Human/Mouse/Rat Thymosin-beta4 Recombinant Protein, PeproTech | Invitrogen 140-14-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human/Mouse/Rat Thymosin-beta4 Recombinant Protein, PeproTech

catalog :

140-14-100UG

quantity :

100 ug

price :

US 227.00

citations: 1

Reference
Lari G, Nowicka E, Morgan D, Kondrat S, Hutchings G. The use of carbon monoxide as a probe molecule in spectroscopic studies for determination of exposed gold sites on TiO2. Phys Chem Chem Phys. 2015;17:23236-44 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human/Mouse/Rat Thymosin-beta4 Recombinant Protein, PeproTech

Catalog # :

140-14-100UG

Quantity :

100 ug

Price :

US 227.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human, Mouse, Rat

Applications :

Functional Assay: Assay-dependent

Species :

Human, Mouse, Rat

Storage :

-20 C

Description :

Thymosin-beta4 is a small, actin-sequestering protein belonging to the thymosin-beta family that is found at high concentrations within the spleen, thymus, and peritoneal macrophages, where it is most notably responsible for the organization of cytoskeletal structure. In mammalian tissues, this protein acts as a modulator for the polymerization/depolymerization of actin through the formation of a 1:1 complex with the monomer G (globular)-actin, and inhibits actin's polymerization to form F (filamentous) actin, which together with other proteins binds microfilaments to construct the cytoskeleton. Commonly found at significant quantities within the brain, lungs, liver, kidneys, testes, and heart, thymosin-beta4 has also been shown to be synthesized by cells unrelated to the reticuloendothelial system, such as myoblasts and fibroblasts, and expressed at irregular levels by several hemopoietic cell lines, malignant lymphoid cells and myeloma cells. In addition to regulating actin polymerization, research has also found thymosin-beta4 to stimulate the secretion of hypothalamic luteinizing hormone-releasing hormone and luteinizing hormone, inhibit the migration of peritoneal macrophages, induce phenotypic changes in T cell lines during early host defense mechanisms, and inhibit the progression of hematopoietic pluripotent stem cells into the S-phase.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

Fx; Hematopoietic system regulatory peptide; prothymosin beta 4; prothymosin beta-4; Ptmb4; Seraspenide; T beta 4; t beta-4; Tb4; TB4X; TB4Xbeta 4; Thyb4; thymosin; thymosin beta 4; thymosin beta 4, X-linked; thymosin beta-4; thymosin, beta 4, X chromosome; Tmsb4; Tmsb4x