This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Vinculin Monoclonal Antibody (7F9), eBioscience
catalog :
14-9777-37
quantity :
2 mg
price :
US 1482.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7F9

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 8
Reference
Kopsida M, Clavero A, Khaled J, Balgoma D, Luna Marco C, Chowdhury A, et al. Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells. Mol Metab. 2024;79:101846 pubmed publisher
De Munck D, Leloup A, De Moudt S, De Meyer G, Martinet W, Fransen P. Mouse aortic biomechanics are affected by short-term defective autophagy in vascular smooth muscle cells. J Physiol Sci. 2022;72:7 pubmed publisher
Cui H, Divakaran A, Hoell Z, Ellingson M, Scholtz C, Zahid H, et al. A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 2022;65:2342-2360 pubmed publisher
Balint B, Hergalant S, Camadro J, Blaise S, Vanalderwiert L, Ligni xe8 res L, et al. Fetal Programming by Methyl Donor Deficiency Produces Pathological Remodeling of the Ascending Aorta. Arterioscler Thromb Vasc Biol. 2021;41:1928-1941 pubmed publisher
Alshaabi H, Shannon N, Gravelle R, Milczarek S, Messier T, Cunniff B. Miro1-mediated mitochondrial positioning supports subcellular redox status. Redox Biol. 2021;38:101818 pubmed publisher
Pavlovic N, Calitz C, Thanapirom K, Mazza G, Rombouts K, Gerwins P, et al. Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma. elife. 2020;9: pubmed publisher
Chang C, Lee H, Lee C. Substrate properties modulate cell membrane roughness by way of actin filaments. Sci Rep. 2017;7:9068 pubmed publisher
Davis E, Kim J, Menasche B, Sheppard J, Liu X, Tan A, et al. Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins. Cell Rep. 2015;11:1727-36 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Vinculin Monoclonal Antibody (7F9), eBioscience
Catalog # :
14-9777-37
Quantity :
2 mg
Price :
US 1482.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Frozen): 5 ug/mL, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1-5 ug/mL
Species :
Human, Mouse, Rat
Clone :
7F9
Isotype :
IgG1, kappa
Storage :
4 C
Description :
Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Frozen): 5 ug/mL, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1-5 ug/mL
Aliases :
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA