GFAP Monoclonal Antibody (GA5), eBioscience™ | Invitrogen 14-9892-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GFAP Monoclonal Antibody (GA5), eBioscience™

catalog :

14-9892-95

quantity :

10 mg

price :

US 3000.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GA5

reactivity :

human, mouse, rat, chicken, pigs , domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 10

Reference
Kosuge Y, Kaneko E, Nango H, Miyagishi H, Ishige K, Ito Y. Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev. 2020;2020:1020673 pubmed publisher
Wong C, Cheung N, Ho C, Barathi V, Storm G, Wong T. Characterisation of the inflammatory cytokine and growth factor profile in a rabbit model of proliferative vitreoretinopathy. Sci Rep. 2019;9:15419 pubmed publisher
Yan J, Zhao Q, Gabrusiewicz K, Kong L, Xia X, Wang J, et al. FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation. Nat Commun. 2019;10:448 pubmed publisher
Weider M, Starost L, Groll K, Küspert M, Sock E, Wedel M, et al. Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Nat Commun. 2018;9:899 pubmed publisher
Jamali N, Wang S, Darjatmoko S, Sorenson C, Sheibani N. Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3. PLoS ONE. 2017;12:e0190131 pubmed publisher
Wu L, Ye Z, Zhou C, Wang C, Xie G, Zhang X, et al. Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats. Front Mol Neurosci. 2017;10:175 pubmed publisher
Jin W, Shi S, Li Z, Li M, Wood K, Gonzales R, et al. Depletion of microglia exacerbates postischemic inflammation and brain injury. J Cereb Blood Flow Metab. 2017;37:2224-2236 pubmed publisher
Michaels D, Leibowitz J, Azaiza M, Shil P, Shama S, Kutish G, et al. Cellular Microbiology of Mycoplasma canis. Infect Immun. 2016;84:1785-1795 pubmed publisher
Wang C, Zhang F, Jiang S, Siedlak S, Shen L, Perry G, et al. Estrogen receptor-? is localized to neurofibrillary tangles in Alzheimer's disease. Sci Rep. 2016;6:20352 pubmed publisher
Vazquez Cintron E, Vakulenko M, Band P, Stanker L, Johnson E, Ichtchenko K. Atoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasm. PLoS ONE. 2014;9:e85517 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GFAP Monoclonal Antibody (GA5), eBioscience™

Catalog # :

14-9892-95

Quantity :

10 mg

Price :

US 3000.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Chicken, Human, Mouse, Porcine, Rabbit, Rat

Applications :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 0.5-5 µg/mL

Species :

Chicken, Human, Mouse, Porcine, Rabbit, Rat

Clone :

GA5

Isotype :

IgG1

Storage :

4° C

Description :

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 0.5-5 µg/mL

Aliases :

AI836096; ALXDRD; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; gfap; GFAP epsilon; gfap protein; gfapl; Glial fibrillary acidic protein; glial fibrillary acidic protein alpha; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen