FDC Monoclonal Antibody (CNA.42), eBioscience | Invitrogen 14-9968-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FDC Monoclonal Antibody (CNA.42), eBioscience

catalog :

14-9968-80

quantity :

25 µg

price :

US 120

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CNA.42

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human	Noort A, van Zoest K, van Baarsen L, Maracle C, Helder B, Papazian N, et al. Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-ÎºB-Inducing Kinase-Positive Endothelial Cells as Central Players. Am J Pathol. 2015;185:1935-43 pubmed publisher
	Aly N, Rizk S, Aboul Enein A, El Desoukey N, Zawam H, Ahmed M, et al. The role of lymphoid tissue SPARC in the pathogenesis and response to treatment of multiple myeloma. Front Oncol. 2022;12:1009993 pubmed publisher
	El Shikh M, El Sayed R, Aly N, Prediletto E, Hands R, Fossati Jimack L, et al. Follicular dendritic cell differentiation is associated with distinct synovial pathotype signatures in rheumatoid arthritis. Front Med (Lausanne). 2022;9:1013660 pubmed publisher
	Hase H, Kanno Y, Kojima M, Hasegawa K, Sakurai D, Kojima H, et al. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood. 2004;103:2257-65 pubmed
	Maeda K, Matsuda M, Suzuki H, Saitoh H. Immunohistochemical recognition of human follicular dendritic cells (FDCs) in routinely processed paraffin sections. J Histochem Cytochem. 2002;50:1475-86 pubmed
	Raymond I, Al Saati T, Tkaczuk J, Chittal S, Delsol G. CNA.42, a new monoclonal antibody directed against a fixative-resistant antigen of follicular dendritic reticulum cells. Am J Pathol. 1997;151:1577-85 pubmed

product information

Product Type :

Antibody

Product Name :

FDC Monoclonal Antibody (CNA.42), eBioscience

Catalog # :

14-9968-80

Quantity :

25 µg

Price :

US 120

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/Test, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: Assay-Dependent

Species :

Human

Clone :

CNA.42

Isotype :

IgM

Storage :

4° C

Description :

FDCs are large cells in germinal centers (GCs) of primary and lymphoid tissues. They present non-processed antigen and switch off apoptosis of B cells through a selection process resulting in selection of memory B cells. FDCs express many B cell markers such as CD21 (long isoform), CD23 and CD35. A role for FDCs as been shown in various infectious diseases such as AIDS and transmissible spongiform encephalitis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/Test, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: Assay-Dependent

Aliases :

Dendritic Cells; FDC

more info or order :

Invitrogen product webpage