Brachyury Monoclonal Antibody (X1AO2), eBioscience | Invitrogen 14-9770-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Brachyury Monoclonal Antibody (X1AO2), eBioscience

catalog :

14-9770-80

quantity :

25 ug

price :

US 166.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

X1AO2

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Huang B, Cohen J, Fernando R, Hamilton D, Litzinger M, Hodge J, et al. The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies. Cell Death Dis. 2013;4:e682 pubmed publisher
Roselli M, Fernando R, Guadagni F, Spila A, Alessandroni J, Palmirotta R, et al. Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer. Clin Cancer Res. 2012;18:3868-79 pubmed publisher
Fernando R, Litzinger M, Trono P, Hamilton D, Schlom J, Palena C. The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. J Clin Invest. 2010;120:533-44 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Brachyury Monoclonal Antibody (X1AO2), eBioscience

Catalog # :

14-9770-80

Quantity :

25 ug

Price :

US 166.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: Assay-Dependent

Species :

Human

Clone :

X1AO2

Isotype :

IgG2b, kappa

Storage :

4 C

Description :

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

Immunogen :

E.coli-derived fragment of human Brachyury corresponding to amino acids 237-348

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: Assay-Dependent

Aliases :

Bra; brachyury; brachyury homolog; brachyury protein; brachyury-like 2; brachyury-like 3; cou; D17Mit170; Low; low ratio; Lr; me75; Protein T; RP11-459F1.1; SAVA; T; T brachyury homolog; T brachyury transcription factor; T, brachyury homolog; T1; T-box transcription factor T; TBXT; TFT; Tl2; Tl3