CD80 (B7-1) Monoclonal Antibody (2D10.4), PE-Cyanine5, eBioscience | Invitrogen 15-0809-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD80 (B7-1) Monoclonal Antibody (2D10.4), PE-Cyanine5, eBioscience

catalog :

15-0809-42

quantity :

100 Tests

price :

US 376.00

clonality :

monoclonal

host :

mouse

conjugate :

PE-Cy5

clone name :

2D10.4

reactivity :

human

application :

flow cytometry

citations: 14

Reference
Yu B, de Vos D, Guo X, Peng S, Xie W, Peppelenbosch M, et al. IL-6 facilitates cross-talk between epithelial cells and tumor- associated macrophages in Helicobacter pylori-linked gastric carcinogenesis. Neoplasia. 2024;50:100981 pubmed publisher
Cuenca Escalona J, Fl xf3 rez Grau G, van den Dries K, Cambi A, de Vries I. PGE2-EP4 signaling steers cDC2 maturation toward the induction of suppressive T-cell responses. Eur J Immunol. 2024;54:e2350770 pubmed publisher
Elsayed R, Elashiry M, Tran C, Yang T, Carroll A, Liu Y, et al. Engineered Human Dendritic Cell Exosomes as Effective Delivery System for Immune Modulation. Int J Mol Sci. 2023;24: pubmed publisher
Lee J, Fra Bido S, Burton A, Innocentin S, Hill D, Linterman M. B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction. Aging Cell. 2022;21:e13692 pubmed publisher
Sanjay -, Shin J, Park M, Lee H. Cyanidin-3-O-Glucoside Regulates the M1/M2 Polarization of Microglia via PPARγ and Aβ42 Phagocytosis Through TREM2 in an Alzheimer's Disease Model. Mol Neurobiol. 2022;59:5135-5148 pubmed publisher
Yang C, Ming Y, Zhou K, Hao Y, Hu D, Chu B, et al. Macrophage Membrane-Camouflaged shRNA and Doxorubicin: A pH-Dependent Release System for Melanoma Chemo-Immunotherapy. Research (Wash D C). 2022;2022:9768687 pubmed publisher
Lai C, Tseng P, Chen C, Satria R, Wang Y, Lin C. Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages. J Inflamm Res. 2021;14:5241-5249 pubmed publisher
Li L, Liao Z, Ye M, Jiang J. Recombinant human IL-37 inhibited endometriosis development in a mouse model through increasing Th1/Th2 ratio by inducing the maturation of dendritic cells. Reprod Biol Endocrinol. 2021;19:128 pubmed publisher
Nazitto R, Amon L, Mast F, Aitchison J, Aderem A, Johnson J, et al. ILF3 Is a Negative Transcriptional Regulator of Innate Immune Responses and Myeloid Dendritic Cell Maturation. J Immunol. 2021;: pubmed publisher
Mikhalkevich N, O Carroll I, Tkavc R, Lund K, Sukumar G, Dalgard C, et al. Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses. PLoS Pathog. 2021;17:e1009305 pubmed publisher
Bamodu O, Kuo K, Wang C, Huang W, Wu A, Tsai J, et al. Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer. Nutrients. 2019;11: pubmed publisher
Zhang F, Zhu Y, Fan G, Hu S. Photodynamic therapy reduces the inhibitory effect of osteosarcoma cells on dendritic cells by upregulating HSP70. Oncol Lett. 2018;16:5034-5040 pubmed publisher
Schmitt D, O Dee D, Horzempa J, Carlson P, Russo B, Bales J, et al. A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy. PLoS ONE. 2012;7:e31172 pubmed publisher
Bashuda H, Kimikawa M, Seino K, Kato Y, Ono F, Shimizu A, et al. Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates. J Clin Invest. 2005;115:1896-902 pubmed

product information

Product Type :

Antibody

Product Name :

CD80 (B7-1) Monoclonal Antibody (2D10.4), PE-Cyanine5, eBioscience

Catalog # :

15-0809-42

Quantity :

100 Tests

Price :

US 376.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (1 ug)/test

Species :

Human

Clone :

2D10.4

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (1 ug)/test

Aliases :

Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1