This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SOX2 Monoclonal Antibody (Btjce), eBioscience
catalog :
14-9811-37
quantity :
2 mg
price :
US 1496.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
Btjce
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 61
Reference
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Suong D, Imamura K, Inoue I, Kabai R, Sakamoto S, Okumura T, et al. Induction of inverted morphology in brain organoids by vertical-mixing bioreactors. Commun Biol. 2021;4:1213 pubmed publisher
Austin S, Gabarr xf3 Solanas R, Rigo P, Paun O, Harris L, Guillemot F, et al. Wnt/β-catenin signalling is dispensable for adult neural stem cell homeostasis and activation. Development. 2021;148: pubmed publisher
Liu C, Pan Z, Chen Q, Chen Z, Liu W, Wu L, et al. Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer. J Exp Clin Cancer Res. 2021;40:297 pubmed publisher
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Huang T, Iyer A, Manalo J, Woo J, Bosquez Huerta N, McGovern M, et al. Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis. J Neurosci. 2021;41:7171-7181 pubmed publisher
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Kojic M, Gawda T, Gaik M, Begg A, Salerno Kochan A, Kurniawan N, et al. Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype. Nat Commun. 2021;12:2678 pubmed publisher
Morgani S, Su J, Nichols J, Massague J, Hadjantonakis A. The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. elife. 2021;10: pubmed publisher
Sugiura A, Shimizu T, Kameyama T, Maruo T, Kedashiro S, Miyata M, et al. Identification of Sox2 and NeuN Double-Positive Cells in the Mouse Hypothalamic Arcuate Nucleus and Their Reduction in Number With Aging. Front Aging Neurosci. 2020;12:609911 pubmed publisher
Dzikowski L, Mirzaei R, Sarkar S, Kumar M, Bose P, Bellail A, et al. Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor-initiating cells. Brain Pathol. 2021;31:e12947 pubmed publisher
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Kasashima H, Duran A, Martínez Ordóñez A, Nakanishi Y, Kinoshita H, Linares J, et al. Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population. Dev Cell. 2021;56:95-110.e10 pubmed publisher
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Ahn L, Coatti G, Liu J, Gumus E, Schaffer A, Miranda H. An epilepsy-associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model. J Neurosci Res. 2021;99:110-123 pubmed publisher
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Morgani S, Hadjantonakis A. Spatially Organized Differentiation of Mouse Pluripotent Stem Cells on Micropatterned Surfaces. Methods Mol Biol. 2021;2214:41-58 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
SOX2 Monoclonal Antibody (Btjce), eBioscience
Catalog # :
14-9811-37
Quantity :
2 mg
Price :
US 1496.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1-5 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 0.2-1 ug/mL
Species :
Human, Mouse
Clone :
Btjce
Isotype :
IgG2a, kappa
Storage :
4 C
Description :
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1-5 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 0.2-1 ug/mL
Aliases :
ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA