This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cutaneous Lymphocyte Antigen (CLA) Monoclonal Antibody (HECA-452), eBioscience
catalog :
14-9857-82
quantity :
100 ug
price :
US 157.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
HECA-452

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 9
Reference
Kelkar A, Zhu Y, Groth T, Stolfa G, Stablewski A, Singhi N, et al. Doxycycline-Dependent Self-Inactivation of CRISPR-Cas9 to Temporally Regulate On- and Off-Target Editing. Mol Ther. 2019;: pubmed publisher
Palkola N, Pakkanen S, Kantele J, Pakarinen L, Puohiniemi R, Kantele A. Differences in Homing Potentials of Streptococcus pneumoniae-Specific Plasmablasts in Pneumococcal Pneumonia and After Pneumococcal Polysaccharide and Pneumococcal Conjugate Vaccinations. J Infect Dis. 2015;212:1279-87 pubmed publisher
Yamaguchi M, Takata K, Yoshino T, Ishizuka N, Oguchi M, Kobayashi Y, et al. Prognostic biomarkers in patients with localized natural killer/T-cell lymphoma treated with concurrent chemoradiotherapy. Cancer Sci. 2014;105:1435-41 pubmed publisher
Kantele A, Pakkanen S, Karttunen R, Kantele J. Head-to-head comparison of humoral immune responses to Vi capsular polysaccharide and Salmonella Typhi Ty21a typhoid vaccines--a randomized trial. PLoS ONE. 2013;8:e60583 pubmed publisher
Jayakumar D, Marathe D, Neelamegham S. Detection of site-specific glycosylation in proteins using flow cytometry. Cytometry A. 2009;75:866-73 pubmed publisher
Ku C, Zerboni L, Ito H, Graham B, Wallace M, Arvin A. Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha. J Exp Med. 2004;200:917-25 pubmed
Yago T, Leppanen A, Qiu H, Marcus W, Nollert M, Zhu C, et al. Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow. J Cell Biol. 2002;158:787-99 pubmed
Hunger R, Yawalkar N, Braathen L, Brand C. The HECA-452 epitope is highly expressed on lymph cells derived from human skin. Br J Dermatol. 1999;141:565-9 pubmed
Bos J, de Boer O, Tibosch E, Das P, Pals S. Skin-homing T lymphocytes: detection of cutaneous lymphocyte-associated antigen (CLA) by HECA-452 in normal human skin. Arch Dermatol Res. 1993;285:179-83 pubmed
product information
Product Type :
Antibody
Product Name :
Cutaneous Lymphocyte Antigen (CLA) Monoclonal Antibody (HECA-452), eBioscience
Catalog # :
14-9857-82
Quantity :
100 ug
Price :
US 157.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human
Applications :
Flow Cytometry: 0.125 ug/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: Assay-Dependent
Species :
Human
Clone :
HECA-452
Isotype :
IgM, kappa
Storage :
4 C
Description :
This cell surface glycoprotein is most highly expressed on T cells in the skin. Nevertheless, CLA can also be detected on some peripheral T and NK cells, as well as monocytes, neutrophils and CD1a+ dendritic cells. Studies have determined that this antibody recognizes sialofucosylated glycans and sialyl Lewis x (sLex). CLA, which binds E-selectin and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1), is involved in T lymphocyte infiltration and adhesion at cutaneous sites of inflammation.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 ug/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: Assay-Dependent
Aliases :
CLA
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA