler V, Ecker M, Rossy J. Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane. Cells. 2019;8: pubmed publisher
|
| Burchiel S, Lauer F, Factor Litvak P, Liu X, Santella R, Eunus M, et al. An increase in circulating B cells and B cell activation markers in peripheral blood is associated with cigarette smoking in a male cohort in Bangladesh. Toxicol Appl Pharmacol. 2019;384:114783 pubmed publisher
|
| Esfahani K, Al Aubodah T, Thebault P, Lapointe R, Hudson M, Johnson N, et al. Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation. Nat Commun. 2019;10:4712 pubmed publisher
|
| Tanaskovic O, Verga Falzacappa M, Pelicci P. Human cord blood (hCB)-CD34+ humanized mice fail to reject human acute myeloid leukemia cells. PLoS ONE. 2019;14:e0217345 pubmed publisher
|
| Gomez Lopez N, Romero R, Xu Y, Miller D, Arenas Hernandez M, Garcia Flores V, et al. Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth. J Immunol. 2019;203:1793-1807 pubmed publisher
|
| Zhang L, Yu J. Triptolide reverses helper T cell inhibition and down-regulates IFN-γ induced PD-L1 expression in glioma cell lines. J Neurooncol. 2019;143:429-436 pubmed publisher
|
| Oda H, Beck D, Kuehn H, Sampaio Moura N, Hoffmann P, Ibarra M, et al. Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC. Front Immunol. 2019;10:479 pubmed publisher
|
| Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed publisher
|
| Atay C, Kwak T, Lavilla Alonso S, Donthireddy L, Richards A, Moberg V, et al. BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells. Clin Cancer Res. 2019;25:2783-2794 pubmed publisher
|
| Davis D, Shrestha P, Aisabor A, Stream A, Galli V, Pise Masison C, et al. Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells. Oncoimmunology. 2019;8:e1546544 pubmed publisher
|
| Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H. HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. Cell Chem Biol. 2019;26:331-339.e3 pubmed publisher
|
| Tran H, Herz C, Ruf P, Stetter R, Lamy E. Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes. Front Immunol. 2018;9:2949 pubmed publisher
|
| Bamidele A, Svingen P, Sagstetter M, Sarmento O, González M, Braga Neto M, et al. Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. Cell Mol Gastroenterol Hepatol. 2019;7:55-71 pubmed publisher
|
| Li Y, Tan S, Zhang C, Chai Y, He M, Zhang C, et al. Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep. 2018;25:909-920.e4 pubmed publisher
|
| Cao M, Wang C, Chung W, Motabar D, Wang J, Christian E, et al. Characterization and analysis of scFv-IgG bispecific antibody size variants. MAbs. 2018;10:1236-1247 pubmed publisher
|
| Idelson M, Alper R, Obolensky A, Yachimovich Cohen N, Rachmilewitz J, Ejzenberg A, et al. Immunological Properties of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. Stem Cell Reports. 2018;11:681-695 pubmed publisher
|
| Cha J, Yang W, Xia W, Wei Y, Chan L, Lim S, et al. Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Mol Cell. 2018;71:606-620.e7 pubmed publisher
|
| Singh A, Sarangi A, Goel A, Srivastava R, Bhargava R, Gaur P, et al. Effect of administration of a probiotic preparation on gut microbiota and immune response in healthy women in India: an open-label, single-arm pilot study. BMC Gastroenterol. 2018;18:85 pubmed publisher
|
| Boutboul D, Kuehn H, Van de Wyngaert Z, Niemela J, Callebaut I, Stoddard J, et al. Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. J Clin Invest. 2018;128:3071-3087 pubmed publisher
|
| Pan H, Liu J, Deng W, Xing J, Li Q, Wang Z. Site-specific PEGylation of an anti-CEA/CD3 bispecific antibody improves its antitumor efficacy. Int J Nanomedicine. 2018;13:3189-3201 pubmed publisher
|
| Song H, Giorgi E, Ganusov V, Cai F, Athreya G, Yoon H, et al. Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. Nat Commun. 2018;9:1928 pubmed publisher
|
| Provine N, Binder B, FitzPatrick M, Schuch A, Garner L, Williamson K, et al. Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells. Front Immunol. 2018;9:756 pubmed publisher
|
| Compeer E, Kraus F, Ecker M, Redpath G, Amiezer M, Rother N, et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun. 2018;9:1597 pubmed publisher
|
| Shi Y, Zhang P, Wang G, Liu X, Sun X, Zhang X, et al. Description of organ-specific phenotype, and functional characteristics of tissue resident lymphocytes from liver transplantation donor and research on immune tolerance mechanism of liver. Oncotarget. 2018;9:15552-15565 pubmed publisher
|
| Holien T, Gederaas O, Darvekar S, Christensen E, Peng Q. Comparison between 8-methoxypsoralen and 5-aminolevulinic acid in killing T cells of photopheresis patients ex vivo. Lasers Surg Med. 2018;50:469-475 pubmed publisher
|
| Carpier J, Zucchetti A, Bataille L, Dogniaux S, Shafaq Zadah M, Bardin S, et al. Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. J Exp Med. 2018;215:1245-1265 pubmed publisher
|
| Seki A, Rutz S. Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells. J Exp Med. 2018;215:985-997 pubmed publisher
|
| Carisey A, Mace E, Saeed M, Davis D, Orange J. Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells. Curr Biol. 2018;28:489-502.e9 pubmed publisher
|
| Alam M, Gaida M, Debnath S, Tagad H, Miller Jenkins L, Appella E, et al. Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation. PLoS Biol. 2018;16:e2004111 pubmed publisher
|
| Martin S, Wick D, Nielsen J, Little N, Holt R, Nelson B. A library-based screening method identifies neoantigen-reactive T cells in peripheral blood prior to relapse of ovarian cancer. Oncoimmunology. 2017;7:e1371895 pubmed publisher
|
| Sawicka A, Babataheri A, Dogniaux S, Barakat A, González Rodríguez D, Hivroz C, et al. Micropipette force probe to quantify single-cell force generation: application to T-cell activation. Mol Biol Cell. 2017;28:3229-3239 pubmed publisher
|
| Hayashi T, Jean M, Huang H, Simpson S, Santoso N, Zhu J. Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription. Antiviral Res. 2017;146:76-85 pubmed publisher
|
| Tsai A, Khan A, Worgo C, Wang L, Liang Y, Davila E. A Multikinase and DNA-PK Inhibitor Combination Immunomodulates Melanomas, Suppresses Tumor Progression, and Enhances Immunotherapies. Cancer Immunol Res. 2017;5:790-803 pubmed publisher
|
| Kah J, Koh S, Volz T, Ceccarello E, Allweiss L, Lutgehetmann M, et al. Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection. J Clin Invest. 2017;127:3177-3188 pubmed publisher
|
| Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw A, et al. Astrocytic tight junctions control inflammatory CNS lesion pathogenesis. J Clin Invest. 2017;127:3136-3151 pubmed publisher
|
| Bughani U, Saha A, Kuriakose A, Nair R, Sadashivarao R, Venkataraman R, et al. T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab. PLoS ONE. 2017;12:e0180088 pubmed publisher
|
| Li L, Guo X, Shi X, Li C, Wu W, Yan C, et al. Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci U S A. 2017;114:E5891-E5899 pubmed publisher
|
| Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, et al. A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Front Microbiol. 2017;8:1035 pubmed publisher
|
| Saitakis M, Dogniaux S, Goudot C, Bufi N, Asnacios S, Maurin M, et al. Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity. elife. 2017;6: pubmed publisher
|
| Hernández Del Pino R, Pellegrini J, Rovetta A, Peña D, Álvarez G, Rolandelli A, et al. Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses. Immunol Cell Biol. 2017;95:716-728 pubmed publisher
|
| Tello Lafoz M, MartÃnez MartÃnez G, RodrÃguez RodrÃguez C, Albar J, Huse M, Gharbi S, et al. Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse. Traffic. 2017;18:491-504 pubmed publisher
|
| Seignez A, Joly A, Chaumonnot K, Hazoume A, Sanka M, Marcion G, et al. Serum Gp96 is a chaperone of complement-C3 during graft-versus-host disease. JCI Insight. 2017;2:e90531 pubmed publisher
|
| Schober T, Magg T, Laschinger M, Rohlfs M, Linhares N, Puchalka J, et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun. 2017;8:14209 pubmed publisher
|
| Datlinger P, Rendeiro A, Schmidl C, Krausgruber T, Traxler P, Klughammer J, et al. Pooled CRISPR screening with single-cell transcriptome readout. Nat Methods. 2017;14:297-301 pubmed publisher
|
| Chen J, Wang Q, Feng X, Zhang Z, Geng L, Xu T, et al. Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria. Stem Cells Int. 2016;2016:4062789 pubmed publisher
|
| Cárcamo Orive I, Hoffman G, Cundiff P, Beckmann N, D Souza S, Knowles J, et al. Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. Cell Stem Cell. 2017;20:518-532.e9 pubmed publisher
|
| Zhu H, Hu F, Sun X, Zhang X, Zhu L, Liu X, et al. CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus. Front Immunol. 2016;7:512 pubmed
|
| Kiniry B, Ganesh A, Critchfield J, Hunt P, Hecht F, Somsouk M, et al. Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017;10:1008-1020 pubmed publisher
|
| Murugesan S, Hong J, Yi J, Li D, Beach J, Shao L, et al. Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse. J Cell Biol. 2016;215:383-399 pubmed
|
| Puck A, Hopf S, Modak M, Majdic O, Cejka P, Blüml S, et al. The soluble cytoplasmic tail of CD45 (ct-CD45) in human plasma contributes to keep T cells in a quiescent state. Eur J Immunol. 2017;47:193-205 pubmed publisher
|
| Son C, Lee H, Koh E, Shin D, Bae J, Yang K, et al. Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells. Sci Rep. 2016;6:32470 pubmed publisher
|
| Du S, Li Z, Chen C, Tan W, Chi Z, Kwang T, et al. Co-Expansion of Cytokine-Induced Killer Cells and V?9V?2 T Cells for CAR T-Cell Therapy. PLoS ONE. 2016;11:e0161820 pubmed publisher
|
| Starling S, Jolly C. LFA-1 Engagement Triggers T Cell Polarization at the HIV-1 Virological Synapse. J Virol. 2016;90:9841-9854 pubmed publisher
|
| You Y, Tan J, Dai H, Chen H, Xu X, Yang A, et al. MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma. Oncotarget. 2016;7:57099-57116 pubmed publisher
|
| Qualai J, Li L, Cantero J, Tarrats A, Fernández M, Sumoy L, et al. Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. PLoS ONE. 2016;11:e0154253 pubmed publisher
|
| Momose F, Seo N, Akahori Y, Sawada S, Harada N, Ogura T, et al. Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types. PLoS ONE. 2016;11:e0154134 pubmed publisher
|
| Siddiqui I, Erreni M, van Brakel M, Debets R, Allavena P. Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient. J Immunother Cancer. 2016;4:21 pubmed publisher
|
| Jones R, Mueller S, O Connor R, Rimpel K, Sloan D, Karel D, et al. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog. 2016;12:e1005545 pubmed publisher
|
| Pan Y, Wu Y, Ji J, Cai H, Wang H, Jiang Y, et al. Effect of cytokine-induced killer cells on immune function in patients with lung cancer. Oncol Lett. 2016;11:2827-2834 pubmed
|
| Kapoor Kaushik N, Hinde E, Compeer E, Yamamoto Y, Kraus F, Yang Z, et al. Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells. Front Immunol. 2016;7:83 pubmed publisher
|
| Li R, Yan F, Liu L, Li H, Ren B, Hui Z, et al. Cytokine-induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report. Oncol Lett. 2016;11:1885-1888 pubmed
|
| Liu Z, Han H, He X, Li S, Wu C, Yu C, et al. Expression of the galectin-9-Tim-3 pathway in glioma tissues is associated with the clinical manifestations of glioma. Oncol Lett. 2016;11:1829-1834 pubmed
|
| Frasca D, Ferracci F, Diaz A, Romero M, Lechner S, Blomberg B. Obesity decreases B cell responses in young and elderly individuals. Obesity (Silver Spring). 2016;24:615-25 pubmed publisher
|
| Martin M, Leffler J, Smoląg K, Mytych J, Björk A, Chaves L, et al. Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes. Cell Death Differ. 2016;23:903-11 pubmed publisher
|
| Soh K, Tario J, Colligan S, Maguire O, Pan D, Minderman H, et al. Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins. Curr Protoc Cytom. 2016;75:7.45.1-7.45.33 pubmed publisher
|
| Liu C, Jiang J, Gao L, Wang X, Hu X, Wu M, et al. Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways. Arthritis Res Ther. 2015;17:340 pubmed publisher
|
| Ramakrishna V, Sundarapandiyan K, Zhao B, Bylesjo M, Marsh H, Keler T. Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab. J Immunother Cancer. 2015;3:37 pubmed publisher
|
| Kuramitsu S, Ohno M, Ohka F, Shiina S, Yamamichi A, Kato A, et al. Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses. Cancer Gene Ther. 2015;22:487-95 pubmed publisher
|
| Hsu P, Santner Nanan B, Hu M, Skarratt K, Lee C, Stormon M, et al. IL-10 Potentiates Differentiation of Human Induced Regulatory T Cells via STAT3 and Foxo1. J Immunol. 2015;195:3665-74 pubmed publisher
|
| Wienke J, Janssen W, Scholman R, Spits H, van Gijn M, Boes M, et al. A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation. Oncotarget. 2015;6:20037-42 pubmed
|
| Elkord E, Abd Al Samid M, Chaudhary B. Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP. Oncotarget. 2015;6:20026-36 pubmed
|
| Roberts R, Eitas T, Byrne J, Johnson B, Short P, McKinnon K, et al. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials. 2015;72:1-10 pubmed publisher
|
| Mikucki M, Fisher D, Matsuzaki J, Skitzki J, Gaulin N, Muhitch J, et al. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Nat Commun. 2015;6:7458 pubmed publisher
|
| Kim S, Theunissen J, Balibalos J, Liao Chan S, Babcock M, Wong T, et al. A novel antibody-drug conjugate targeting SAIL for the treatment of hematologic malignancies. Blood Cancer J. 2015;5:e316 pubmed publisher
|
| Tan Y, Deng J, Neilson J. RAX2: a genome-wide detection method of condition-associated transcription variation. Nucleic Acids Res. 2015;43:e96 pubmed publisher
|
| Ji Q, Salomon A. Wide-scale quantitative phosphoproteomic analysis reveals that cold treatment of T cells closely mimics soluble antibody stimulation. J Proteome Res. 2015;14:2082-9 pubmed publisher
|
| McCracken M, Vatakis D, Dixit D, McLaughlin J, Zack J, Witte O. Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. J Clin Invest. 2015;125:1815-26 pubmed publisher
|
| Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler F, et al. Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway. elife. 2015;4: pubmed publisher
|
| Schultz H, Nitze L, Zeuthen L, Keller P, Gruhler A, Pass J, et al. Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor. J Immunol. 2015;194:3169-79 pubmed publisher
|
| Cénit M, MartÃnez Florensa M, Consuegra M, Bonet L, Carnero Montoro E, Armiger N, et al. Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients. PLoS ONE. 2014;9:e113090 pubmed publisher
|
| Ji Q, Ding Y, Salomon A. SRC homology 2 domain-containing leukocyte phosphoprotein of 76 kDa (SLP-76) N-terminal tyrosine residues regulate a dynamic signaling equilibrium involving feedback of proximal T-cell receptor (TCR) signaling. Mol Cell Proteomics. 2015;14:30-40 pubmed publisher
|
| Kumaresan P, Manuri P, Albert N, Maiti S, Singh H, Mi T, et al. Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection. Proc Natl Acad Sci U S A. 2014;111:10660-5 pubmed publisher
|
| Quandt D, Jasinski Bergner S, Müller U, Schulze B, Seliger B. Synergistic effects of IL-4 and TNF? on the induction of B7-H1 in renal cell carcinoma cells inhibiting allogeneic T cell proliferation. J Transl Med. 2014;12:151 pubmed publisher
|
| Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, et al. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity. Cell Signal. 2014;26:2016-29 pubmed publisher
|
| Mellergaard M, Skovbakke S, Schneider C, Lauridsen F, Andresen L, Jensen H, et al. N-glycosylation of asparagine 8 regulates surface expression of major histocompatibility complex class I chain-related protein A (MICA) alleles dependent on threonine 24. J Biol Chem. 2014;289:20078-91 pubmed publisher
|
| Kang J, Wang P, Hwang P. Cell-based measurements of mitochondrial function in human subjects. Methods Enzymol. 2014;542:209-21 pubmed publisher
|
| Hartmann N, Giese N, Giese T, Poschke I, Offringa R, Werner J, et al. Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer. Clin Cancer Res. 2014;20:3422-33 pubmed publisher
|
| Wang D, Feng X, Lu L, Konkel J, Zhang H, Chen Z, et al. A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2234-45 pubmed publisher
|
| Guo Y, Riley K, Iwasaki A, Steitz J. Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Mol Cell. 2014;54:67-79 pubmed publisher
|
| Kim P, Jochems C, Grenga I, Donahue R, Tsang K, Gulley J, et al. Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy. J Immunol. 2014;192:2622-33 pubmed publisher
|
| Bashour K, Gondarenko A, Chen H, Shen K, Liu X, Huse M, et al. CD28 and CD3 have complementary roles in T-cell traction forces. Proc Natl Acad Sci U S A. 2014;111:2241-6 pubmed publisher
|
| Yi L, Zhao Y, Wang X, Dai M, Hellstrom K, Hellstrom I, et al. Human and mouse CD137 have predominantly different binding CRDs to their respective ligands. PLoS ONE. 2014;9:e86337 pubmed publisher
|
| Li L, Kim H, Nellore A, Patsoukis N, Petkova V, McDonough S, et al. Prostaglandin E2 promotes survival of naive UCB T cells via the Wnt/?-catenin pathway and alters immune reconstitution after UCBT. Blood Cancer J. 2014;4:e178 pubmed publisher
|
| Jain N, George B, Thanabalu T. Wiskott-Aldrich Syndrome causing mutation, Pro373Ser restricts conformational changes essential for WASP activity in T-cells. Biochim Biophys Acta. 2014;1842:623-34 pubmed publisher
|
| Reichwald K, Jørgensen T, Tougaard P, Skov S. TL1A induces TCR independent IL-6 and TNF-? production and growth of PLZF? leukocytes. PLoS ONE. 2014;9:e85793 pubmed publisher
|
| Stoler Barak L, Barzilai S, Zauberman A, Alon R. Transendothelial migration of effector T cells across inflamed endothelial barriers does not require heparan sulfate proteoglycans. Int Immunol. 2014;26:315-24 pubmed publisher
|
| Smigielska Czepiel K, van den Berg A, Jellema P, van der Lei R, Bijzet J, Kluiver J, et al. Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs. Genes Immun. 2014;15:115-25 pubmed publisher
|
| Thiruppathi M, Sheng J, Li L, Prabhakar B, Meriggioli M. Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis. J Autoimmun. 2014;52:64-73 pubmed publisher
|
| Renand A, Milpied P, Rossignol J, Bruneau J, Lemonnier F, Dussiot M, et al. Neuropilin-1 expression characterizes T follicular helper (Tfh) cells activated during B cell differentiation in human secondary lymphoid organs. PLoS ONE. 2013;8:e85589 pubmed publisher
|
| Tittarelli A, Mendoza Naranjo A, Farías M, Guerrero I, Ihara F, Wennerberg E, et al. Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity. J Immunol. 2014;192:1313-9 pubmed publisher
|
| Roselli M, Cereda V, di Bari M, Formica V, Spila A, Jochems C, et al. Effects of conventional therapeutic interventions on the number and function of regulatory T cells. Oncoimmunology. 2013;2:e27025 pubmed
|
| Arandi N, Mirshafiey A, Jeddi Tehrani M, Shaghaghi M, Sadeghi B, Abolhassani H, et al. Alteration in frequency and function of CD4?CD25?FOXP3? regulatory T cells in patients with immune thrombocytopenic purpura. Iran J Allergy Asthma Immunol. 2014;13:85-92 pubmed
|
| Tang P, Li L, Zhou Y, Shen C, Kang Y, Yao Y, et al. The preparation of VEGFR1/CD3 bispecific antibody and its specific cytotoxicity against VEGFR1-positive breast cancer cells. Biotechnol Appl Biochem. 2014;61:376-84 pubmed publisher
|
| Gandhi A, Kang J, Havens C, Conklin T, Ning Y, Wu L, et al. Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.). Br J Haematol. 2014;164:811-21 pubmed publisher
|
| Butterfield L, Buffo M. Immunologic monitoring of cancer vaccine trials using the ELISPOT assay. Methods Mol Biol. 2014;1102:71-82 pubmed publisher
|
| Iversen T, Engell Noerregaard L, Ellebaek E, Andersen R, Larsen S, Bjoern J, et al. Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clin Cancer Res. 2014;20:221-32 pubmed publisher
|
| Hellinger R, Koehbach J, Fedchuk H, Sauer B, Huber R, Gruber C, et al. Immunosuppressive activity of an aqueous Viola tricolor herbal extract. J Ethnopharmacol. 2014;151:299-306 pubmed publisher
|
| Zhan H, Gilmour K, Chan L, Farzaneh F, McNicol A, Xu J, et al. Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene. PLoS ONE. 2013;8:e77106 pubmed publisher
|
| Wang F, Chi J, Peng G, Zhou F, Wang J, Li L, et al. Development of virus-specific CD4+ and CD8+ regulatory T cells induced by human herpesvirus 6 infection. J Virol. 2014;88:1011-24 pubmed publisher
|
| Kinoshita S, Kogure A, Taguchi S, Nolan G. Snapin, positive regulator of stimulation- induced Ca²? release through RyR, is necessary for HIV-1 replication in T cells. PLoS ONE. 2013;8:e75297 pubmed publisher
|
| Lin G, Field J, Yu J, Ken R, Neuberg D, Nathan D, et al. NF-?B is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors. PLoS ONE. 2013;8:e74664 pubmed publisher
|
| Suurmond J, Stoop J, Rivellese F, Bakker A, Huizinga T, Toes R. Activation of human basophils by combined toll-like receptor- and Fc?RI-triggering can promote Th2 skewing of naive T helper cells. Eur J Immunol. 2014;44:386-96 pubmed publisher
|
| Jones R, Song H, Xu Y, Garrison K, Buzdin A, Anwar N, et al. LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells. J Virol. 2013;87:13307-20 pubmed publisher
|
| Cheent K, Jamil K, Cassidy S, Liu M, Mbiribindi B, Mulder A, et al. Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94. Proc Natl Acad Sci U S A. 2013;110:16981-6 pubmed publisher
|
| Toledano N, Gur Wahnon D, Ben Yehuda A, Rachmilewitz J. Novel CD47: SIRP? dependent mechanism for the activation of STAT3 in antigen-presenting cell. PLoS ONE. 2013;8:e75595 pubmed publisher
|
| Hayashi K, Jutabha P, Endou H, Sagara H, Anzai N. LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells. J Immunol. 2013;191:4080-5 pubmed publisher
|
| Ankri C, Shamalov K, Horovitz Fried M, Mauer S, Cohen C. Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity. J Immunol. 2013;191:4121-9 pubmed publisher
|
| Kosmaczewska A, Ciszak L, Swierkot J, Szteblich A, Wiland P, Frydecka I. Alterations in both the activatory and inhibitory potential of peripheral blood CD4+ T cells in rheumatoid arthritis patients correlate with disease progression. Pathol Oncol Res. 2014;20:235-43 pubmed publisher
|
| Ma J, Han H, Liu D, Li W, Feng H, Xue X, et al. HER2 as a promising target for cytotoxicity T cells in human melanoma therapy. PLoS ONE. 2013;8:e73261 pubmed publisher
|
| Ahn Y, Kim S, Kim T, Song E, Park M, Heo D. Irradiated and activated autologous PBMCs induce expansion of highly cytotoxic human NK cells in vitro. J Immunother. 2013;36:373-81 pubmed publisher
|
| Kshirsagar S, Binder E, Riedl M, Wechselberger G, Steichen E, Edelbauer M. Enhanced activity of Akt in Teff cells from children with lupus nephritis is associated with reduced induction of tumor necrosis factor receptor-associated factor 6 and increased OX40 expression. Arthritis Rheum. 2013;65:2996-3006 pubmed publisher
|
| Lindenberg J, Oosterhoff D, Sombroek C, Lougheed S, Hooijberg E, Stam A, et al. IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation. PLoS ONE. 2013;8:e70237 pubmed publisher
|
| Helou Y, Nguyen V, Beik S, Salomon A. ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. PLoS ONE. 2013;8:e69641 pubmed publisher
|
| Abrahamsson S, Angelini D, Dubinsky A, Morel E, Oh U, Jones J, et al. Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis. Brain. 2013;136:2888-903 pubmed publisher
|
| Chain J, Martin A, Mack D, Maier L, Palmer B, Fontenot A. Impaired function of CTLA-4 in the lungs of patients with chronic beryllium disease contributes to persistent inflammation. J Immunol. 2013;191:1648-56 pubmed publisher
|
| Larsen S, Munir S, Woetmann A, Frøsig T, Odum N, Svane I, et al. Functional characterization of Foxp3-specific spontaneous immune responses. Leukemia. 2013;27:2332-40 pubmed publisher
|
| Singh H, Figliola M, Dawson M, Olivares S, Zhang L, Yang G, et al. Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells. PLoS ONE. 2013;8:e64138 pubmed publisher
|
| Lindenberg J, van de Ven R, Lougheed S, Zomer A, Santegoets S, Griffioen A, et al. Functional characterization of a STAT3-dependent dendritic cell-derived CD14+ cell population arising upon IL-10-driven maturation. Oncoimmunology. 2013;2:e23837 pubmed
|
| Bhattarai N, McLinden J, Xiang J, Landay A, Chivero E, Stapleton J. GB virus C particles inhibit T cell activation via envelope E2 protein-mediated inhibition of TCR signaling. J Immunol. 2013;190:6351-9 pubmed publisher
|
| Podojil J, Liu L, Marshall S, Chiang M, Goings G, Chen L, et al. B7-H4Ig inhibits mouse and human T-cell function and treats EAE via IL-10/Treg-dependent mechanisms. J Autoimmun. 2013;44:71-81 pubmed publisher
|
| So E, Sallin M, Zhang X, Chan S, Sahni L, Schulze D, et al. A high throughput method for enrichment of natural killer cells and lymphocytes and assessment of in vitro cytotoxicity. J Immunol Methods. 2013;394:40-8 pubmed publisher
|
| Zhai R, Jiang A, Wang H, Ma L, Ren X, Jiang J, et al. Histamine enhances HIV-1-induced modulation of dendritic cells to skew naïve T cell differentiation toward regulatory T cells. Virology. 2013;442:163-72 pubmed publisher
|
| Qiu X, Zhang M, Yang X, Hong N, Yu C. Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis. J Crohns Colitis. 2013;7:e558-68 pubmed publisher
|
| Arandi N, Mirshafiey A, Jeddi Tehrani M, Abolhassani H, Sadeghi B, Mirminachi B, et al. Evaluation of CD4+CD25+FOXP3+ regulatory T cells function in patients with common variable immunodeficiency. Cell Immunol. 2013;281:129-33 pubmed publisher
|
| Devaud C, Rousseau B, Netzer S, Pitard V, Paroissin C, Khairallah C, et al. Anti-metastatic potential of human V?1(+) ?? T cells in an orthotopic mouse xenograft model of colon carcinoma. Cancer Immunol Immunother. 2013;62:1199-210 pubmed publisher
|
| Dokić J, Tomic S, Markovic M, Milosavljević P, Colic M. Mesenchymal stem cells from periapical lesions modulate differentiation and functional properties of monocyte-derived dendritic cells. Eur J Immunol. 2013;43:1862-72 pubmed publisher
|
| Bloch O, Crane C, Kaur R, Safaee M, Rutkowski M, Parsa A. Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages. Clin Cancer Res. 2013;19:3165-75 pubmed publisher
|
| Pihl M, Akerman L, Axelsson S, Chéramy M, Hjorth M, Mallone R, et al. Regulatory T cell phenotype and function 4 years after GAD-alum treatment in children with type 1 diabetes. Clin Exp Immunol. 2013;172:394-402 pubmed publisher
|
| Zunino S, Storms D, Freytag T, Mackey B, Zhao L, Gouffon J, et al. Dietary strawberries increase the proliferative response of CD3/CD28-activated CD8? T cells and the production of TNF-? in lipopolysaccharide-stimulated monocytes from obese human subjects. Br J Nutr. 2013;110:2011-9 pubmed publisher
|
| Rodriguez Plata M, Puigdomènech I, Izquierdo Useros N, Puertas M, Carrillo J, Erkizia I, et al. The infectious synapse formed between mature dendritic cells and CD4(+) T cells is independent of the presence of the HIV-1 envelope glycoprotein. Retrovirology. 2013;10:42 pubmed publisher
|
| Koelsch K, Wang Y, Maier Moore J, Sawalha A, Wren J. GFP affects human T cell activation and cytokine production following in vitro stimulation. PLoS ONE. 2013;8:e50068 pubmed publisher
|
| Schwarz A, Schumacher M, Pfaff D, Schumacher K, Jarius S, Balint B, et al. Fine-tuning of regulatory T cell function: the role of calcium signals and naive regulatory T cells for regulatory T cell deficiency in multiple sclerosis. J Immunol. 2013;190:4965-70 pubmed publisher
|
| Jia L, Zhu L, WANG J, WANG X, Chen J, Song L, et al. Methylation of FOXP3 in regulatory T cells is related to the severity of coronary artery disease. Atherosclerosis. 2013;228:346-52 pubmed publisher
|
| Chicaybam L, Sodré A, Curzio B, Bonamino M. An efficient low cost method for gene transfer to T lymphocytes. PLoS ONE. 2013;8:e60298 pubmed publisher
|
| You D, Marr N, Saravia J, Shrestha B, Lee G, Turvey S, et al. IL-4R? on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. J Leukoc Biol. 2013;93:933-42 pubmed publisher
|
| Melton A, Melrose J, Alajoki L, Privat S, Cho H, Brown N, et al. Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation. PLoS ONE. 2013;8:e58966 pubmed publisher
|
| Miller T, Kaur S, Ivins O Keefe K, Roberts D. Thrombospondin-1 is a CD47-dependent endogenous inhibitor of hydrogen sulfide signaling in T cell activation. Matrix Biol. 2013;32:316-24 pubmed publisher
|
| Lin J, Chang W, Dong J, Zhang F, Mohabeer N, Kushwaha K, et al. Thymic stromal lymphopoietin over-expressed in human atherosclerosis: potential role in Th17 differentiation. Cell Physiol Biochem. 2013;31:305-18 pubmed publisher
|
| Bidad K, Salehi E, Jamshidi A, Saboor Yaraghi A, Oraei M, Meysamie A, et al. Effect of all-transretinoic acid on Th17 and T regulatory cell subsets in patients with ankylosing spondylitis. J Rheumatol. 2013;40:476-83 pubmed publisher
|
| Huang W, Morales J, Gazivoda V, Lai J, Qi Q, August A. The zinc-binding region of IL-2 inducible T cell kinase (Itk) is required for interaction with G?13 and activation of serum response factor. Int J Biochem Cell Biol. 2013;45:1074-82 pubmed publisher
|
| Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, et al. Functional characterization of EZH2? reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression. Epigenetics Chromatin. 2013;6:3 pubmed publisher
|
| Hirayama M, Nishikawa H, Nagata Y, Tsuji T, Kato T, Kageyama S, et al. Overcoming regulatory T-cell suppression by a lyophilized preparation of Streptococcus pyogenes. Eur J Immunol. 2013;43:989-1000 pubmed publisher
|
| Katz S, Burga R, Naheed S, Licata L, Thorn M, Osgood D, et al. Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor. J Transl Med. 2013;11:46 pubmed publisher
|
| Palin A, Ramachandran V, Acharya S, Lewis D. Human neonatal naive CD4+ T cells have enhanced activation-dependent signaling regulated by the microRNA miR-181a. J Immunol. 2013;190:2682-91 pubmed publisher
|
| Yeh C, Yeh T, Jung C, Chen P, Lien H, Chia J. Activated human nasal epithelial cells modulate specific antibody response against bacterial or viral antigens. PLoS ONE. 2013;8:e55472 pubmed publisher
|
| Sierich H, Eiermann T. Comparing individual NK cell activity in vitro. Curr Protoc Immunol. 2013;Chapter 14:Unit 14.32. pubmed publisher
|
| Cattaneo F, Recher M, Masneri S, Baxi S, Fiorini C, Antonelli F, et al. Hypomorphic Janus kinase 3 mutations result in a spectrum of immune defects, including partial maternal T-cell engraftment. J Allergy Clin Immunol. 2013;131:1136-45 pubmed publisher
|
| Mor F, Cohen I. Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin. Proc Natl Acad Sci U S A. 2013;110:2981-6 pubmed publisher
|
| Fu Z, Zuo Y, Li D, Xu W, Li D, Chen H, et al. The crosstalk: Tumor-infiltrating lymphocytes rich in regulatory T cells suppressed cancer-associated fibroblasts. Acta Oncol. 2013;52:1760-70 pubmed publisher
|
| Kim E, Ahn Y, Kim S, Kim T, Keam B, Heo D. Ex vivo activation and expansion of natural killer cells from patients with advanced cancer with feeder cells from healthy volunteers. Cytotherapy. 2013;15:231-241.e1 pubmed publisher
|
| Huen N, Pang A, Tucker J, Lee T, Vergati M, Jochems C, et al. Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer. Int J Cancer. 2013;133:373-82 pubmed publisher
|
| Anangi R, Koshy S, Huq R, Beeton C, Chuang W, King G. Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers. PLoS ONE. 2012;7:e52965 pubmed publisher
|
| Wachstein J, Tischer S, Figueiredo C, Limbourg A, Falk C, Immenschuh S, et al. HSP70 enhances immunosuppressive function of CD4(+)CD25(+)FoxP3(+) T regulatory cells and cytotoxicity in CD4(+)CD25(-) T cells. PLoS ONE. 2012;7:e51747 pubmed publisher
|
| Qiu Y, Huang Y, Chen J, Qiao D, Zeng G, Cai J. Depletion of IL-22 during culture enhanced antigen-driven IFN-? production by CD4(+)T cells from patients with active TB. Immunol Lett. 2013;150:48-53 pubmed publisher
|
| Cosgrove C, Ussher J, Rauch A, Gärtner K, Kurioka A, Hühn M, et al. Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection. Blood. 2013;121:951-61 pubmed publisher
|
| García Blesa A, Klossowicz M, López Osuna C, Martínez Florensa M, Malissen B, García Cózar F, et al. The membrane adaptor LAT is proteolytically cleaved following Fas engagement in a tyrosine phosphorylation-dependent fashion. Biochem J. 2013;450:511-21 pubmed publisher
|
| Zha B, Wang L, Liu X, Liu J, Chen Z, Xu J, et al. Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves' disease. PLoS ONE. 2012;7:e49835 pubmed publisher
|
| Li M, Cao W, Liu H, Zhang W, Liu X, Cai Z, et al. MCPIP1 down-regulates IL-2 expression through an ARE-independent pathway. PLoS ONE. 2012;7:e49841 pubmed publisher
|
| Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
|
| Olson B, Jankowska Gan E, Becker J, Vignali D, Burlingham W, McNeel D. Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. J Immunol. 2012;189:5590-601 pubmed publisher
|
| Thiruppathi M, Rowin J, Ganesh B, Sheng J, Prabhakar B, Meriggioli M. Impaired regulatory function in circulating CD4(+)CD25(high)CD127(low/-) T cells in patients with myasthenia gravis. Clin Immunol. 2012;145:209-23 pubmed publisher
|
| Ebert L, MacRaild S, Zanker D, Davis I, Cebon J, Chen W. A cancer vaccine induces expansion of NY-ESO-1-specific regulatory T cells in patients with advanced melanoma. PLoS ONE. 2012;7:e48424 pubmed publisher
|
| Jeffery L, Wood A, Qureshi O, Hou T, Gardner D, Briggs Z, et al. Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses. J Immunol. 2012;189:5155-64 pubmed publisher
|
| Cao L, Ding Y, Hung N, Yu K, Ritz A, Raphael B, et al. Quantitative phosphoproteomics reveals SLP-76 dependent regulation of PAG and Src family kinases in T cells. PLoS ONE. 2012;7:e46725 pubmed publisher
|
| McIver Z, Melenhorst J, Wu C, Grim A, Ito S, Cho I, et al. Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant. Haematologica. 2013;98:346-52 pubmed publisher
|
| Pennington M, Harunur Rashid M, Tajhya R, Beeton C, Kuyucak S, Norton R. A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3. FEBS Lett. 2012;586:3996-4001 pubmed publisher
|
| Huber Ruano I, Errasti Murugarren E, Godoy V, Vera A, Andreu A, Garcia Arumi E, et al. Functional outcome of a novel SLC29A3 mutation identified in a patient with H syndrome. Biochem Biophys Res Commun. 2012;428:532-7 pubmed publisher
|
| Bahri R, Bollinger A, Bollinger T, Orinska Z, Bulfone Paus S. Ectonucleotidase CD38 demarcates regulatory, memory-like CD8+ T cells with IFN-?-mediated suppressor activities. PLoS ONE. 2012;7:e45234 pubmed publisher
|
| Hock B, Taylor K, Cross N, Kettle A, Hampton M, McKenzie J. Effect of activated human polymorphonuclear leucocytes on T lymphocyte proliferation and viability. Immunology. 2012;137:249-58 pubmed publisher
|
| Larochelle C, Cayrol R, Kebir H, Alvarez J, Lécuyer M, Ifergan I, et al. Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system. Brain. 2012;135:2906-24 pubmed publisher
|
| Durrieu L, Gregoire Gauthier J, Dieng M, Fontaine F, Le Deist F, Haddad E. Human interferon-alpha increases the cytotoxic effect of CD56(+) cord blood-derived cytokine-induced killer cells on human B-acute lymphoblastic leukemia cell lines. Cytotherapy. 2012;14:1245-57 pubmed publisher
|
| Chueh F, Yu C. Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged STAT activation through autocrine/paracrine stimulation in human primary T cells. Biochem Biophys Res Commun. 2012;426:242-6 pubmed publisher
|
| Bandyopadhyay G, Bankey P, Miller Graziano C. Trauma patients' elevated tumor necrosis related apoptosis inducing ligand (TRAIL) contributes to increased T cell apoptosis. Clin Immunol. 2012;145:44-54 pubmed publisher
|
| Rowin J, Thiruppathi M, Arhebamen E, Sheng J, Prabhakar B, Meriggioli M. Granulocyte macrophage colony-stimulating factor treatment of a patient in myasthenic crisis: effects on regulatory T cells. Muscle Nerve. 2012;46:449-53 pubmed publisher
|
| Xiong Y, Khanna S, Grzenda A, Sarmento O, Svingen P, Lomberk G, et al. Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner. J Biol Chem. 2012;287:34372-85 pubmed publisher
|
| Feldmann A, Arndt C, Töpfer K, Stamova S, Krone F, Cartellieri M, et al. Novel humanized and highly efficient bispecific antibodies mediate killing of prostate stem cell antigen-expressing tumor cells by CD8+ and CD4+ T cells. J Immunol. 2012;189:3249-59 pubmed publisher
|
| Forget M, Huon Y, Reuben A, Grange C, Liberman M, Martin J, et al. Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype. PLoS ONE. 2012;7:e41074 pubmed publisher
|
| Zhang T, Wu M, Sentman C. An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo. J Immunol. 2012;189:2290-9 pubmed publisher
|
| Bhattarai N, McLinden J, Xiang J, Kaufman T, Stapleton J. GB virus C envelope protein E2 inhibits TCR-induced IL-2 production and alters IL-2-signaling pathways. J Immunol. 2012;189:2211-6 pubmed publisher
|
| Venigalla R, Guttikonda P, Eckstein V, Ho A, Sertel S, Lorenz H, et al. Identification of a human Th1-like IFN?-secreting Treg subtype deriving from effector T cells. J Autoimmun. 2012;39:377-87 pubmed publisher
|
| Chemin K, Bohineust A, Dogniaux S, Tourret M, Guegan S, Miro F, et al. Cytokine secretion by CD4+ T cells at the immunological synapse requires Cdc42-dependent local actin remodeling but not microtubule organizing center polarity. J Immunol. 2012;189:2159-68 pubmed publisher
|
| Kim H, Long E. Complementary phosphorylation sites in the adaptor protein SLP-76 promote synergistic activation of natural killer cells. Sci Signal. 2012;5:ra49 pubmed publisher
|
| Lee W, Yao T, Yeh K, Chen L, Ou L, Huang J. Stronger Toll-like receptor 1/2, 4, and 7/8 but less 9 responses in peripheral blood mononuclear cells in non-infectious exacerbated asthmatic children. Immunobiology. 2013;218:192-200 pubmed publisher
|
| Alangari A, Alsultan A, Adly N, Massaad M, Kiani I, Aljebreen A, et al. LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol. 2012;130:481-8.e2 pubmed publisher
|
| Qin Y, Li Y, Jiang A, Jiang J, Wang J. Stimulation of Cryptococcus neoformans isolated from skin lesion of AIDS patient matures dendritic cells and promotes HIV-1 trans-infection. Biochem Biophys Res Commun. 2012;423:709-14 pubmed publisher
|
| Hill D, Eastaff Leung N, Bresatz Atkins S, Warner N, Ruitenberg J, Krumbiegel D, et al. Inhibition of activation induced CD154 on CD4+ CD25- cells: a valid surrogate for human Treg suppressor function. Immunol Cell Biol. 2012;90:812-21 pubmed publisher
|
| Bonacci B, Edwards B, Jia S, Williams C, Hessner M, Gauld S, et al. Requirements for growth and IL-10 expression of highly purified human T regulatory cells. J Clin Immunol. 2012;32:1118-28 pubmed publisher
|
| Berk E, Muthuswamy R, Kalinski P. Lymphocyte-polarized dendritic cells are highly effective in inducing tumor-specific CTLs. Vaccine. 2012;30:6216-24 pubmed publisher
|
| Torikai H, Reik A, Liu P, Zhou Y, Zhang L, Maiti S, et al. A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR. Blood. 2012;119:5697-705 pubmed publisher
|
| Nicholson I, Mavrangelos C, Bird D, Bresatz Atkins S, Eastaff Leung N, Grose R, et al. PI16 is expressed by a subset of human memory Treg with enhanced migration to CCL17 and CCL20. Cell Immunol. 2012;275:12-8 pubmed publisher
|
| Xie X, Gao M, Zhang B, Wang M, Wang J. Post-transcriptional CD59 gene silencing by siRNAs induces enhanced human T lymphocyte response to tumor cell lysate-loaded DCs. Cell Immunol. 2012;274:1-11 pubmed publisher
|
| Hsu S, Wang L, Yao C, Lai H, Chan K, Liu B, et al. Mesenchymal stem cells promote neutrophil activation by inducing IL-17 production in CD4+ CD45RO+ T cells. Immunobiology. 2013;218:90-5 pubmed publisher
|
| Sage P, Varghese L, Martinelli R, Sciuto T, Kamei M, Dvorak A, et al. Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells. J Immunol. 2012;188:3686-99 pubmed publisher
|
| Poulin L, Reyal Y, Uronen Hansson H, Schraml B, Sancho D, Murphy K, et al. DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues. Blood. 2012;119:6052-62 pubmed publisher
|
| Kroenke M, Eto D, Locci M, Cho M, Davidson T, Haddad E, et al. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol. 2012;188:3734-44 pubmed publisher
|
| Mujib S, Jones R, Lo C, Aidarus N, Clayton K, Sakhdari A, et al. Antigen-independent induction of Tim-3 expression on human T cells by the common ?-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway. J Immunol. 2012;188:3745-56 pubmed publisher
|
| Phillips M, Wallace K, Dickerson S, Miller M, Verhoeven A, Martin J, et al. Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses. Invest Ophthalmol Vis Sci. 2012;53:2007-19 pubmed publisher
|
| Bikker A, Moret F, Kruize A, Bijlsma J, Lafeber F, van Roon J. IL-7 drives Th1 and Th17 cytokine production in patients with primary SS despite an increase in CD4 T cells lacking the IL-7R?. Rheumatology (Oxford). 2012;51:996-1005 pubmed publisher
|
| Fu G, Chen X, Hu H, Yang H, Xu X, Qiu T, et al. Emergence of peripheral CD3+CD56+ cytokine-induced killer cell in HIV-1-infected Chinese children. Int Immunol. 2012;24:197-206 pubmed publisher
|
| Owen D, Williamson D, Magenau A, Gaus K. Optical techniques for imaging membrane domains in live cells (live-cell palm of protein clustering). Methods Enzymol. 2012;504:221-35 pubmed publisher
|
| Gaspar Ramírez O, Pérez Vázquez F, Pruneda Álvarez L, Orta García S, Gonzalez Amaro R, Pérez Maldonado I. Effect of polychlorinated biphenyls 118 and 153 on Th1/Th2 cells differentiation. Immunopharmacol Immunotoxicol. 2012;34:627-32 pubmed publisher
|
| Ioannou M, Alissafi T, Lazaridis I, Deraos G, Matsoukas J, Gravanis A, et al. Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease. J Immunol. 2012;188:1136-46 pubmed publisher
|
| Wang T, Huang C, Lopez Coral A, Slentz Kesler K, Xiao M, Wherry E, et al. K12/SECTM1, an interferon-? regulated molecule, synergizes with CD28 to costimulate human T cell proliferation. J Leukoc Biol. 2012;91:449-59 pubmed publisher
|
| Gorska M, Alam R. A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia. Blood. 2012;119:1399-406 pubmed publisher
|
| Miller T, Wang E, Gould S, Stein E, Kaur S, Lim L, et al. Hydrogen sulfide is an endogenous potentiator of T cell activation. J Biol Chem. 2012;287:4211-21 pubmed publisher
|
| Uzana R, Eisenberg G, Sagi Y, Frankenburg S, Merims S, Amariglio N, et al. Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones. J Immunol. 2012;188:632-40 pubmed publisher
|
| Kashiwakura J, Ando T, Matsumoto K, Kimura M, Kitaura J, Matho M, et al. Histamine-releasing factor has a proinflammatory role in mouse models of asthma and allergy. J Clin Invest. 2012;122:218-28 pubmed publisher
|
| Koreth J, Matsuoka K, Kim H, McDonough S, Bindra B, Alyea E, et al. Interleukin-2 and regulatory T cells in graft-versus-host disease. N Engl J Med. 2011;365:2055-66 pubmed publisher
|
| McAlpine S, Issekutz T, Marshall J. Virus stimulation of human mast cells results in the recruitment of CD56? T cells by a mechanism dependent on CCR5 ligands. FASEB J. 2012;26:1280-9 pubmed publisher
|
| Kliche S, Worbs T, Wang X, Degen J, Patzak I, Meineke B, et al. CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules. Blood. 2012;119:777-85 pubmed publisher
|
| Qin Y, Li Y, Liu W, Tian R, Guo Q, Li S, et al. Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells. PLoS ONE. 2011;6:e27609 pubmed publisher
|
| Lee D, Jessen B. Off-target immune cell toxicity caused by AG-012986, a pan-CDK inhibitor, is associated with inhibition of p38 MAPK phosphorylation. J Biochem Mol Toxicol. 2012;26:101-8 pubmed publisher
|
| Lin J, Stein E, Wong M, Kalpathy K, Su L, Utz P, et al. Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis. Clin Immunol. 2012;142:127-38 pubmed publisher
|
| Dhir V, Fort M, Mahmood A, Higbee R, Warren W, Narayanan P, et al. A predictive biomimetic model of cytokine release induced by TGN1412 and other therapeutic monoclonal antibodies. J Immunotoxicol. 2012;9:34-42 pubmed publisher
|
| Taylor A, Cross E, Llewelyn M. Induction of contact-dependent CD8(+) regulatory T cells through stimulation with staphylococcal and streptococcal superantigens. Immunology. 2012;135:158-67 pubmed publisher
|
| Schaeuble K, Hauser M, Singer E, Groettrup M, Legler D. Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration. J Immunol. 2011;187:5645-52 pubmed publisher
|
| Voelkel C, Galla M, Dannhauser P, Maetzig T, Sodeik B, Schambach A, et al. Pseudotype-independent nonspecific uptake of gammaretroviral and lentiviral particles in human cells. Hum Gene Ther. 2012;23:274-86 pubmed publisher
|
| Dolff S, Abdulahad W, Westra J, Doornbos van der Meer B, Limburg P, Kallenberg C, et al. Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus. Arthritis Res Ther. 2011;13:R157 pubmed publisher
|
| Tacke R, Lee H, Goh C, Courtney J, Polyak S, Rosen H, et al. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology. 2012;55:343-53 pubmed publisher
|
| Kirshberg S, Izhar U, Amir G, Demma J, Vernea F, Beider K, et al. Involvement of CCR6/CCL20/IL-17 axis in NSCLC disease progression. PLoS ONE. 2011;6:e24856 pubmed publisher
|
| Williams K, Dotson A, Otto A, Kohlmeier J, Benedict S. Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation. Cell Immunol. 2011;271:418-27 pubmed publisher
|
| Nunes Cabaço H, Caramalho I, Sepúlveda N, Sousa A. Differentiation of human thymic regulatory T cells at the double positive stage. Eur J Immunol. 2011;41:3604-14 pubmed publisher
|
| Germain C, Meier A, Jensen T, Knapnougel P, Poupon G, Lazzari A, et al. Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-? contributes to modulate immune responses. J Biol Chem. 2011;286:37964-75 pubmed publisher
|
| Duske H, Sputtek A, Binder T, Kroger N, Schrepfer S, Eiermann T. Assessment of physiologic natural killer cell cytotoxicity in vitro. Hum Immunol. 2011;72:1007-12 pubmed publisher
|
| Wiemer A, Hegde S, Gumperz J, Huttenlocher A. A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist. J Immunol. 2011;187:3663-70 pubmed publisher
|
| Shaw J, Hunt P, Critchfield J, McConnell D, Garcia J, Pollard R, et al. Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers. J Virol. 2011;85:11422-34 pubmed publisher
|
| Hioe C, Tuen M, Vasiliver Shamis G, Alvarez Y, Prins K, Banerjee S, et al. HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA). PLoS ONE. 2011;6:e23202 pubmed publisher
|
| Landrigan A, Wong M, Utz P. CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol. 2011;187:3033-43 pubmed publisher
|
| Mendoza Naranjo A, Bouma G, Pereda C, Ramírez M, Webb K, Tittarelli A, et al. Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation. J Immunol. 2011;187:3121-32 pubmed publisher
|
| Wehrens E, Mijnheer G, Duurland C, Klein M, Meerding J, van Loosdregt J, et al. Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells. Blood. 2011;118:3538-48 pubmed publisher
|
| Ye Q, Loisiou M, Levine B, Suhoski M, Riley J, June C, et al. Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes. J Transl Med. 2011;9:131 pubmed publisher
|
| Hilchey S, Rosenberg A, Hyrien O, Secor Socha S, Cochran M, Brady M, et al. Follicular lymphoma tumor-infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation. Blood. 2011;118:3591-602 pubmed publisher
|
| Suárez Fueyo A, Barber D, Martinez Ara J, Zea Mendoza A, Carrera A. Enhanced phosphoinositide 3-kinase ? activity is a frequent event in systemic lupus erythematosus that confers resistance to activation-induced T cell death. J Immunol. 2011;187:2376-85 pubmed publisher
|
| Pollara J, Hart L, Brewer F, Pickeral J, Packard B, Hoxie J, et al. High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. Cytometry A. 2011;79:603-12 pubmed publisher
|
| Birzele F, Fauti T, Stahl H, Lenter M, Simon E, Knebel D, et al. Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human. Nucleic Acids Res. 2011;39:7946-60 pubmed publisher
|
| Haufe S, Haug M, Schepp C, Kuemmerle Deschner J, Hansmann S, Rieber N, et al. Impaired suppression of synovial fluid CD4+CD25- T cells from patients with juvenile idiopathic arthritis by CD4+CD25+ Treg cells. Arthritis Rheum. 2011;63:3153-62 pubmed publisher
|
| Correia D, Fogli M, Hudspeth K, da Silva M, Mavilio D, Silva Santos B. Differentiation of human peripheral blood V?1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells. Blood. 2011;118:992-1001 pubmed publisher
|
| Mkhikian H, Grigorian A, Li C, Chen H, Newton B, Zhou R, et al. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nat Commun. 2011;2:334 pubmed publisher
|
| Gründemann C, Gruber C, Hertrampf A, Zehl M, Kopp B, Huber R. An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes. J Ethnopharmacol. 2011;136:444-51 pubmed publisher
|
| de la Fuente M, Recher M, Rider N, Strauss K, Morton D, Adair M, et al. Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia. J Allergy Clin Immunol. 2011;128:139-146 pubmed publisher
|
| Cereda V, Vergati M, Huen N, di Bari M, Jochems C, Intrivici C, et al. Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-specific effectors to regulatory T cells. Vaccine. 2011;29:4992-9 pubmed publisher
|
| Merims S, Li X, Joe B, Dokouhaki P, Han M, Childs R, et al. Anti-leukemia effect of ex vivo expanded DNT cells from AML patients: a potential novel autologous T-cell adoptive immunotherapy. Leukemia. 2011;25:1415-22 pubmed publisher
|
| Wege A, Ernst W, Eckl J, Frankenberger B, Vollmann Zwerenz A, Männel D, et al. Humanized tumor mice--a new model to study and manipulate the immune response in advanced cancer therapy. Int J Cancer. 2011;129:2194-206 pubmed publisher
|
| Ferrari G, Pollara J, Kozink D, Harms T, Drinker M, Freel S, et al. An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. J Virol. 2011;85:7029-36 pubmed publisher
|
| Brembilla N, Ramirez J, Chicheportiche R, Sorg O, Saurat J, Chizzolini C. In vivo dioxin favors interleukin-22 production by human CD4+ T cells in an aryl hydrocarbon receptor (AhR)-dependent manner. PLoS ONE. 2011;6:e18741 pubmed publisher
|
| Barber A, Sentman C. NKG2D receptor regulates human effector T-cell cytokine production. Blood. 2011;117:6571-81 pubmed publisher
|
| Kim S, Han S, Withers D, Gaspal F, Bae J, Baik S, et al. CD117? CD3? CD56? OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues. Eur J Immunol. 2011;41:1563-72 pubmed publisher
|
| Jin Z, Maiti S, Huls H, Singh H, Olivares S, Mátés L, et al. The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor. Gene Ther. 2011;18:849-56 pubmed publisher
|
| Giordano Attianese G, Marin V, Hoyos V, Savoldo B, Pizzitola I, Tettamanti S, et al. In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor. Blood. 2011;117:4736-45 pubmed publisher
|
| Zhu Y, Gumlaw N, Karman J, Zhao H, Zhang J, Jiang J, et al. Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage. J Biol Chem. 2011;286:14787-94 pubmed publisher
|
| Mao C, Wang S, Xiao Y, Xu J, Jiang Q, Jin M, et al. Impairment of regulatory capacity of CD4+CD25+ regulatory T cells mediated by dendritic cell polarization and hyperthyroidism in Graves' disease. J Immunol. 2011;186:4734-43 pubmed publisher
|
| Quandt D, Fiedler E, Boettcher D, Marsch W, Seliger B. B7-h4 expression in human melanoma: its association with patients' survival and antitumor immune response. Clin Cancer Res. 2011;17:3100-11 pubmed publisher
|
| Tang T, Song Y, Ding Y, Liao Y, Yu X, Du R, et al. Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J Lipid Res. 2011;52:1023-32 pubmed publisher
|
| Coffelt S, Chen Y, Muthana M, Welford A, Tal A, Scholz A, et al. Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. J Immunol. 2011;186:4183-90 pubmed publisher
|
| Bosè F, Raeli L, Garutti C, Frigerio E, Cozzi A, Crimi M, et al. Dual role of anti-TNF therapy: enhancement of TCR-mediated T cell activation in peripheral blood and inhibition of inflammation in target tissues. Clin Immunol. 2011;139:164-76 pubmed publisher
|
| Hönscheid A, Dubben S, Rink L, Haase H. Zinc differentially regulates mitogen-activated protein kinases in human T cells. J Nutr Biochem. 2012;23:18-26 pubmed publisher
|
| Kwajah M M S, Mustafa N, Holme A, Pervaiz S, Schwarz H. Biphasic activity of CD137 ligand-stimulated monocytes on T cell apoptosis and proliferation. J Leukoc Biol. 2011;89:707-20 pubmed publisher
|
| Moens E, Brouwer M, Dimova T, Goldman M, Willems F, Vermijlen D. IL-23R and TCR signaling drives the generation of neonatal Vgamma9Vdelta2 T cells expressing high levels of cytotoxic mediators and producing IFN-gamma and IL-17. J Leukoc Biol. 2011;89:743-52 pubmed publisher
|
| Wei J, Wu A, Kong L, Wang Y, Fuller G, Fokt I, et al. Hypoxia potentiates glioma-mediated immunosuppression. PLoS ONE. 2011;6:e16195 pubmed publisher
|
| Hayashi K, Kamikawa Y. HSP90 is crucial for regulation of LAT expression in activated T cells. Mol Immunol. 2011;48:941-6 pubmed publisher
|
| Banerjee S, Lin C, Skinner K, Schiffhauer L, Peacock J, Hicks D, et al. Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression. Cancer Res. 2011;71:318-27 pubmed publisher
|
| Libri V, Azevedo R, Jackson S, Di Mitri D, Lachmann R, Fuhrmann S, et al. Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+CD45RA+CD27+ T cells: the potential involvement of interleukin-7 in this process. Immunology. 2011;132:326-39 pubmed publisher
|
| Bjoern J, Brimnes M, Andersen M, thor Straten P, Svane I. Changes in peripheral blood level of regulatory T cells in patients with malignant melanoma during treatment with dendritic cell vaccination and low-dose IL-2. Scand J Immunol. 2011;73:222-33 pubmed publisher
|
| Zloza A, Jagoda M, Lyons G, Graves M, Kohlhapp F, O Sullivan J, et al. CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-? (TGF-?)-mediated suppression. Cancer Immunol Immunother. 2011;60:291-7 pubmed publisher
|
| Rivet C, Hill A, Lu H, Kemp M. Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers. Mol Cell Proteomics. 2011;10:M110.003921 pubmed publisher
|
| Holmes T, El Sherbiny Y, Davison A, Clough S, Blair G, Cook G. A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells. J Immunol. 2011;186:1538-45 pubmed publisher
|
| Comin Anduix B, Chodon T, Sazegar H, Matsunaga D, Mock S, Jalil J, et al. The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations. Clin Cancer Res. 2010;16:6040-8 pubmed publisher
|
| Baeke F, Korf H, Overbergh L, Verstuyf A, Thorrez L, Van Lommel L, et al. The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation. J Immunol. 2011;186:132-42 pubmed publisher
|
| Kudela P, Sun Z, Fourcade J, Janjic B, Kirkwood J, Maillere B, et al. Epitope hierarchy of spontaneous CD4+ T cell responses to LAGE-1. J Immunol. 2011;186:312-22 pubmed publisher
|
| Tario J, Muirhead K, Pan D, Munson M, Wallace P. Tracking immune cell proliferation and cytotoxic potential using flow cytometry. Methods Mol Biol. 2011;699:119-64 pubmed publisher
|
| Cubillos Ruiz J, Martinez D, Scarlett U, Rutkowski M, Nesbeth Y, Camposeco Jacobs A, et al. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. Oncotarget. 2010;1:329-38 pubmed
|
| Taylor A, Llewelyn M. Superantigen-induced proliferation of human CD4+CD25- T cells is followed by a switch to a functional regulatory phenotype. J Immunol. 2010;185:6591-8 pubmed publisher
|
| Brimnes M, Vangsted A, Knudsen L, Gimsing P, Gang A, Johnsen H, et al. Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR?/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma. Scand J Immunol. 2010;72:540-7 pubmed publisher
|
| Merims S, Dokouhaki P, Joe B, Zhang L. Human V?1-T cells regulate immune responses by targeting autologous immature dendritic cells. Hum Immunol. 2011;72:32-6 pubmed publisher
|
| Maier E, Hebenstreit D, Posselt G, Hammerl P, Duschl A, Horejs Hoeck J. Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling. J Biol Chem. 2011;286:919-28 pubmed publisher
|
| Parmigiani A, Pallin M, Schmidtmayerova H, Lichtenheld M, Pahwa S. Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells. Hum Immunol. 2011;72:115-23 pubmed publisher
|
| Li Y, Kurlander R. Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: differing impact on CD8 T cell phenotype and responsiveness to restimulation. J Transl Med. 2010;8:104 pubmed publisher
|
| Busuttil V, Droin N, McCormick L, Bernassola F, Candi E, Melino G, et al. NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2. Proc Natl Acad Sci U S A. 2010;107:18061-6 pubmed publisher
|
| Comin Anduix B, Sazegar H, Chodon T, Matsunaga D, Jalil J, von Euw E, et al. Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma. PLoS ONE. 2010;5:e12711 pubmed publisher
|
| Kingeter L, Paul S, Maynard S, Cartwright N, Schaefer B. Cutting edge: TCR ligation triggers digital activation of NF-kappaB. J Immunol. 2010;185:4520-4 pubmed publisher
|
| Ferrandi C, Richard F, Tavano P, Hauben E, Barbié V, Gotteland J, et al. Characterization of immune cell subsets during the active phase of multiple sclerosis reveals disease and c-Jun N-terminal kinase pathway biomarkers. Mult Scler. 2011;17:43-56 pubmed publisher
|
| Wang H, Zeng X, Fan Z, Lim B. RhoH modulates pre-TCR and TCR signalling by regulating LCK. Cell Signal. 2011;23:249-58 pubmed publisher
|
| Wu S, Yang C, Guo S, Fei L, Luo N, Fu X, et al. Stimulation of B7-H1 in hepatocarcinoma cells by hepatitis B virus X antigen. Immunol Invest. 2010;39:754-69 pubmed publisher
|
| Lindsey J, Hatfield L. Epstein-Barr virus and multiple sclerosis: cellular immune response and cross-reactivity. J Neuroimmunol. 2010;229:238-42 pubmed publisher
|
| Sarrabayrouse G, Corvaisier M, Ouisse L, Bossard C, Le Mevel B, Potiron L, et al. Tumor-reactive CD4+ CD8??+ CD103+ ??T cells: a prevalent tumor-reactive T-cell subset in metastatic colorectal cancers. Int J Cancer. 2011;128:2923-32 pubmed publisher
|
| van Roon J, Hartgring S, van der Wurff Jacobs K, Bijlsma J, Lafeber F. Numbers of CD25+Foxp3+ T cells that lack the IL-7 receptor are increased intra-articularly and have impaired suppressive function in RA patients. Rheumatology (Oxford). 2010;49:2084-9 pubmed publisher
|
| De Meester J, Calvez R, Valitutti S, Dupré L. The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets. J Leukoc Biol. 2010;88:1031-40 pubmed publisher
|
| Kaur G, Goodall J, Jarvis L, Hill Gaston J. Characterisation of Foxp3 splice variants in human CD4+ and CD8+ T cells--identification of Foxp3?7 in human regulatory T cells. Mol Immunol. 2010;48:321-32 pubmed publisher
|
| Marquet J, Lasoudris F, Cousin C, Puiffe M, Martin Garcia N, Baud V, et al. Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes. Eur J Immunol. 2010;40:2557-68 pubmed publisher
|
| Deng L, Zhang H, Luan Y, Zhang J, Xing Q, Dong S, et al. Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients. Clin Cancer Res. 2010;16:4105-12 pubmed publisher
|
| Wu A, Wei J, Kong L, Wang Y, Priebe W, Qiao W, et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol. 2010;12:1113-25 pubmed publisher
|
| Prado C, Gómez J, Lopez P, de Paz B, Gutierrez C, Suarez A. Dexamethasone upregulates FOXP3 expression without increasing regulatory activity. Immunobiology. 2011;216:386-92 pubmed publisher
|
| Sylvester M, Kliche S, Lange S, Geithner S, Klemm C, Schlosser A, et al. Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells. PLoS ONE. 2010;5:e11708 pubmed publisher
|
| Bollinger T, Bollinger A, Naujoks J, Lange T, Solbach W. The influence of regulatory T cells and diurnal hormone rhythms on T helper cell activity. Immunology. 2010;131:488-500 pubmed publisher
|
| Wu Y, Lin C, Cheng K, Lin C, Wang Y, Lin I, et al. Increased programmed death-ligand-1 expression in human gastric epithelial cells in Helicobacter pylori infection. Clin Exp Immunol. 2010;161:551-9 pubmed publisher
|
| Lechner M, Liebertz D, Epstein A. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. J Immunol. 2010;185:2273-84 pubmed publisher
|
| Hislop A, Palendira U, Leese A, Arkwright P, Rohrlich P, Tangye S, et al. Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets. Blood. 2010;116:3249-57 pubmed publisher
|
| Alvarez I, Pasquinelli V, Jurado J, Abbate E, Musella R, de la Barrera S, et al. Role played by the programmed death-1-programmed death ligand pathway during innate immunity against Mycobacterium tuberculosis. J Infect Dis. 2010;202:524-32 pubmed publisher
|
| Brown M, Rondon E, Rajesh D, Mack A, Lewis R, Feng X, et al. Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes. PLoS ONE. 2010;5:e11373 pubmed publisher
|
| Knight A, Madrigal A, Grace S, Sivakumaran J, Kottaridis P, Mackinnon S, et al. The role of V?2-negative ?? T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation. Blood. 2010;116:2164-72 pubmed publisher
|
| Lee J, Yoon S, Kim H, Kim S, Sohn H, Oh S, et al. Direct and indirect antitumor effects by human peripheral blood lymphocytes expressing both chimeric immune receptor and interleukin-2 in ovarian cancer xenograft model. Cancer Gene Ther. 2010;17:742-50 pubmed publisher
|
| Ladd M, Sharma A, Huang Q, Wang A, Xu L, Genowati I, et al. Natural killer T cells constitutively expressing the interleukin-2 receptor ? chain early in life are primed to respond to lower antigenic stimulation. Immunology. 2010;131:289-99 pubmed publisher
|
| Richardt Pargmann D, Wechsler M, Krieg A, Vollmer J, Jurk M. Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment. Immunobiology. 2011;216:12-23 pubmed publisher
|
| Webb J, Wick D, Nielsen J, Tran E, Milne K, McMurtrie E, et al. Profound elevation of CD8+ T cells expressing the intraepithelial lymphocyte marker CD103 (alphaE/beta7 Integrin) in high-grade serous ovarian cancer. Gynecol Oncol. 2010;118:228-36 pubmed publisher
|
| Guo P, Du M, Wu H, Lin Y, Jin L, Li D. Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans. Blood. 2010;116:2061-9 pubmed publisher
|
| Xu Y, Gao Y, Yang J, Guo W. A defect of CD4+CD25+ regulatory T cells in inducing interleukin-10 production from CD4+ T cells under CD46 costimulation in asthma patients. J Asthma. 2010;47:367-73 pubmed publisher
|
| Kanari H, Kagami S, Kashiwakuma D, Oya Y, Furuta S, Ikeda K, et al. Role of Th2 cells in IgG4-related lacrimal gland enlargement. Int Arch Allergy Immunol. 2010;152 Suppl 1:47-53 pubmed publisher
|
| Zuo J, Church J, Belzer M, Kitchen C, Ank B, Schmid I, et al. Short communication: enhanced CD8+ T cell apoptosis in HIV-infected adolescents with virologic failure on protease inhibitor-based therapy. AIDS Res Hum Retroviruses. 2010;26:681-4 pubmed publisher
|
| Pan W, Zhu S, Yuan M, Cui H, Wang L, Luo X, et al. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol. 2010;184:6773-81 pubmed publisher
|
| Fourcade J, Sun Z, Kudela P, Janjic B, Kirkwood J, El Hafnawy T, et al. Human tumor antigen-specific helper and regulatory T cells share common epitope specificity but exhibit distinct T cell repertoire. J Immunol. 2010;184:6709-18 pubmed publisher
|
| Cao T, Wenzel S, Faubion W, Harriman G, Li L. Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion. Clin Immunol. 2010;136:329-37 pubmed publisher
|
| Martinet L, Jean C, Dietrich G, Fournie J, Poupot R. PGE2 inhibits natural killer and gamma delta T cell cytotoxicity triggered by NKR and TCR through a cAMP-mediated PKA type I-dependent signaling. Biochem Pharmacol. 2010;80:838-45 pubmed publisher
|
| Zavialov A, Gracia E, Glaichenhaus N, Franco R, Zavialov A, Lauvau G. Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages. J Leukoc Biol. 2010;88:279-90 pubmed publisher
|
| Tang H, Zhong Y, Zhu Y, Zhao F, Cui X, Wang Z. Low responder T cell susceptibility to the suppressive function of regulatory T cells in patients with dilated cardiomyopathy. Heart. 2010;96:765-71 pubmed publisher
|
| Stevens C, Simeone A, John S, Ahmed Z, Lucherini O, Baldari C, et al. T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation. Biochem J. 2010;428:429-37 pubmed publisher
|
| Tokunaga A, Tsukimoto M, Harada H, Moriyama Y, Kojima S. Involvement of SLC17A9-dependent vesicular exocytosis in the mechanism of ATP release during T cell activation. J Biol Chem. 2010;285:17406-16 pubmed publisher
|
| Sawasdikosol S. Detecting tyrosine-phosphorylated proteins by Western blot analysis. Curr Protoc Immunol. 2010;Chapter 11:Unit 11.3.1-11 pubmed publisher
|
| Vermijlen D, Brouwer M, Donner C, Liesnard C, Tackoen M, Van Rysselberge M, et al. Human cytomegalovirus elicits fetal gammadelta T cell responses in utero. J Exp Med. 2010;207:807-21 pubmed publisher
|
| Matthews K, Lim Z, Pearce L, Pagliuca A, Alejandro Madrigal J, Mufti G, et al. Rapid recovery of lymphocyte subsets is not associated with protection from relapse of myelodysplastic syndromes and acute myeloid leukaemia after haematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab. Br J Haematol. 2010;149:879-89 pubmed publisher
|
| Liu X, Shin N, Koblish H, Yang G, Wang Q, Wang K, et al. Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. Blood. 2010;115:3520-30 pubmed publisher
|
| Markley J, Sadelain M. IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell-mediated rejection of systemic lymphoma in immunodeficient mice. Blood. 2010;115:3508-19 pubmed publisher
|
| Swainson L, Mold J, Bajpai U, McCune J. Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1. J Immunol. 2010;184:3639-47 pubmed publisher
|
| Thornton A, Korty P, Tran D, Wohlfert E, Murray P, Belkaid Y, et al. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol. 2010;184:3433-41 pubmed publisher
|
| Wang Y, Radfar S, Khong H. Activated CD4+ T cells enhance radiation effect through the cooperation of interferon-gamma and TNF-alpha. BMC Cancer. 2010;10:60 pubmed publisher
|
| Srivastava R, Burbach B, Shimizu Y. NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein. J Biol Chem. 2010;285:11100-5 pubmed publisher
|
| Bouchier Hayes L, McBride S, van Geelen C, Nance S, Lewis L, Pinkoski M, et al. Fas ligand gene expression is directly regulated by stress-inducible heat shock transcription factor-1. Cell Death Differ. 2010;17:1034-46 pubmed publisher
|
| Owen D, Rentero C, Rossy J, Magenau A, Williamson D, Rodriguez M, et al. PALM imaging and cluster analysis of protein heterogeneity at the cell surface. J Biophotonics. 2010;3:446-54 pubmed publisher
|
| Fei F, Yu Y, Schmitt A, Rojewski M, Chen B, Greiner J, et al. Effects of nilotinib on regulatory T cells: the dose matters. Mol Cancer. 2010;9:22 pubmed publisher
|
| Hoe E, McKay F, Schibeci S, Gandhi K, Heard R, Stewart G, et al. Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells. J Immunol. 2010;184:2512-7 pubmed publisher
|
| Wei J, Barr J, Kong L, Wang Y, Wu A, Sharma A, et al. Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway. Mol Cancer Ther. 2010;9:67-78 pubmed publisher
|
| Godin Ethier J, Pelletier S, Hanafi L, Gannon P, Forget M, Routy J, et al. Human activated T lymphocytes modulate IDO expression in tumors through Th1/Th2 balance. J Immunol. 2009;183:7752-60 pubmed publisher
|
| Benwell R, Lee D. Essential and synergistic roles of IL1 and IL6 in human Th17 differentiation directed by TLR ligand-activated dendritic cells. Clin Immunol. 2010;134:178-87 pubmed publisher
|
| Radfar S, Wang Y, Khong H. Activated CD4+ T cells dramatically enhance chemotherapeutic tumor responses in vitro and in vivo. J Immunol. 2009;183:6800-7 pubmed publisher
|
| Vazquez B, Laguna T, Carabana J, Krangel M, Lauzurica P. CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements. J Immunol. 2009;183:6513-21 pubmed publisher
|
| Heap G, Yang J, Downes K, Healy B, Hunt K, Bockett N, et al. Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing. Hum Mol Genet. 2010;19:122-34 pubmed publisher
|
| Kebir H, Ifergan I, Alvarez J, Bernard M, Poirier J, Arbour N, et al. Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis. Ann Neurol. 2009;66:390-402 pubmed publisher
|
| Lehmann R, Meyer J, Schuemann M, Krause E, Freund C. A novel S3S-TAP-tag for the isolation of T-cell interaction partners of adhesion and degranulation promoting adaptor protein. Proteomics. 2009;9:5288-95 pubmed publisher
|
| Stahl H, Fauti T, Ullrich N, Bopp T, Kubach J, Rust W, et al. miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression. PLoS ONE. 2009;4:e7158 pubmed publisher
|
| Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya acov A, Hemed N, et al. Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells. J Clin Immunol. 2010;30:167-77 pubmed publisher
|
| Sillaber C, Herrmann H, Bennett K, Rix U, Baumgartner C, Bohm A, et al. Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily. Eur J Clin Invest. 2009;39:1098-109 pubmed publisher
|
| Gur Wahnon D, Borovsky Z, Liebergall M, Rachmilewitz J. The induction of APC with a distinct tolerogenic phenotype via contact-dependent STAT3 activation. PLoS ONE. 2009;4:e6846 pubmed publisher
|
| Chen H, Li C, Grigorian A, Tian W, Demetriou M. T cell receptor signaling co-regulates multiple Golgi genes to enhance N-glycan branching. J Biol Chem. 2009;284:32454-61 pubmed publisher
|
| Keeren K, Friedrich M, Gebuhr I, Philipp S, Sabat R, Sterry W, et al. Expression of tolerance associated gene-1, a mitochondrial protein inhibiting T cell activation, can be used to predict response to immune modulating therapies. J Immunol. 2009;183:4077-87 pubmed publisher
|
| Andersen M, Sørensen R, Brimnes M, Svane I, Becker J, thor Straten P. Identification of heme oxygenase-1-specific regulatory CD8+ T cells in cancer patients. J Clin Invest. 2009;119:2245-56 pubmed
|
| Bollyky P, Falk B, Long S, Preisinger A, Braun K, Wu R, et al. CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta. J Immunol. 2009;183:2232-41 pubmed publisher
|
| Sommershof A, Aichinger H, Engler H, Adenauer H, Catani C, Boneberg E, et al. Substantial reduction of naïve and regulatory T cells following traumatic stress. Brain Behav Immun. 2009;23:1117-24 pubmed publisher
|
| Nguyen V, Cao L, Lin J, Hung N, Ritz A, Yu K, et al. A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Mol Cell Proteomics. 2009;8:2418-31 pubmed publisher
|
| Li R, Wei F, Yu J, Li H, Ren X, Hao X. IDO inhibits T-cell function through suppressing Vav1 expression and activation. Cancer Biol Ther. 2009;8:1402-8 pubmed
|
| Gorska M, Liang Q, Karim Z, Alam R. Uncoordinated 119 protein controls trafficking of Lck via the Rab11 endosome and is critical for immunological synapse formation. J Immunol. 2009;183:1675-84 pubmed publisher
|
| Mailer R, Falk K, Rotzschke O. Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity. PLoS ONE. 2009;4:e6104 pubmed publisher
|
| Matthews K, Lim Z, Afzali B, Pearce L, Abdallah A, Kordasti S, et al. Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab. Haematologica. 2009;94:956-66 pubmed publisher
|
| Shulman Z, Alon R. Chapter 14. Real-time in vitro assays for studying the role of chemokines in lymphocyte transendothelial migration under physiologic flow conditions. Methods Enzymol. 2009;461:311-32 pubmed publisher
|
| Correia D, d Orey F, Cardoso B, Lança T, Grosso A, deBarros A, et al. Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. PLoS ONE. 2009;4:e5657 pubmed publisher
|
| MacMillan H, Lee T, Issekutz A. Intravenous immunoglobulin G-mediated inhibition of T-cell proliferation reflects an endogenous mechanism by which IgG modulates T-cell activation. Clin Immunol. 2009;132:222-33 pubmed publisher
|
| Brandt C, Pavlovic V, Radbruch A, Worm M, Baumgrass R. Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis. Allergy. 2009;64:1588-96 pubmed publisher
|
| Cao T, Soto A, Zhou W, Wang W, Eck S, Walker M, et al. Ex vivo expanded human CD4+CD25+Foxp3+ regulatory T cells prevent lethal xenogenic graft versus host disease (GVHD). Cell Immunol. 2009;258:65-71 pubmed publisher
|
| Takahashi N, Matsumoto K, Saito H, Nanki T, Miyasaka N, Kobata T, et al. Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients. J Immunol. 2009;182:5515-27 pubmed publisher
|
| Ilani T, Vasiliver Shamis G, Vardhana S, Bretscher A, Dustin M. T cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nat Immunol. 2009;10:531-9 pubmed publisher
|
| Toulon A, Breton L, Taylor K, Tenenhaus M, Bhavsar D, Lanigan C, et al. A role for human skin-resident T cells in wound healing. J Exp Med. 2009;206:743-50 pubmed publisher
|
| Wang X, Barnes P, Dobos Elder K, Townsend J, Chung Y, Shams H, et al. ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells. J Immunol. 2009;182:3668-77 pubmed publisher
|
| Alam M, Kurtz C, Wilson J, Burnette B, Wiznerowicz E, Ross W, et al. A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence. Mucosal Immunol. 2009;2:232-42 pubmed publisher
|
| Hirsch A, Rivet C, Zhang B, Kemp M, Lu H. Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation. Lab Chip. 2009;9:536-44 pubmed publisher
|
| Takamatsu H, Espinoza J, Lu X, Qi Z, Okawa K, Nakao S. Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma. J Immunol. 2009;182:703-10 pubmed
|
| Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger E, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol. 2009;182:259-73 pubmed
|
| Yoon S, Lee J, Cho H, Kim E, Kim H, Park M, et al. Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model. Cancer Gene Ther. 2009;16:489-97 pubmed publisher
|
| de Jager W, Prakken B, Rijkers G. Cytokine multiplex immunoassay: methodology and (clinical) applications. Methods Mol Biol. 2009;514:119-33 pubmed publisher
|
| Bollinger T, Bollinger A, Skrum L, Dimitrov S, Lange T, Solbach W. Sleep-dependent activity of T cells and regulatory T cells. Clin Exp Immunol. 2009;155:231-8 pubmed publisher
|
| Yang K, Wen J, Liu X, Kijlstra A, Chen L, Chi W, et al. Inhibitory effect of rapamycin and dexamethasone on production of IL-17 and IFN-gamma in Vogt-Koyanagi-Harada patients. Br J Ophthalmol. 2009;93:249-53 pubmed publisher
|
| Fei F, Yu Y, Schmitt A, Rojewski M, Chen B, Götz M, et al. Dasatinib inhibits the proliferation and function of CD4+CD25+ regulatory T cells. Br J Haematol. 2009;144:195-205 pubmed publisher
|
| Navabi H, Jasani B, Reece A, Clayton A, Tabi Z, Donninger C, et al. A clinical grade poly I:C-analogue (Ampligen) promotes optimal DC maturation and Th1-type T cell responses of healthy donors and cancer patients in vitro. Vaccine. 2009;27:107-15 pubmed publisher
|
| Manzo A, Vitolo B, Humby F, Caporali R, Jarrossay D, Dell accio F, et al. Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint. Arthritis Rheum. 2008;58:3377-87 pubmed publisher
|
| Puhar A, Dal Molin F, Horvath S, Ladant D, Ladants D, Montecucco C. Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases. PLoS ONE. 2008;3:e3564 pubmed publisher
|
| Colucci A, Giunti R, Senesi S, Bygrave F, Benedetti A, Gamberucci A. Effect of nifedipine on capacitive calcium entry in Jurkat T lymphocytes. Arch Biochem Biophys. 2009;481:80-5 pubmed publisher
|
| Sadri N, Schneider R. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol. 2009;129:657-70 pubmed publisher
|
| Gulen D, Abe F, Maas S, Reed E, Cowan K, Pirruccello S, et al. Closing the manufacturing process of dendritic cell vaccines transduced with adenovirus vectors. Int Immunopharmacol. 2008;8:1728-36 pubmed publisher
|
| Zappasodi R, Di Nicola M, Carlo Stella C, Mortarini R, Molla A, Vegetti C, et al. The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the induction of ex vivo expansion of functional human antitumor T cells. Haematologica. 2008;93:1523-34 pubmed publisher
|
| Nograles K, Zaba L, Guttman Yassky E, Fuentes Duculan J, Suárez Fariñas M, Cardinale I, et al. Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br J Dermatol. 2008;159:1092-102 pubmed publisher
|
| Boasso A, Hardy A, Landay A, Martinson J, Anderson S, Dolan M, et al. PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes. Clin Immunol. 2008;129:132-44 pubmed publisher
|
| Fan C, Huang C, Chiu W, Lai C, Liou G, Li H, et al. Production of multivalent protein binders using a self-trimerizing collagen-like peptide scaffold. FASEB J. 2008;22:3795-804 pubmed publisher
|
| Amsalem H, Gaiger A, Mizrahi S, Yagel S, Rachmilewitz J. Characterization of a lymphocyte subset displaying a unique regulatory activity in human decidua. Int Immunol. 2008;20:1147-54 pubmed publisher
|
| Okumura A, Ishikawa T, Sato S, Yamauchi T, Oshima H, Ohashi T, et al. Deficiency of forkhead box P3 and cytotoxic T-lymphocyte-associated antigen-4 gene expressions and impaired suppressor function of CD4(+)CD25(+) T cells in patients with autoimmune hepatitis. Hepatol Res. 2008;38:896-903 pubmed publisher
|
| Fei F, Yu Y, Schmitt A, Rojewski M, Chen B, Greiner J, et al. Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukemia antigens. Exp Hematol. 2008;36:1297-308 pubmed publisher
|
| Matsushita Y, Ohya S, Itoda H, Kimura T, Suzuki Y, Yamamura H, et al. Molecular mechanisms for Kv1.3 potassium channel current inhibition by CD3/CD28 stimulation in Jurkat T cells. Biochem Biophys Res Commun. 2008;374:152-7 pubmed publisher
|
| Klucar P, Barnes P, Kong Y, Samten B, Tvinnereim A, Spallek R, et al. Characterization of effector functions of human peptide-specific CD4+ T-cell clones for an intracellular pathogen. Hum Immunol. 2008;69:475-83 pubmed publisher
|
| Miyazaki Y, Iwabuchi K, Kikuchi S, Fukazawa T, Niino M, Hirotani M, et al. Expansion of CD4+CD28- T cells producing high levels of interferon-{gamma} in peripheral blood of patients with multiple sclerosis. Mult Scler. 2008;14:1044-55 pubmed publisher
|
| Huarte E, Cubillos Ruiz J, Nesbeth Y, Scarlett U, Martinez D, Engle X, et al. PILAR is a novel modulator of human T-cell expansion. Blood. 2008;112:1259-68 pubmed publisher
|
| Manes T, Pober J. Antigen presentation by human microvascular endothelial cells triggers ICAM-1-dependent transendothelial protrusion by, and fractalkine-dependent transendothelial migration of, effector memory CD4+ T cells. J Immunol. 2008;180:8386-92 pubmed
|
| Turul T, Tezcan I, Artac H, de Bruin Versteeg S, Barendregt B, Reisli I, et al. Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency. Eur J Pediatr. 2009;168:87-93 pubmed publisher
|
| Arimura Y, Vang T, Tautz L, Williams S, Mustelin T. TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses. Mol Immunol. 2008;45:3074-84 pubmed publisher
|
| D Acquisto F, Paschalidis N, Raza K, Buckley C, Flower R, Perretti M. Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells. Rheumatology (Oxford). 2008;47:636-9 pubmed publisher
|
| Gong W, Ji M, Cao Z, Wang L, Qian Y, Hu M, et al. Establishment and characterization of a cell based artificial antigen-presenting cell for expansion and activation of CD8+ T cells ex vivo. Cell Mol Immunol. 2008;5:47-53 pubmed publisher
|
| Yan B, Ye S, Chen G, Kuang M, Shen N, Chen S. Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells. Arthritis Rheum. 2008;58:801-12 pubmed publisher
|
| Hilchey S, Bernstein S. Use of CFSE to monitor ex vivo regulatory T-cell suppression of CD4+ and CD8+ T-cell proliferation within unseparated mononuclear cells from malignant and non-malignant human lymph node biopsies. Immunol Invest. 2007;36:629-48 pubmed
|
| Coury F, Annels N, Rivollier A, Olsson S, Santoro A, Speziani C, et al. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. Nat Med. 2008;14:81-7 pubmed
|
| Ifergan I, Kebir H, Bernard M, Wosik K, Dodelet Devillers A, Cayrol R, et al. The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. Brain. 2008;131:785-99 pubmed
|
| Jeong H, Lee Y, Seo S, Lee S, Park S, Lee J, et al. Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection. J Leukoc Biol. 2008;83:755-64 pubmed
|
| Yu X, Sun J, He Y, Guo X, Liu S, Zhou B, et al. Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. Proc Natl Acad Sci U S A. 2007;104:19767-72 pubmed
|
| Ramaswamy M, Dumont C, Cruz A, Muppidi J, Gomez T, Billadeau D, et al. Cutting edge: Rac GTPases sensitize activated T cells to die via Fas. J Immunol. 2007;179:6384-8 pubmed
|
| Chen I, Chen H, Demetriou M. Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. J Biol Chem. 2007;282:35361-72 pubmed
|
| Herling M, Patel K, Teitell M, Konopleva M, Ravandi F, Kobayashi R, et al. High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia. Blood. 2008;111:328-37 pubmed
|
| Waggoner S, Hall C, Hahn Y. HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production. J Leukoc Biol. 2007;82:1407-19 pubmed
|
| Chin L, Chu C, Chen H, Hsu S, Weng B, Chu C. Site-directed in vitro immunization leads to a complete human monoclonal IgG4 lambda that binds specifically to the CDR2 region of CTLA-4 (CD152) without interfering the engagement of natural ligands. BMC Biotechnol. 2007;7:51 pubmed
|
| Kim J, Kim H, Hurt E, Chen X, Howard O, Farrar W. Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells. Biochem Biophys Res Commun. 2007;362:44-50 pubmed publisher
|
| Pascal V, Yamada E, Martin M, Alter G, Altfeld M, Metcalf J, et al. Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection. J Immunol. 2007;179:1625-33 pubmed
|
| Kondo N, Ishii Y, Kwon Y, Tanito M, Sakakura Nishiyama J, Mochizuki M, et al. Lipid raft-mediated uptake of cysteine-modified thioredoxin-1: apoptosis enhancement by inhibiting the endogenous thioredoxin-1. Antioxid Redox Signal. 2007;9:1439-48 pubmed
|
| Kesti T, Ruppelt A, Wang J, Liss M, Wagner R, Tasken K, et al. Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon. J Immunol. 2007;179:878-85 pubmed
|
| Zeng H, Di L, Fu G, Chen Y, Gao X, Xu L, et al. Phosphorylation of Bcl10 negatively regulates T-cell receptor-mediated NF-kappaB activation. Mol Cell Biol. 2007;27:5235-45 pubmed
|
| Binné L, Scott M, Rennert P. Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals. J Immunol. 2007;178:4342-50 pubmed
|
| Hilchey S, De A, Rimsza L, Bankert R, Bernstein S. Follicular lymphoma intratumoral CD4+CD25+GITR+ regulatory T cells potently suppress CD3/CD28-costimulated autologous and allogeneic CD8+CD25- and CD4+CD25- T cells. J Immunol. 2007;178:4051-61 pubmed
|
| Boulland M, Marquet J, Molinier Frenkel V, Moller P, Guiter C, Lasoudris F, et al. Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation. Blood. 2007;110:220-7 pubmed
|
| Manes T, Shiao S, Dengler T, Pober J. TCR signaling antagonizes rapid IP-10-mediated transendothelial migration of effector memory CD4+ T cells. J Immunol. 2007;178:3237-43 pubmed
|
| Ahn J, Krishnadas D, Agrawal B. Dendritic cells partially abrogate the regulatory activity of CD4+CD25+ T cells present in the human peripheral blood. Int Immunol. 2007;19:227-37 pubmed
|
| Baba M, Yong Ma B, Nonaka M, Matsuishi Y, Hirano M, Nakamura N, et al. Glycosylation-dependent interaction of Jacalin with CD45 induces T lymphocyte activation and Th1/Th2 cytokine secretion. J Leukoc Biol. 2007;81:1002-11 pubmed
|
| Konno A, Kirby M, Anderson S, Schwartzberg P, Candotti F. The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP). Int Immunol. 2007;19:185-92 pubmed
|
| Caudy A, Reddy S, Chatila T, Atkinson J, Verbsky J. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes. J Allergy Clin Immunol. 2007;119:482-7 pubmed
|
| Ranjbaran H, Sokol S, Gallo A, Eid R, Iakimov A, D Alessio A, et al. An inflammatory pathway of IFN-gamma production in coronary atherosclerosis. J Immunol. 2007;178:592-604 pubmed
|
| O Connor G, Guinan K, Cunningham R, Middleton D, Parham P, Gardiner C. Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells. J Immunol. 2007;178:235-41 pubmed
|
| Boasso A, Herbeuval J, Hardy A, Anderson S, Dolan M, Fuchs D, et al. HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood. 2007;109:3351-9 pubmed
|
| Gasser O, Schmid T, Zenhaeusern G, Hess C. Cyclooxygenase regulates cell surface expression of CXCR3/1-storing granules in human CD4+ T cells. J Immunol. 2006;177:8806-12 pubmed
|
| Zhu L, Ji F, Wang Y, Zhang Y, Liu Q, Zhang J, et al. Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J Immunol. 2006;177:8226-33 pubmed
|
| Simonson W, Franco S, Huttenlocher A. Talin1 regulates TCR-mediated LFA-1 function. J Immunol. 2006;177:7707-14 pubmed
|
| Garg R, Juncadella I, Ramamoorthi N, Ashish -, Ananthanarayanan S, Thomas V, et al. Cutting edge: CD4 is the receptor for the tick saliva immunosuppressor, Salp15. J Immunol. 2006;177:6579-83 pubmed
|
| Wu M, Buchanan J, Luik R, Lewis R. Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J Cell Biol. 2006;174:803-13 pubmed
|
| Derdak S, Kueng H, Leb V, Neunkirchner A, Schmetterer K, Bielek E, et al. Direct stimulation of T lymphocytes by immunosomes: virus-like particles decorated with T cell receptor/CD3 ligands plus costimulatory molecules. Proc Natl Acad Sci U S A. 2006;103:13144-9 pubmed
|
| Muhlbauer M, Fleck M, Schutz C, Weiss T, Froh M, Blank C, et al. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis. J Hepatol. 2006;45:520-8 pubmed
|
| Fraser D, Bohlson S, Jasinskiene N, Rawal N, Palmarini G, Ruiz S, et al. C1q and MBL, components of the innate immune system, influence monocyte cytokine expression. J Leukoc Biol. 2006;80:107-16 pubmed
|
| Loza M, Foster S, Peters S, Penn R. Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells. Blood. 2006;107:2052-60 pubmed
|
| Raffeiner B, Dejaco C, Duftner C, Kullich W, Goldberger C, Vega S, et al. Between adaptive and innate immunity: TLR4-mediated perforin production by CD28null T-helper cells in ankylosing spondylitis. Arthritis Res Ther. 2005;7:R1412-20 pubmed
|
| Ito T, Wang Y, Duramad O, Hori T, Delespesse G, Watanabe N, et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med. 2005;202:1213-23 pubmed
|
| Gasser O, Missiou A, Eken C, Hess C. Human CD8+ T cells store CXCR1 in a distinct intracellular compartment and up-regulate it rapidly to the cell surface upon activation. Blood. 2005;106:3718-24 pubmed
|
| Kroner A, Mehling M, Hemmer B, Rieckmann P, Toyka K, Maurer M, et al. A PD-1 polymorphism is associated with disease progression in multiple sclerosis. Ann Neurol. 2005;58:50-7 pubmed
|
| Serrano C, Graham L, DeBell K, Rawat R, Veri M, Bonvini E, et al. A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling. J Immunol. 2005;174:6233-7 pubmed
|
| Gotter J, Brors B, Hergenhahn M, Kyewski B. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J Exp Med. 2004;199:155-66 pubmed
|
| Gilliet M, Soumelis V, Watanabe N, Hanabuchi S, Antonenko S, de Waal Malefyt R, et al. Human dendritic cells activated by TSLP and CD40L induce proallergic cytotoxic T cells. J Exp Med. 2003;197:1059-63 pubmed
|
| Gilliet M, Liu Y. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J Exp Med. 2002;195:695-704 pubmed
|