Human TIGAR-TAT Recombinant Protein, PeproTech | Invitrogen 150-14T-25UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human TIGAR-TAT Recombinant Protein, PeproTech

catalog :

150-14T-25UG

quantity :

25 ug

price :

US 227.00

citations: 1

Reference
Cheung E, DeNicola G, Nixon C, Blyth K, Labuschagne C, Tuveson D, et al. Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. 2020;37:168-182.e4 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human TIGAR-TAT Recombinant Protein, PeproTech

Catalog # :

150-14T-25UG

Quantity :

25 ug

Price :

US 227.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Functional Assay: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other intracellular proteins into primary, as well as transformed, cells.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

TIGAR