SOX2 Monoclonal Antibody (Btjce), eBioscience™ | Invitrogen 14-9811-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX2 Monoclonal Antibody (Btjce), eBioscience™

catalog :

14-9811-95

quantity :

10 mg

price :

US 3000.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Btjce

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 8

Reference
Lazarus K, Hadi F, Zambon E, Bach K, Santolla M, Watson J, et al. BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma. Nat Commun. 2018;9:3327 pubmed publisher
Morgani S, Metzger J, Nichols J, Siggia E, Hadjantonakis A. Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. elife. 2018;7: pubmed publisher
Kurtenbach S, Ding W, Goss G, Hare J, Goldstein B, Shehadeh L. Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium. PLoS ONE. 2017;12:e0187576 pubmed publisher
Megaw R, Abu Arafeh H, JUNGNICKEL M, Mellough C, Gurniak C, Witke W, et al. Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models. Nat Commun. 2017;8:271 pubmed publisher
Jang S, Choubey S, Furchtgott L, Zou L, Doyle A, Menon V, et al. Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states. elife. 2017;6: pubmed publisher
Andersson Rolf A, Mustata R, Merenda A, Kim J, Perera S, Grego T, et al. One-step generation of conditional and reversible gene knockouts. Nat Methods. 2017;14:287-289 pubmed publisher
Alexandrova S, Kalkan T, Humphreys P, Riddell A, Scognamiglio R, Trumpp A, et al. Selection and dynamics of embryonic stem cell integration into early mouse embryos. Development. 2016;143:24-34 pubmed publisher
Yamamizu K, Schlessinger D, Ko M. SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1). Development. 2014;141:4254-66 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SOX2 Monoclonal Antibody (Btjce), eBioscience™

Catalog # :

14-9811-95

Quantity :

10 mg

Price :

US 3000.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1 µg/ml

Species :

Human, Mouse

Clone :

Btjce

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1 µg/ml

Aliases :

ANOP3; cb236; lcc; MCOPS3; RGD1565646; sex determining region Y-box 2; SOX 2; sox2; Sox-2; soxp; SRY (sex determining region Y)-box 2; SRY box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor Sox-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389