Published Application/Species/Sample/Dilution | Reference |
---|
- blocking or activating experiments; human; 0.25 ug/ml; loading ...; fig 5d
| Pinkert J, Boehm H, Trautwein M, Doecke W, Wessel F, Ge Y, et al. T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction. Oncoimmunology. 2022;11:2008110 pubmed publisher
|
- blocking or activating experiments; human; 2 ug/ml; loading ...; fig 4b
| Thakkar D, Paliwal S, Dharmadhikari B, Guan S, Liu L, Kar S, et al. Rationally targeted anti-VISTA antibody that blockades the C-C' loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner. J Immunother Cancer. 2022;10: pubmed publisher
|
- flow cytometry; human; loading ...; fig 1a
| Banki Z, Krabbendam L, Klaver D, Leng T, Kruis S, Mehta H, et al. Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism. Immunol Cell Biol. 2019;97:538-551 pubmed publisher
|
| Lin M, Bhakdi S, Tan D, Lee J, Tai D, Pavesi A, et al. Lytic efficiency of immunosuppressive drug-resistant armoured T cells against circulating HBV-related HCC in whole blood. Immunother Adv. 2023;3:ltad015 pubmed publisher
|
| Jaeger H, Davis D, Nair A, Shrestha P, Stream A, Yaparla A, et al. Mechanism and therapeutic implications of pomalidomide-induced immune surface marker upregulation in EBV-positive lymphomas. Sci Rep. 2023;13:11596 pubmed publisher
|
| Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, et al. HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway. J Exp Clin Cancer Res. 2023;42:38 pubmed publisher
|
| Kong F, Ye Q, Xiong Y. Comprehensive analysis of prognosis and immune function of CD70-CD27 signaling axis in pan-cancer. Funct Integr Genomics. 2023;23:48 pubmed publisher
|
| Rode A, Buus T, Mraz V, Al Jaberi F, Lopez D, Ford S, et al. Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor. Cells. 2022;11: pubmed publisher
|
| Banerjee A, Li D, Guo Y, Mei Z, Lau C, Chen K, et al. A reengineered common chain cytokine augments CD8+ T cell-dependent immunotherapy. JCI Insight. 2022;7: pubmed publisher
|
| Jensen L, Hoh T, Williamson D, Griffi xe9 J, Sage D, Rubin Delanchy P, et al. Correction of multiple-blinking artifacts in photoactivated localization microscopy. Nat Methods. 2022;19:594-602 pubmed publisher
|
| Saveljeva S, Sewell G, Ramshorn K, Cader M, West J, Clare S, et al. A purine metabolic checkpoint that prevents autoimmunity and autoinflammation. Cell Metab. 2022;34:106-124.e10 pubmed publisher
|
| Siegemund M, Oak P, Hansbauer E, Allersdorfer A, Utschick K, Winter A, et al. Pharmacokinetic Engineering of OX40-Blocking Anticalin Proteins Using Monomeric Plasma Half-Life Extension Domains. Front Pharmacol. 2021;12:759337 pubmed publisher
|
| Geuijen C, Tacken P, Wang L, Klooster R, Van Loo P, Zhou J, et al. A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade. Nat Commun. 2021;12:4445 pubmed publisher
|
| Puertas M, Bayón Gil Á, Garcia Guerrero M, Salgado M, Urrea V, Morón López S, et al. VIP-SPOT: an Innovative Assay To Quantify the Productive HIV-1 Reservoir in the Monitoring of Cure Strategies. MBio. 2021;12:e0056021 pubmed publisher
|
| Xun X, Zhang C, Wang S, Hu S, Xiang X, Cheng Q, et al. Cyclooxygenase-2 expressed hepatocellular carcinoma induces cytotoxic T lymphocytes exhaustion through M2 macrophage polarization. Am J Transl Res. 2021;13:4360-4375 pubmed
|
| Szanto C, Cornel A, Tamminga S, Delemarre E, de Koning C, van den Beemt D, et al. Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma. Cancers (Basel). 2021;13: pubmed publisher
|
| Feldman T, Bercovich A, Moskovitz Y, Chapal Ilani N, Mitchell A, Medeiros J, et al. Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining. Nat Commun. 2021;12:2455 pubmed publisher
|
| Rubio Perez C, Planas Rigol E, Trincado J, Bonfill Teixidor E, Arias A, Marchese D, et al. Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment. Nat Commun. 2021;12:1503 pubmed publisher
|
| Zehravi M, Wahid M, Ashraf J. Episomal reprogramming of Duchenne muscular dystrophy patients derived CD3+ T cells towards induced pluripotent stem cells. Pak J Med Sci. 2021;37:432-438 pubmed publisher
|
| Bost P, De Sanctis F, Cane S, Ugel S, Donadello K, Castellucci M, et al. Deciphering the state of immune silence in fatal COVID-19 patients. Nat Commun. 2021;12:1428 pubmed publisher
|
| Li H, Kuang X, Liang L, Ye Y, Zhang Y, Li J, et al. The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD-L1. Adv Sci (Weinh). 2021;8:2001596 pubmed publisher
|
| Liu B, Xie Y, Mei X, Sun Y, Shi W, Wu Z. Reciprocal regulation of interleukin-17A and interleukin-22 secretion through aryl hydrocarbon receptor activation in CD4+ T cells of patients with vitiligo. Exp Ther Med. 2021;21:158 pubmed publisher
|
| Wang T, Zhou Q, Shang Y. Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma. J Innate Immun. 2021;13:38-48 pubmed publisher
|
| Podojil J, Ifergan I, Chiang M, Meeks J, Miller S. Methodology for in vitro Assessment of Human T Cell Activation and Blockade. Bio Protoc. 2020;10:e3644 pubmed publisher
|
| Lund M, Howard C, Thurecht K, Campbell D, Mahler S, Walsh B. A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer. 2020;20:1214 pubmed publisher
|
| Renavikar P, Sinha S, Brate A, Borcherding N, Crawford M, Steward Tharp S, et al. IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation. Front Immunol. 2020;11:568630 pubmed publisher
|
| Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai C, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. 2020;183:1479-1495.e20 pubmed publisher
|
| Ferretti A, Kula T, Wang Y, Nguyen D, Weinheimer A, Dunlap G, et al. Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein. Immunity. 2020;53:1095-1107.e3 pubmed publisher
|
| Yang J, Zhang J, Lu R, Tan Y, Du G, Zhou G. T cell-derived exosomes induced macrophage inflammatory protein-1α/β drive the trafficking of CD8+ T cells in oral lichen planus. J Cell Mol Med. 2020;24:14086-14098 pubmed publisher
|
| Biemann R, Roomp K, Noor F, Krishnan S, Li Z, Shahzad K, et al. Gene expression profile of CD14+ blood monocytes following lifestyle-induced weight loss in individuals with metabolic syndrome. Sci Rep. 2020;10:17855 pubmed publisher
|
| Lee J, Sheen J, Lim O, Lee Y, Ryu J, Shin D, et al. Abrogation of HLA surface expression using CRISPR/Cas9 genome editing: a step toward universal T cell therapy. Sci Rep. 2020;10:17753 pubmed publisher
|
| Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, et al. Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1. Genome Med. 2020;12:83 pubmed publisher
|
| Sadik A, Somarribas Patterson L, Oztürk S, Mohapatra S, Panitz V, Secker P, et al. IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression. Cell. 2020;182:1252-1270.e34 pubmed publisher
|
| Kuehn H, Bernasconi A, Niemela J, Almejún M, Gallego W, Goel S, et al. A Nonsense N -Terminus NFKB2 Mutation Leading to Haploinsufficiency in a Patient with a Predominantly Antibody Deficiency. J Clin Immunol. 2020;40:1093-1101 pubmed publisher
|
| Boshuizen J, Vredevoogd D, Krijgsman O, Ligtenberg M, Blankenstein S, de Bruijn B, et al. Reversal of pre-existing NGFR-driven tumor and immune therapy resistance. Nat Commun. 2020;11:3946 pubmed publisher
|
| Crawford M, Sinha S, Renavikar P, Borcherding N, Karandikar N. CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression. Proc Natl Acad Sci U S A. 2020;117:19408-19414 pubmed publisher
|
| Ferrara M, Chialli G, Ferreira L, Ruggieri E, Careccia G, Preti A, et al. Oxidation of HMGB1 Is a Dynamically Regulated Process in Physiological and Pathological Conditions. Front Immunol. 2020;11:1122 pubmed publisher
|
| Sahin M, Sahin E. Prostaglandin E2 Reverses the Effects of DNA Methyltransferase Inhibitor and TGFB1 on the Conversion of Naive T Cells to iTregs. Transfus Med Hemother. 2020;47:244-253 pubmed publisher
|
| Wragg K, Tan H, Kristensen A, Nguyen Robertson C, Kelleher A, Parsons M, et al. High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile. Cell Rep. 2020;31:107773 pubmed publisher
|
| Rollins M, Spartz E, Stromnes I. T Cell Receptor Engineered Lymphocytes for Cancer Therapy. Curr Protoc Immunol. 2020;129:e97 pubmed publisher
|
| Hu J, Lei B, Wen D, Ma B, Zhang T, Lu Z, et al. IL-2 enhanced MHC class I expression in papillary thyroid cancer with Hashimoto's thyroiditis overcomes immune escape in vitro. J Cancer. 2020;11:4250-4260 pubmed publisher
|
| Lu Z, Hu J, Liu W, Wen D, Wei W, Wang Y, et al. IL-10 Restores MHC Class I Expression and Interferes With Immunity in Papillary Thyroid Cancer With Hashimoto Thyroiditis. Endocrinology. 2020;161: pubmed publisher
|
| Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, et al. JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Cell Death Differ. 2020;: pubmed publisher
|
| Ma Y, Yang Q, Fan M, Zhang L, Gu Y, Jia W, et al. Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation. Cell Prolif. 2020;53:e12802 pubmed publisher
|
| Salazar Y, Zheng X, Brunn D, Raifer H, Picard F, Zhang Y, et al. Microenvironmental Th9- and Th17- lymphocytes induce metastatic spreading in lung cancer. J Clin Invest. 2020;: pubmed publisher
|
| Ko J, Kim H, Jeong H, Lee H, Oh J. Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis. Cell Rep. 2020;30:3806-3820.e6 pubmed publisher
|
| Li W, Aryal M, Shu S, Smithgall T. HIV-1 Nef dimers short-circuit immune receptor signaling by activating Tec-family kinases at the host cell membrane. J Biol Chem. 2020;295:5163-5174 pubmed publisher
|
| Chang Z, Hou A, Chen Y. Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands. Nat Protoc. 2020;15:1507-1524 pubmed publisher
|
| Janssen A, Villacorta Hidalgo J, Beringer D, van Dooremalen S, Fernando F, van Diest E, et al. γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity. Cancer Immunol Res. 2020;8:530-543 pubmed publisher
|
| Kwon M, Kim C, Lee H, Cho H, Kim Y, Lee E, et al. PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors. Clin Cancer Res. 2020;26:1644-1655 pubmed publisher
|
| Wang W, Cohen J, Wallrapp A, Trieu K, Barrios J, Shao F, et al. Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung. Immunity. 2019;51:1102-1118.e7 pubmed publisher
|
| Levring T, Kongsbak Wismann M, Rode A, Al Jaberi F, Lopez D, Met O, et al. Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells. Sci Rep. 2019;9:16725 pubmed publisher
|
| Davies S, Reynolds G, Wilkinson A, Li X, Rose R, Leekha M, et al. Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process. Cell Rep. 2019;29:1610-1620.e4 pubmed publisher
|
| Rossatti P, Ziegler L, Schregle R, Betzler V, Ecker M, Rossy J. Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane. Cells. 2019;8: pubmed publisher
|
| Burchiel S, Lauer F, Factor Litvak P, Liu X, Santella R, Eunus M, et al. An increase in circulating B cells and B cell activation markers in peripheral blood is associated with cigarette smoking in a male cohort in Bangladesh. Toxicol Appl Pharmacol. 2019;384:114783 pubmed publisher
|
| Esfahani K, Al Aubodah T, Thebault P, Lapointe R, Hudson M, Johnson N, et al. Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation. Nat Commun. 2019;10:4712 pubmed publisher
|
| Tanaskovic O, Verga Falzacappa M, Pelicci P. Human cord blood (hCB)-CD34+ humanized mice fail to reject human acute myeloid leukemia cells. PLoS ONE. 2019;14:e0217345 pubmed publisher
|
| Gomez Lopez N, Romero R, Xu Y, Miller D, Arenas Hernandez M, Garcia Flores V, et al. Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth. J Immunol. 2019;203:1793-1807 pubmed publisher
|
| Han L, Hu J, Ma B, Wen D, Zhang T, Lu Z, et al. IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto's thyroiditis. Diagn Pathol. 2019;14:52 pubmed publisher
|
| Zhang L, Yu J. Triptolide reverses helper T cell inhibition and down-regulates IFN-γ induced PD-L1 expression in glioma cell lines. J Neurooncol. 2019;143:429-436 pubmed publisher
|
| Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed publisher
|
| Atay C, Kwak T, Lavilla Alonso S, Donthireddy L, Richards A, Moberg V, et al. BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells. Clin Cancer Res. 2019;25:2783-2794 pubmed publisher
|
| Davis D, Shrestha P, Aisabor A, Stream A, Galli V, Pise Masison C, et al. Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells. Oncoimmunology. 2019;8:e1546544 pubmed publisher
|
| Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H. HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. Cell Chem Biol. 2019;26:331-339.e3 pubmed publisher
|
| Tran H, Herz C, Ruf P, Stetter R, Lamy E. Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes. Front Immunol. 2018;9:2949 pubmed publisher
|
| Bamidele A, Svingen P, Sagstetter M, Sarmento O, González M, Braga Neto M, et al. Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. Cell Mol Gastroenterol Hepatol. 2019;7:55-71 pubmed publisher
|
| Li Y, Tan S, Zhang C, Chai Y, He M, Zhang C, et al. Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep. 2018;25:909-920.e4 pubmed publisher
|
| Cao M, Wang C, Chung W, Motabar D, Wang J, Christian E, et al. Characterization and analysis of scFv-IgG bispecific antibody size variants. MAbs. 2018;10:1236-1247 pubmed publisher
|
| Idelson M, Alper R, Obolensky A, Yachimovich Cohen N, Rachmilewitz J, Ejzenberg A, et al. Immunological Properties of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. Stem Cell Reports. 2018;11:681-695 pubmed publisher
|
| Cha J, Yang W, Xia W, Wei Y, Chan L, Lim S, et al. Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Mol Cell. 2018;71:606-620.e7 pubmed publisher
|
| Boutboul D, Kuehn H, Van de Wyngaert Z, Niemela J, Callebaut I, Stoddard J, et al. Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. J Clin Invest. 2018;128:3071-3087 pubmed publisher
|
| Pan H, Liu J, Deng W, Xing J, Li Q, Wang Z. Site-specific PEGylation of an anti-CEA/CD3 bispecific antibody improves its antitumor efficacy. Int J Nanomedicine. 2018;13:3189-3201 pubmed publisher
|
| Song H, Giorgi E, Ganusov V, Cai F, Athreya G, Yoon H, et al. Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. Nat Commun. 2018;9:1928 pubmed publisher
|
| Compeer E, Kraus F, Ecker M, Redpath G, Amiezer M, Rother N, et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun. 2018;9:1597 pubmed publisher
|
| Shi Y, Zhang P, Wang G, Liu X, Sun X, Zhang X, et al. Description of organ-specific phenotype, and functional characteristics of tissue resident lymphocytes from liver transplantation donor and research on immune tolerance mechanism of liver. Oncotarget. 2018;9:15552-15565 pubmed publisher
|
| Holien T, Gederaas O, Darvekar S, Christensen E, Peng Q. Comparison between 8-methoxypsoralen and 5-aminolevulinic acid in killing T cells of photopheresis patients ex vivo. Lasers Surg Med. 2018;50:469-475 pubmed publisher
|
| Carpier J, Zucchetti A, Bataille L, Dogniaux S, Shafaq Zadah M, Bardin S, et al. Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. J Exp Med. 2018;215:1245-1265 pubmed publisher
|
| Seki A, Rutz S. Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells. J Exp Med. 2018;215:985-997 pubmed publisher
|
| Martin S, Wick D, Nielsen J, Little N, Holt R, Nelson B. A library-based screening method identifies neoantigen-reactive T cells in peripheral blood prior to relapse of ovarian cancer. Oncoimmunology. 2017;7:e1371895 pubmed publisher
|
| Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
|
| Sawicka A, Babataheri A, Dogniaux S, Barakat A, González Rodríguez D, Hivroz C, et al. Micropipette force probe to quantify single-cell force generation: application to T-cell activation. Mol Biol Cell. 2017;28:3229-3239 pubmed publisher
|
| Hayashi T, Jean M, Huang H, Simpson S, Santoso N, Zhu J. Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription. Antiviral Res. 2017;146:76-85 pubmed publisher
|
| Tsai A, Khan A, Worgo C, Wang L, Liang Y, Davila E. A Multikinase and DNA-PK Inhibitor Combination Immunomodulates Melanomas, Suppresses Tumor Progression, and Enhances Immunotherapies. Cancer Immunol Res. 2017;5:790-803 pubmed publisher
|
| Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw A, et al. Astrocytic tight junctions control inflammatory CNS lesion pathogenesis. J Clin Invest. 2017;127:3136-3151 pubmed publisher
|
| Bughani U, Saha A, Kuriakose A, Nair R, Sadashivarao R, Venkataraman R, et al. T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab. PLoS ONE. 2017;12:e0180088 pubmed publisher
|
| Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, et al. A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Front Microbiol. 2017;8:1035 pubmed publisher
|
| Zheng C, Zheng L, Yoo J, Guo H, Zhang Y, Guo X, et al. Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing. Cell. 2017;169:1342-1356.e16 pubmed publisher
|
| Saitakis M, Dogniaux S, Goudot C, Bufi N, Asnacios S, Maurin M, et al. Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity. elife. 2017;6: pubmed publisher
|
| Hernández Del Pino R, Pellegrini J, Rovetta A, Peña D, Álvarez G, Rolandelli A, et al. Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses. Immunol Cell Biol. 2017;95:716-728 pubmed publisher
|
| Tello Lafoz M, MartÃnez MartÃnez G, RodrÃguez RodrÃguez C, Albar J, Huse M, Gharbi S, et al. Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse. Traffic. 2017;18:491-504 pubmed publisher
|
| Seignez A, Joly A, Chaumonnot K, Hazoume A, Sanka M, Marcion G, et al. Serum Gp96 is a chaperone of complement-C3 during graft-versus-host disease. JCI Insight. 2017;2:e90531 pubmed publisher
|
| Datlinger P, Rendeiro A, Schmidl C, Krausgruber T, Traxler P, Klughammer J, et al. Pooled CRISPR screening with single-cell transcriptome readout. Nat Methods. 2017;14:297-301 pubmed publisher
|
| Chen J, Wang Q, Feng X, Zhang Z, Geng L, Xu T, et al. Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria. Stem Cells Int. 2016;2016:4062789 pubmed publisher
|
| Cárcamo Orive I, Hoffman G, Cundiff P, Beckmann N, D Souza S, Knowles J, et al. Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. Cell Stem Cell. 2017;20:518-532.e9 pubmed publisher
|
| Zhu H, Hu F, Sun X, Zhang X, Zhu L, Liu X, et al. CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus. Front Immunol. 2016;7:512 pubmed
|
| Kiniry B, Ganesh A, Critchfield J, Hunt P, Hecht F, Somsouk M, et al. Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017;10:1008-1020 pubmed publisher
|
| Son C, Lee H, Koh E, Shin D, Bae J, Yang K, et al. Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells. Sci Rep. 2016;6:32470 pubmed publisher
|
| Guillou L, Babataheri A, Saitakis M, Bohineust A, Dogniaux S, Hivroz C, et al. T-lymphocyte passive deformation is controlled by unfolding of membrane surface reservoirs. Mol Biol Cell. 2016;27:3574-3582 pubmed
|
| Du S, Li Z, Chen C, Tan W, Chi Z, Kwang T, et al. Co-Expansion of Cytokine-Induced Killer Cells and V?9V?2 T Cells for CAR T-Cell Therapy. PLoS ONE. 2016;11:e0161820 pubmed publisher
|
| Pageon S, Nicovich P, Mollazade M, Tabarin T, Gaus K. Clus-DoC: a combined cluster detection and colocalization analysis for single-molecule localization microscopy data. Mol Biol Cell. 2016;27:3627-3636 pubmed
|
| Pageon S, Tabarin T, Yamamoto Y, Ma Y, Nicovich P, Bridgeman J, et al. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proc Natl Acad Sci U S A. 2016;113:E5454-63 pubmed publisher
|
| Starling S, Jolly C. LFA-1 Engagement Triggers T Cell Polarization at the HIV-1 Virological Synapse. J Virol. 2016;90:9841-9854 pubmed publisher
|
| You Y, Tan J, Dai H, Chen H, Xu X, Yang A, et al. MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma. Oncotarget. 2016;7:57099-57116 pubmed publisher
|
| Momose F, Seo N, Akahori Y, Sawada S, Harada N, Ogura T, et al. Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types. PLoS ONE. 2016;11:e0154134 pubmed publisher
|
| Siddiqui I, Erreni M, van Brakel M, Debets R, Allavena P. Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient. J Immunother Cancer. 2016;4:21 pubmed publisher
|
| Jones R, Mueller S, O Connor R, Rimpel K, Sloan D, Karel D, et al. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog. 2016;12:e1005545 pubmed publisher
|
| Pan Y, Wu Y, Ji J, Cai H, Wang H, Jiang Y, et al. Effect of cytokine-induced killer cells on immune function in patients with lung cancer. Oncol Lett. 2016;11:2827-2834 pubmed
|
| Kapoor Kaushik N, Hinde E, Compeer E, Yamamoto Y, Kraus F, Yang Z, et al. Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells. Front Immunol. 2016;7:83 pubmed publisher
|
| Li R, Yan F, Liu L, Li H, Ren B, Hui Z, et al. Cytokine-induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report. Oncol Lett. 2016;11:1885-1888 pubmed
|
| Liu Z, Han H, He X, Li S, Wu C, Yu C, et al. Expression of the galectin-9-Tim-3 pathway in glioma tissues is associated with the clinical manifestations of glioma. Oncol Lett. 2016;11:1829-1834 pubmed
|
| Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
|
| Frasca D, Ferracci F, Diaz A, Romero M, Lechner S, Blomberg B. Obesity decreases B cell responses in young and elderly individuals. Obesity (Silver Spring). 2016;24:615-25 pubmed publisher
|
| Martin M, Leffler J, Smoląg K, Mytych J, Björk A, Chaves L, et al. Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes. Cell Death Differ. 2016;23:903-11 pubmed publisher
|
| Soh K, Tario J, Colligan S, Maguire O, Pan D, Minderman H, et al. Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins. Curr Protoc Cytom. 2016;75:7.45.1-7.45.33 pubmed publisher
|
| Liu C, Jiang J, Gao L, Wang X, Hu X, Wu M, et al. Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways. Arthritis Res Ther. 2015;17:340 pubmed publisher
|
| Ramakrishna V, Sundarapandiyan K, Zhao B, Bylesjo M, Marsh H, Keler T. Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab. J Immunother Cancer. 2015;3:37 pubmed publisher
|
| Kuramitsu S, Ohno M, Ohka F, Shiina S, Yamamichi A, Kato A, et al. Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses. Cancer Gene Ther. 2015;22:487-95 pubmed publisher
|
| Silacci M, Lembke W, Woods R, Attinger Toller I, Baenziger Tobler N, Batey S, et al. Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases. MAbs. 2016;8:141-9 pubmed publisher
|
| Hsu P, Santner Nanan B, Hu M, Skarratt K, Lee C, Stormon M, et al. IL-10 Potentiates Differentiation of Human Induced Regulatory T Cells via STAT3 and Foxo1. J Immunol. 2015;195:3665-74 pubmed publisher
|
| Wienke J, Janssen W, Scholman R, Spits H, van Gijn M, Boes M, et al. A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation. Oncotarget. 2015;6:20037-42 pubmed
|
| Elkord E, Abd Al Samid M, Chaudhary B. Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP. Oncotarget. 2015;6:20026-36 pubmed
|
| Roberts R, Eitas T, Byrne J, Johnson B, Short P, McKinnon K, et al. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials. 2015;72:1-10 pubmed publisher
|
| Mikucki M, Fisher D, Matsuzaki J, Skitzki J, Gaulin N, Muhitch J, et al. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Nat Commun. 2015;6:7458 pubmed publisher
|
| Kim S, Theunissen J, Balibalos J, Liao Chan S, Babcock M, Wong T, et al. A novel antibody-drug conjugate targeting SAIL for the treatment of hematologic malignancies. Blood Cancer J. 2015;5:e316 pubmed publisher
|
| Tan Y, Deng J, Neilson J. RAX2: a genome-wide detection method of condition-associated transcription variation. Nucleic Acids Res. 2015;43:e96 pubmed publisher
|
| Ji Q, Salomon A. Wide-scale quantitative phosphoproteomic analysis reveals that cold treatment of T cells closely mimics soluble antibody stimulation. J Proteome Res. 2015;14:2082-9 pubmed publisher
|
| Vassena L, Giuliani E, Koppensteiner H, Bolduan S, Schindler M, Doria M. HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes. J Virol. 2015;89:5687-700 pubmed publisher
|
| McCracken M, Vatakis D, Dixit D, McLaughlin J, Zack J, Witte O. Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. J Clin Invest. 2015;125:1815-26 pubmed publisher
|
| Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler F, et al. Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway. elife. 2015;4: pubmed publisher
|
| Schultz H, Nitze L, Zeuthen L, Keller P, Gruhler A, Pass J, et al. Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor. J Immunol. 2015;194:3169-79 pubmed publisher
|
| Chauhan A, Chen C, Moore T, DiPaolo R. Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset. J Biol Chem. 2015;290:5127-40 pubmed publisher
|
| Cénit M, MartÃnez Florensa M, Consuegra M, Bonet L, Carnero Montoro E, Armiger N, et al. Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients. PLoS ONE. 2014;9:e113090 pubmed publisher
|
| Ji Q, Ding Y, Salomon A. SRC homology 2 domain-containing leukocyte phosphoprotein of 76 kDa (SLP-76) N-terminal tyrosine residues regulate a dynamic signaling equilibrium involving feedback of proximal T-cell receptor (TCR) signaling. Mol Cell Proteomics. 2015;14:30-40 pubmed publisher
|
| Kumaresan P, Manuri P, Albert N, Maiti S, Singh H, Mi T, et al. Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection. Proc Natl Acad Sci U S A. 2014;111:10660-5 pubmed publisher
|
| Quandt D, Jasinski Bergner S, Müller U, Schulze B, Seliger B. Synergistic effects of IL-4 and TNF? on the induction of B7-H1 in renal cell carcinoma cells inhibiting allogeneic T cell proliferation. J Transl Med. 2014;12:151 pubmed publisher
|
| Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, et al. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity. Cell Signal. 2014;26:2016-29 pubmed publisher
|
| Mellergaard M, Skovbakke S, Schneider C, Lauridsen F, Andresen L, Jensen H, et al. N-glycosylation of asparagine 8 regulates surface expression of major histocompatibility complex class I chain-related protein A (MICA) alleles dependent on threonine 24. J Biol Chem. 2014;289:20078-91 pubmed publisher
|
| Kang J, Wang P, Hwang P. Cell-based measurements of mitochondrial function in human subjects. Methods Enzymol. 2014;542:209-21 pubmed publisher
|
| Hartmann N, Giese N, Giese T, Poschke I, Offringa R, Werner J, et al. Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer. Clin Cancer Res. 2014;20:3422-33 pubmed publisher
|
| Wang D, Feng X, Lu L, Konkel J, Zhang H, Chen Z, et al. A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2234-45 pubmed publisher
|
| Mao C, Mou X, Zhou Y, Yuan G, Xu C, Liu H, et al. Tumor-activated TCR??? T cells from gastric cancer patients induce the antitumor immune response of TCR??? T cells via their antigen-presenting cell-like effects. J Immunol Res. 2014;2014:593562 pubmed publisher
|
| Guo Y, Riley K, Iwasaki A, Steitz J. Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Mol Cell. 2014;54:67-79 pubmed publisher
|
| Kim P, Jochems C, Grenga I, Donahue R, Tsang K, Gulley J, et al. Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy. J Immunol. 2014;192:2622-33 pubmed publisher
|
| Li L, Kim H, Nellore A, Patsoukis N, Petkova V, McDonough S, et al. Prostaglandin E2 promotes survival of naive UCB T cells via the Wnt/?-catenin pathway and alters immune reconstitution after UCBT. Blood Cancer J. 2014;4:e178 pubmed publisher
|
| Reichwald K, Jørgensen T, Tougaard P, Skov S. TL1A induces TCR independent IL-6 and TNF-? production and growth of PLZF? leukocytes. PLoS ONE. 2014;9:e85793 pubmed publisher
|
| Iversen T, Engell Noerregaard L, Ellebaek E, Andersen R, Larsen S, Bjoern J, et al. Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clin Cancer Res. 2014;20:221-32 pubmed publisher
|
| Hellinger R, Koehbach J, Fedchuk H, Sauer B, Huber R, Gruber C, et al. Immunosuppressive activity of an aqueous Viola tricolor herbal extract. J Ethnopharmacol. 2014;151:299-306 pubmed publisher
|
| Zhan H, Gilmour K, Chan L, Farzaneh F, McNicol A, Xu J, et al. Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene. PLoS ONE. 2013;8:e77106 pubmed publisher
|
| Kinoshita S, Kogure A, Taguchi S, Nolan G. Snapin, positive regulator of stimulation- induced Ca²? release through RyR, is necessary for HIV-1 replication in T cells. PLoS ONE. 2013;8:e75297 pubmed publisher
|
| Lin G, Field J, Yu J, Ken R, Neuberg D, Nathan D, et al. NF-?B is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors. PLoS ONE. 2013;8:e74664 pubmed publisher
|
| Kosmaczewska A, Ciszak L, Swierkot J, Szteblich A, Wiland P, Frydecka I. Alterations in both the activatory and inhibitory potential of peripheral blood CD4+ T cells in rheumatoid arthritis patients correlate with disease progression. Pathol Oncol Res. 2014;20:235-43 pubmed publisher
|
| Lindenberg J, Oosterhoff D, Sombroek C, Lougheed S, Hooijberg E, Stam A, et al. IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation. PLoS ONE. 2013;8:e70237 pubmed publisher
|
| Abrahamsson S, Angelini D, Dubinsky A, Morel E, Oh U, Jones J, et al. Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis. Brain. 2013;136:2888-903 pubmed publisher
|
| Singh H, Figliola M, Dawson M, Olivares S, Zhang L, Yang G, et al. Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells. PLoS ONE. 2013;8:e64138 pubmed publisher
|
| Lindenberg J, van de Ven R, Lougheed S, Zomer A, Santegoets S, Griffioen A, et al. Functional characterization of a STAT3-dependent dendritic cell-derived CD14+ cell population arising upon IL-10-driven maturation. Oncoimmunology. 2013;2:e23837 pubmed
|
| Rodriguez Plata M, Puigdomènech I, Izquierdo Useros N, Puertas M, Carrillo J, Erkizia I, et al. The infectious synapse formed between mature dendritic cells and CD4(+) T cells is independent of the presence of the HIV-1 envelope glycoprotein. Retrovirology. 2013;10:42 pubmed publisher
|
| Koelsch K, Wang Y, Maier Moore J, Sawalha A, Wren J. GFP affects human T cell activation and cytokine production following in vitro stimulation. PLoS ONE. 2013;8:e50068 pubmed publisher
|
| Chicaybam L, Sodré A, Curzio B, Bonamino M. An efficient low cost method for gene transfer to T lymphocytes. PLoS ONE. 2013;8:e60298 pubmed publisher
|
| Miller T, Kaur S, Ivins O Keefe K, Roberts D. Thrombospondin-1 is a CD47-dependent endogenous inhibitor of hydrogen sulfide signaling in T cell activation. Matrix Biol. 2013;32:316-24 pubmed publisher
|
| Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, et al. Functional characterization of EZH2? reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression. Epigenetics Chromatin. 2013;6:3 pubmed publisher
|
| Palin A, Ramachandran V, Acharya S, Lewis D. Human neonatal naive CD4+ T cells have enhanced activation-dependent signaling regulated by the microRNA miR-181a. J Immunol. 2013;190:2682-91 pubmed publisher
|
| Anangi R, Koshy S, Huq R, Beeton C, Chuang W, King G. Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers. PLoS ONE. 2012;7:e52965 pubmed publisher
|
| Zha B, Wang L, Liu X, Liu J, Chen Z, Xu J, et al. Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves' disease. PLoS ONE. 2012;7:e49835 pubmed publisher
|
| Li M, Cao W, Liu H, Zhang W, Liu X, Cai Z, et al. MCPIP1 down-regulates IL-2 expression through an ARE-independent pathway. PLoS ONE. 2012;7:e49841 pubmed publisher
|
| Olson B, Jankowska Gan E, Becker J, Vignali D, Burlingham W, McNeel D. Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. J Immunol. 2012;189:5590-601 pubmed publisher
|
| Cao L, Ding Y, Hung N, Yu K, Ritz A, Raphael B, et al. Quantitative phosphoproteomics reveals SLP-76 dependent regulation of PAG and Src family kinases in T cells. PLoS ONE. 2012;7:e46725 pubmed publisher
|
| Pennington M, Harunur Rashid M, Tajhya R, Beeton C, Kuyucak S, Norton R. A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3. FEBS Lett. 2012;586:3996-4001 pubmed publisher
|
| Bahri R, Bollinger A, Bollinger T, Orinska Z, Bulfone Paus S. Ectonucleotidase CD38 demarcates regulatory, memory-like CD8+ T cells with IFN-?-mediated suppressor activities. PLoS ONE. 2012;7:e45234 pubmed publisher
|
| Larochelle C, Cayrol R, Kebir H, Alvarez J, Lécuyer M, Ifergan I, et al. Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system. Brain. 2012;135:2906-24 pubmed publisher
|
| Bandyopadhyay G, Bankey P, Miller Graziano C. Trauma patients' elevated tumor necrosis related apoptosis inducing ligand (TRAIL) contributes to increased T cell apoptosis. Clin Immunol. 2012;145:44-54 pubmed publisher
|
| Rowin J, Thiruppathi M, Arhebamen E, Sheng J, Prabhakar B, Meriggioli M. Granulocyte macrophage colony-stimulating factor treatment of a patient in myasthenic crisis: effects on regulatory T cells. Muscle Nerve. 2012;46:449-53 pubmed publisher
|
| Forget M, Huon Y, Reuben A, Grange C, Liberman M, Martin J, et al. Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype. PLoS ONE. 2012;7:e41074 pubmed publisher
|
| Zhang T, Wu M, Sentman C. An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo. J Immunol. 2012;189:2290-9 pubmed publisher
|
| Bikker A, Moret F, Kruize A, Bijlsma J, Lafeber F, van Roon J. IL-7 drives Th1 and Th17 cytokine production in patients with primary SS despite an increase in CD4 T cells lacking the IL-7R?. Rheumatology (Oxford). 2012;51:996-1005 pubmed publisher
|
| Ioannou M, Alissafi T, Lazaridis I, Deraos G, Matsoukas J, Gravanis A, et al. Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease. J Immunol. 2012;188:1136-46 pubmed publisher
|
| Miller T, Wang E, Gould S, Stein E, Kaur S, Lim L, et al. Hydrogen sulfide is an endogenous potentiator of T cell activation. J Biol Chem. 2012;287:4211-21 pubmed publisher
|
| Tacke R, Lee H, Goh C, Courtney J, Polyak S, Rosen H, et al. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology. 2012;55:343-53 pubmed publisher
|
| Kirshberg S, Izhar U, Amir G, Demma J, Vernea F, Beider K, et al. Involvement of CCR6/CCL20/IL-17 axis in NSCLC disease progression. PLoS ONE. 2011;6:e24856 pubmed publisher
|
| Williams K, Dotson A, Otto A, Kohlmeier J, Benedict S. Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation. Cell Immunol. 2011;271:418-27 pubmed publisher
|
| Magrini E, Szabo I, Doni A, Cibella J, Viola A. Serotonin-mediated tuning of human helper T cell responsiveness to the chemokine CXCL12. PLoS ONE. 2011;6:e22482 pubmed publisher
|
| Landrigan A, Wong M, Utz P. CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol. 2011;187:3033-43 pubmed publisher
|
| Pollara J, Hart L, Brewer F, Pickeral J, Packard B, Hoxie J, et al. High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. Cytometry A. 2011;79:603-12 pubmed publisher
|
| Birzele F, Fauti T, Stahl H, Lenter M, Simon E, Knebel D, et al. Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human. Nucleic Acids Res. 2011;39:7946-60 pubmed publisher
|
| Mkhikian H, Grigorian A, Li C, Chen H, Newton B, Zhou R, et al. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nat Commun. 2011;2:334 pubmed publisher
|
| de la Fuente M, Recher M, Rider N, Strauss K, Morton D, Adair M, et al. Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia. J Allergy Clin Immunol. 2011;128:139-146 pubmed publisher
|
| Merims S, Li X, Joe B, Dokouhaki P, Han M, Childs R, et al. Anti-leukemia effect of ex vivo expanded DNT cells from AML patients: a potential novel autologous T-cell adoptive immunotherapy. Leukemia. 2011;25:1415-22 pubmed publisher
|
| Jin Z, Maiti S, Huls H, Singh H, Olivares S, Mátés L, et al. The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor. Gene Ther. 2011;18:849-56 pubmed publisher
|
| Quandt D, Fiedler E, Boettcher D, Marsch W, Seliger B. B7-h4 expression in human melanoma: its association with patients' survival and antitumor immune response. Clin Cancer Res. 2011;17:3100-11 pubmed publisher
|
| Wei J, Wu A, Kong L, Wang Y, Fuller G, Fokt I, et al. Hypoxia potentiates glioma-mediated immunosuppression. PLoS ONE. 2011;6:e16195 pubmed publisher
|
| Comin Anduix B, Chodon T, Sazegar H, Matsunaga D, Mock S, Jalil J, et al. The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations. Clin Cancer Res. 2010;16:6040-8 pubmed publisher
|
| Baeke F, Korf H, Overbergh L, Verstuyf A, Thorrez L, Van Lommel L, et al. The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation. J Immunol. 2011;186:132-42 pubmed publisher
|
| Tario J, Muirhead K, Pan D, Munson M, Wallace P. Tracking immune cell proliferation and cytotoxic potential using flow cytometry. Methods Mol Biol. 2011;699:119-64 pubmed publisher
|
| Parmigiani A, Pallin M, Schmidtmayerova H, Lichtenheld M, Pahwa S. Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells. Hum Immunol. 2011;72:115-23 pubmed publisher
|
| Marquet J, Lasoudris F, Cousin C, Puiffe M, Martin Garcia N, Baud V, et al. Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes. Eur J Immunol. 2010;40:2557-68 pubmed publisher
|
| Wu A, Wei J, Kong L, Wang Y, Priebe W, Qiao W, et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol. 2010;12:1113-25 pubmed publisher
|
| Hislop A, Palendira U, Leese A, Arkwright P, Rohrlich P, Tangye S, et al. Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets. Blood. 2010;116:3249-57 pubmed publisher
|
| Knight A, Madrigal A, Grace S, Sivakumaran J, Kottaridis P, Mackinnon S, et al. The role of V?2-negative ?? T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation. Blood. 2010;116:2164-72 pubmed publisher
|
| Richardt Pargmann D, Wechsler M, Krieg A, Vollmer J, Jurk M. Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment. Immunobiology. 2011;216:12-23 pubmed publisher
|
| Pan W, Zhu S, Yuan M, Cui H, Wang L, Luo X, et al. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol. 2010;184:6773-81 pubmed publisher
|
| Stevens C, Simeone A, John S, Ahmed Z, Lucherini O, Baldari C, et al. T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation. Biochem J. 2010;428:429-37 pubmed publisher
|
| Wei J, Barr J, Kong L, Wang Y, Wu A, Sharma A, et al. Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway. Mol Cancer Ther. 2010;9:67-78 pubmed publisher
|
| Godin Ethier J, Pelletier S, Hanafi L, Gannon P, Forget M, Routy J, et al. Human activated T lymphocytes modulate IDO expression in tumors through Th1/Th2 balance. J Immunol. 2009;183:7752-60 pubmed publisher
|
| Stahl H, Fauti T, Ullrich N, Bopp T, Kubach J, Rust W, et al. miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression. PLoS ONE. 2009;4:e7158 pubmed publisher
|
| Gur Wahnon D, Borovsky Z, Liebergall M, Rachmilewitz J. The induction of APC with a distinct tolerogenic phenotype via contact-dependent STAT3 activation. PLoS ONE. 2009;4:e6846 pubmed publisher
|
| Andersen M, Sørensen R, Brimnes M, Svane I, Becker J, thor Straten P. Identification of heme oxygenase-1-specific regulatory CD8+ T cells in cancer patients. J Clin Invest. 2009;119:2245-56 pubmed
|
| Nguyen V, Cao L, Lin J, Hung N, Ritz A, Yu K, et al. A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Mol Cell Proteomics. 2009;8:2418-31 pubmed publisher
|
| Mailer R, Falk K, Rotzschke O. Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity. PLoS ONE. 2009;4:e6104 pubmed publisher
|
| Correia D, d Orey F, Cardoso B, Lança T, Grosso A, deBarros A, et al. Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. PLoS ONE. 2009;4:e5657 pubmed publisher
|
| Takamatsu H, Espinoza J, Lu X, Qi Z, Okawa K, Nakao S. Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma. J Immunol. 2009;182:703-10 pubmed
|
| Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger E, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol. 2009;182:259-73 pubmed
|
| Puhar A, Dal Molin F, Horvath S, Ladant D, Ladants D, Montecucco C. Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases. PLoS ONE. 2008;3:e3564 pubmed publisher
|
| Sadri N, Schneider R. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol. 2009;129:657-70 pubmed publisher
|
| Zappasodi R, Di Nicola M, Carlo Stella C, Mortarini R, Molla A, Vegetti C, et al. The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the induction of ex vivo expansion of functional human antitumor T cells. Haematologica. 2008;93:1523-34 pubmed publisher
|
| Turul T, Tezcan I, Artac H, de Bruin Versteeg S, Barendregt B, Reisli I, et al. Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency. Eur J Pediatr. 2009;168:87-93 pubmed publisher
|
| Yu X, Sun J, He Y, Guo X, Liu S, Zhou B, et al. Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. Proc Natl Acad Sci U S A. 2007;104:19767-72 pubmed
|
| Chin L, Chu C, Chen H, Hsu S, Weng B, Chu C. Site-directed in vitro immunization leads to a complete human monoclonal IgG4 lambda that binds specifically to the CDR2 region of CTLA-4 (CD152) without interfering the engagement of natural ligands. BMC Biotechnol. 2007;7:51 pubmed
|
| Zeng H, Di L, Fu G, Chen Y, Gao X, Xu L, et al. Phosphorylation of Bcl10 negatively regulates T-cell receptor-mediated NF-kappaB activation. Mol Cell Biol. 2007;27:5235-45 pubmed
|