CD278 (ICOS) Monoclonal Antibody (C398.4A), PE-Cyanine5, eBioscience | Invitrogen 15-9949-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD278 (ICOS) Monoclonal Antibody (C398.4A), PE-Cyanine5, eBioscience

catalog :

15-9949-82

quantity :

100 µg

price :

US 327

clonality :

monoclonal

host :

hamsters

conjugate :

PE-Cy5

clone name :

C398.4A

reactivity :

human, mouse, rat, rhesus macaque

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:50; loading ...	Mathew D, Giles J, Baxter A, Greenplate A, Wu J, Alanio C, et al. Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions. bioRxiv. 2020;: pubmed publisher
	Beltra J, Manne S, Abdel Hakeem M, Kurachi M, Giles J, Chen Z, et al. Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. Immunity. 2020;52:825-841.e8 pubmed publisher
	Knolle M, Chin S, Rana B, Englezakis A, Nakagawa R, Fallon P, et al. MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity. Front Immunol. 2018;9:2232 pubmed publisher
	Cho S, Lee H, Yu I, Choi Y, Huang H, Hashemifar S, et al. Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nat Commun. 2018;9:2757 pubmed publisher
	Hao Y, Wang Y, Liu X, Yang X, Wang P, Tian Q, et al. The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4+ T Cells During Viral Infection. Front Immunol. 2018;9:1127 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD278 (ICOS) Monoclonal Antibody (C398.4A), PE-Cyanine5, eBioscience

Catalog # :

15-9949-82

Quantity :

100 µg

Price :

US 327

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Armenian Hamster

Reactivity :

Mouse, Rat, Rhesus Monkey

Applications :

Flow Cytometry: 0.06 µg/test

Species :

Mouse, Rat, Rhesus Monkey

Clone :

C398.4A

Isotype :

IgG

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.06 µg/test

Aliases :

Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115

more info or order :

Invitrogen product webpage