Insulin Monoclonal Antibody (ICBTACLS), eBioscience | Invitrogen 14-9769-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Insulin Monoclonal Antibody (ICBTACLS), eBioscience

catalog :

14-9769-37

quantity :

2 mg

price :

US 1482.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ICBTACLS

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 8

Reference
Monzani P, Sangalli J, Sampaio R, Guemra S, Zanin R, Adona P, et al. Human proinsulin production in the milk of transgenic cattle. Biotechnol J. 2024;19:e2300307 pubmed publisher
Luo C, Hou C, Yang D, Tan T, Chao C. Urolithin C alleviates pancreatic β-cell dysfunction in type 1 diabetes by activating Nrf2 signaling. Nutr Diabetes. 2023;13:24 pubmed publisher
Buldak L, Machnik G, Skudrzyk E, Boldys A, Maliglowka M, Kosowski M, et al. Exenatide prevents statin-related LDL receptor increase and improves insulin secretion in pancreatic beta cells (1.1E7) in a protein kinase A-dependent manner. J Appl Biomed. 2022;20:130-140 pubmed publisher
Bayram P, Billur D, Kizil S, Caliskan H, Can B. Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome. Iran J Basic Med Sci. 2022;25:1308-1316 pubmed publisher
Peixoto Neves D, Kanthakumar P, Kumar R, Soni H, Adebiyi A. Loss of urotensin II receptor diminishes hyperglycemia and kidney injury in streptozotocin-treated mice. J Mol Endocrinol. 2022;68:167-178 pubmed publisher
Bao Y, Zhao Z, Gao H. Effect of hTIMP-1 overexpression in human umbilical cord mesenchymal stem cells on the repair of pancreatic islets in type-1 diabetic mice. Cell Biol Int. 2021;45:1038-1049 pubmed publisher
Liu Z, Ding Z, Lynch E, McCauley N, Zhou Y, Zhang K, et al. Pregestational diet transition to normal-fat diet avoids the deterioration of pancreatic β-cell function in male offspring induced by maternal high-fat diet. J Nutr Biochem. 2020;86:108495 pubmed publisher
Abdelrazek H, Kilany O, Muhammad M, Tag H, Abdelazim A. Black Seed Thymoquinone Improved Insulin Secretion, Hepatic Glycogen Storage, and Oxidative Stress in Streptozotocin-Induced Diabetic Male Wistar Rats. Oxid Med Cell Longev. 2018;2018:8104165 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Insulin Monoclonal Antibody (ICBTACLS), eBioscience

Catalog # :

14-9769-37

Quantity :

2 mg

Price :

US 1482.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 0.25 ug/mL, Western Blot: 5 ug/mL

Species :

Human, Mouse, Rat

Clone :

ICBTACLS

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.25 ug/mL, Western Blot: 5 ug/mL

Aliases :

AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin