This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD278 (ICOS) Monoclonal Antibody (7E.17G9), PE-Cyanine5, eBioscience
catalog :
15-9942-82
quantity :
100 ug
price :
US 357.00
clonality :
monoclonal
host :
rat
conjugate :
PE-Cy5
clone name :
7E.17G9

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 11
Reference
Zhang Y, Liu T, Deng Z, Fang W, Zhang X, Zhang S, et al. Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils. Adv Sci (Weinh). 2023;10:e2206958 pubmed publisher
Demeyer A, Skordos I, Driege Y, Kreike M, Hochepied T, Baens M, et al. MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner. Front Immunol. 2019;10:1898 pubmed publisher
Chen S, Fang L, Guo W, Zhou Y, Yu G, Li W, et al. Control of Treg cell homeostasis and immune equilibrium by Lkb1 in dendritic cells. Nat Commun. 2018;9:5298 pubmed publisher
Essig K, Kronbeck N, Guimaraes J, Lohs C, Schlundt A, Hoffmann A, et al. Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation. Nat Commun. 2018;9:3810 pubmed publisher
Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
Graham J, Swarts J, Lund J. A Mouse Model of West Nile Virus Infection. Curr Protoc Mouse Biol. 2017;7:221-235 pubmed publisher
Deng R, Hurtz C, Song Q, Yue C, Xiao G, Yu H, et al. Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nat Commun. 2017;8:978 pubmed publisher
Kim K, Bae S, Capece T, Nedelkovska H, de Rubio R, Smrcka A, et al. Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment. Nat Commun. 2017;8:15365 pubmed publisher
Jin R, Blair S, Warunek J, Heffner R, Blader I, Wohlfert E. Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection. J Immunol. 2017;198:352-362 pubmed
Khan A, Hams E, Floudas A, Sparwasser T, Weaver C, Fallon P. PD-L1hi B cells are critical regulators of humoral immunity. Nat Commun. 2015;6:5997 pubmed publisher
Hams E, McCarron M, Amu S, Yagita H, Azuma M, Chen L, et al. Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. J Immunol. 2011;186:5648-55 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD278 (ICOS) Monoclonal Antibody (7E.17G9), PE-Cyanine5, eBioscience
Catalog # :
15-9942-82
Quantity :
100 ug
Price :
US 357.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Mouse
Clone :
7E.17G9
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA