Insulin Monoclonal Antibody (ICBTACLS), eBioscience™ | Invitrogen 14-9769-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Insulin Monoclonal Antibody (ICBTACLS), eBioscience™

catalog :

14-9769-82

quantity :

100µg

price :

US 345

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ICBTACLS

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1a	Anquetil F, Mondanelli G, Gonzalez N, Rodríguez Calvo T, Zapardiel Gonzalo J, Krogvold L, et al. Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes. Diabetes. 2018;67:1858-1866 pubmed publisher
	Abdelrazek H, Kilany O, Muhammad M, Tag H, Abdelazim A. Black Seed Thymoquinone Improved Insulin Secretion, Hepatic Glycogen Storage, and Oxidative Stress in Streptozotocin-Induced Diabetic Male Wistar Rats. Oxid Med Cell Longev. 2018;2018:8104165 pubmed publisher
	Banks W, Owen J, Erickson M. Insulin in the brain: there and back again. Pharmacol Ther. 2012;136:82-93 pubmed publisher
	Gillespie K. Type 1 diabetes: pathogenesis and prevention. CMAJ. 2006;175:165-70 pubmed

product information

Product Type :

Antibody

Product Name :

Insulin Monoclonal Antibody (ICBTACLS), eBioscience™

Catalog # :

14-9769-82

Quantity :

100µg

Price :

US 345

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 0.25 µg/mL, Western Blot: 5 µg/mL

Species :

Human, Mouse, Rat

Clone :

ICBTACLS

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.25 µg/mL, Western Blot: 5 µg/mL

Aliases :

AA986540; BOS_25069; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; Insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin

more info or order :

Invitrogen product webpage