Caspase 7 Monoclonal Antibody (20F3), eBioscience | Invitrogen 14-9933-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 7 Monoclonal Antibody (20F3), eBioscience

catalog :

14-9933-80

quantity :

25 ug

price :

US 166.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

20F3

reactivity :

human

application :

western blot

citations: 3

Reference
Kim E, Hong H, Cho D, Han J, Kim S, Kim T. Enhancement of toll-like receptor 2-mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells. Immunology. 2011;134:73-81 pubmed publisher
Tago F, Tsukimoto M, Nakatsukasa H, Kojima S. Repeated 0.5-Gy gamma irradiation attenuates autoimmune disease in MRL-lpr/lpr mice with suppression of CD3+CD4-CD8-B220+ T-cell proliferation and with up-regulation of CD4+CD25+Foxp3+ regulatory T cells. Radiat Res. 2008;169:59-66 pubmed
Denault J, Bekes M, Scott F, Sexton K, Bogyo M, Salvesen G. Engineered hybrid dimers: tracking the activation pathway of caspase-7. Mol Cell. 2006;23:523-33 pubmed

product information

Product Type :

Antibody

Product Name :

Caspase 7 Monoclonal Antibody (20F3), eBioscience

Catalog # :

14-9933-80

Quantity :

25 ug

Price :

US 166.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Western Blot: 0.5-5 ug/mL

Species :

Human

Clone :

20F3

Isotype :

IgG2a

Storage :

4 C

Description :

Caspase 7 is part of a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase 7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression. Alternative splicing results in four transcript variants, encoding three distinct isoforms of Caspase 7. Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.5-5 ug/mL

Aliases :

AI314680; Apoptotic protease Mch-3; Casp7; CASP-7; caspase 7; caspase 7, apoptosis-related cysteine peptidase; caspase 7, apoptosis-related cysteine protease; caspase-7; Caspase-7 subunit p11; Caspase-7 subunit p20; CMH-1; cysteine protease LICE2; ICE-IAP3; ICE-LAP3; ICE-like apoptotic protease 3; Lice2; mCASP-7; MCH3; OTTHUMP00000020511; OTTHUMP00000020513; OTTHUMP00000020514; RP11-211N11.6