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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
BCL6 Monoclonal Antibody (GI191E), eBioscience™
catalog :
14-9887-82
quantity :
100 µg
price :
US 420
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GI191E
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...
Tacconi C, He Y, Ducoli L, Detmar M. Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells. Angiogenesis. 2020;: pubmed publisher
  • flow cytometry; mouse
Wollenberg I, Agua Doce A, Hernandez A, Almeida C, Oliveira V, Faro J, et al. Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells. J Immunol. 2011;187:4553-60 pubmed publisher
Weber J, Fuhrmann F, Hutloff A. T-follicular helper cells survive as long-term memory cells. Eur J Immunol. 2012;42:1981-8 pubmed publisher
Duy C, Yu J, Nahar R, Swaminathan S, Kweon S, Polo J, et al. BCL6 is critical for the development of a diverse primary B cell repertoire. J Exp Med. 2010;207:1209-21 pubmed publisher
Johnston R, Poholek A, DiToro D, Yusuf I, Eto D, Barnett B, et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science. 2009;325:1006-10 pubmed publisher
Garcia J, Garcia J, Maestre L, Lucas E, Sanchez Verde L, Romero Chala S, et al. Genetic immunization: a new monoclonal antibody for the detection of BCL-6 protein in paraffin sections. J Histochem Cytochem. 2006;54:31-8 pubmed
product information
Product Type :
Antibody
Product Name :
BCL6 Monoclonal Antibody (GI191E), eBioscience™
Catalog # :
14-9887-82
Quantity :
100 µg
Price :
US 420
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1 µg/mL
Species :
Human, Mouse
Clone :
GI191E
Isotype :
IgG1, kappa
Storage :
4° C
Description :
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1 µg/mL
Aliases :
B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; BCL6; BCL-6; BCL6 transcription repressor; BCL6A; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; Zinc finger and BTB domain-containing protein 27; zinc finger protein 51; zinc finger transcription factor BCL6S; ZNF51
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA