Caspase 11 Monoclonal Antibody (17D9), eBioscience™ | Invitrogen 14-9935-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 11 Monoclonal Antibody (17D9), eBioscience™

catalog :

14-9935-82

quantity :

100 µg

price :

US 420

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

17D9

reactivity :

mouse

application :

western blot

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Kajiwara Y, Schiff T, Voloudakis G, Gama Sosa M, Elder G, Bozdagi O, et al. A critical role for human caspase-4 in endotoxin sensitivity. J Immunol. 2014;193:335-43 pubmed publisher
	Drummer C, Saaoud F, Jhala N, Cueto R, Sun Y, Xu K, et al. Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages. Front Immunol. 2023;14:1113883 pubmed publisher
	Chowdhury D, Gardner J, Satpati A, Nookala S, Mukundan S, Porollo A, et al. Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity. Front Immunol. 2021;12:755961 pubmed publisher
	Lee J, Kim Y, Ra H, Kang S, Han S, Koh J, et al. The involvement of caspase-11 in TPEN-induced apoptosis. FEBS Lett. 2008;582:1871-6 pubmed publisher
	Endo M, Mori M, Akira S, Gotoh T. C/EBP homologous protein (CHOP) is crucial for the induction of caspase-11 and the pathogenesis of lipopolysaccharide-induced inflammation. J Immunol. 2006;176:6245-53 pubmed

product information

Product Type :

Antibody

Product Name :

Caspase 11 Monoclonal Antibody (17D9), eBioscience™

Catalog # :

14-9935-82

Quantity :

100 µg

Price :

US 420

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Western Blot: 1-5 µg/mL

Species :

Mouse

Clone :

17D9

Isotype :

IgG2a

Storage :

4° C

Description :

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-5 µg/mL

Aliases :

apoptotic cysteine protease Mih1/TX; Casp11; CASP-11; CASP4; CASP-4; caspase 11; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; Caspase-11; Caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-4 subunit p20; Caspl; ICE and Ced-3 homolog 2; ICE(rel)II; ICE(rel)-II; ICEREL-II; ICH2; ICH-2; Ich3; ich-3; Mih1; Mih1/TX; protease ICH-2; Protease ICH-3; Protease TX; TX

more info or order :

Invitrogen product webpage